Does Lexapro Make You Emotionless? (+5 Insights)

In this article, we discuss how Lexapro, containing escitalopram, impacts mood regulation by influencing serotonin levels in the brain, potentially leading to emotional blunting.

Does Lexapro make you emotionless?

Yes, Lexapro can make you feel emotionless or cause emotional blunting. A survey of patients taking antidepressants, including SSRIs like Lexapro, revealed that almost 50% experience emotional blunting.

However, emotional blunting may be a symptom of depression rather than a side effect of the treatment (6). These drugs effectively improve mood and reduce anxiety. However, some individuals might feel a reduced emotional response, making it difficult to express feelings of love, joy, or fear.

How does Lexapro change your emotions?

Lexapro, also known as escitalopram, is an SSRI antidepressant. It works in your brain by inhibiting serotonin reuptake and boosting the transmission of serotonin signals between nerve cells in the limbic system, influencing mood regulation and emotional processing (1).

These actions restore standard neuronal communication patterns, alleviate mood disorder symptoms, and promote emotional stability.

What are the emotional side effects of Lexapro?

Although Lexapro is generally well-tolerated, certain individuals may experience emotional side effects. The severity of these side effects may vary from person to person. Below are some of the commonly observed emotional side effects associated with Lexapro:

  • Emotional Blunting: Some individuals may feel numb or have dulled emotional response.
  • Mood changes: Lexapro may cause mood swings, resulting in shifts in emotional states, such as feeling unusually elated or down.
  • Anxiety or Agitation: In some cases, Lexapro may cause restlessness, nervousness, or anger, increasing anxiety levels.
  • Apathy or Indifference: Individuals may experience a lack of motivation and interest in activities they once enjoyed, as well as detachment or indifference towards their surroundings.
  • Emotional Instability: Some individuals may experience emotional instability, leading to sensitivity, irritability, or impulsive behaviour.

What factors can influence your emotions while on Lexapro?

When taking Lexapro, knowing that various factors can impact your emotional experiences is essential. These factors include:

  • Serotonin regulation: Lexapro primarily affects the levels of serotonin in the brain, which directly influences mood, emotions, and overall well-being. If serotonin levels are not regulated, it could lead to the risk of serotonin syndrome, which has a symptom of an altered mental state, such as agitation, confusion, and mania (7)
  • Neurochemical balance: The intricate interplay of neurotransmitters like serotonin, dopamine, and norepinephrine can significantly affect emotional states. Any disruption in their balance may influence emotional stability.
  • Personal physiology: Variations in brain chemistry and sensitivity to medications can alter how Lexapro interacts with the body, leading to diverse emotional responses.
  • Underlying mental health conditions: Pre-existing conditions like anxiety, depression, or other mental health disorders can influence how individuals respond to Lexapro treatment, affecting their emotional well-being.
  • Dosage and treatment duration: The specific Lexapro dosage and duration of treatment can impact its effects on emotional regulation, potentially leading to mood fluctuations and changes in emotional stability.
  • Lifestyle and environmental factors: External factors such as stress, lifestyle choices, and environmental triggers can contribute to emotional changes while on Lexapro, influencing the overall impact of the medication.

Monitoring and discussing emotional changes with a healthcare provider during Lexapro treatment can facilitate effective management and care.

How can emotional blunting be managed while taking Lexapro?

Managing emotional blunting while on Lexapro can involve several strategies to maintain emotional well-being:

  • Discussing emotional changes and concerns with a healthcare provider can provide valuable insights and support in managing Lexapro’s effects.
  • Studies have shown that mindfulness practices, such as cognitive-behavioural therapy (CBT), can improve emotional awareness and regulation in conjunction with Lexapro (5)
  • Maintaining a balanced diet, a regular exercise routine, and adequate sleep can contribute to overall emotional well-being and complement Lexapro’s effects (3,4)
  • Participating in talk therapy or counselling sessions can provide a supportive environment to address emotional challenges and develop effective coping strategies while taking Lexapro.
  • Learning stress reduction techniques such as deep breathing, yoga, or engaging in hobbies and activities can help mitigate the impact of emotional blunting and stress on Lexapro.
  • Building and nurturing a solid social support network of friends, family, or support groups can provide valuable emotional support and alleviate the challenges associated with emotional blunting during Lexapro treatment.
  • Scheduling regular appointments can ensure ongoing monitoring of emotional blunting and allow for necessary adjustments to the treatment plan if needed.

Patients experiencing difficulty experiencing emotions can use these strategies regularly and seek guidance to manage their feelings while on Lexapro.

When should you seek medical advice while on Lexapro?

While taking Lexapro, monitoring your physical and emotional well-being is crucial. There are specific circumstances in which you should seek medical advice:

  • If you experience mood changes, anxiety, or depression despite taking Lexapro as prescribed, consult your healthcare provider for guidance and adjustments to your treatment plan.
  • If you experience severe or unmanageable side effects such as persistent nausea, dizziness, insomnia, or sexual dysfunction, consult your healthcare provider to determine whether modifications to your medication or dosage are necessary.
  • If you experience suicidal thoughts or behaviours or notice significant mood changes, causing you to feel overwhelmed or out of control, seek immediate medical help or contact emergency services.
  • In case of an allergic reaction to Lexapro, characterized by symptoms such as hives, difficulty breathing or swelling of the face, tongue, or throat, seek medical attention immediately.
  • If you experience any sudden or significant changes in your physical health, such as irregular heartbeats, fainting, or unexplained weight changes, promptly consult your healthcare provider for an evaluation.
  • If you take other medicines, including over-the-counter drugs, supplements, or herbal products, and experience any adverse interactions or side effects while using Lexapro, promptly inform your healthcare provider for guidance.

By remaining vigilant and seeking medical advice promptly under these circumstances, you can ensure your safety and effectively manage your treatment with Lexapro.

What can you do if Lexapro doesn’t work for managing emotions?

It may take 1-4 weeks for Lexapro to start working; however, if its effect is not ideal for you, several alternative medications and therapies exist:

Pharmaceutical therapies

Medical treatment can be chosen based on consultation with a healthcare professional and your medical history while following prescribing guidelines:

  • Other SSRIs: If Lexapro proves ineffective or causes intolerable side effects, other SSRIs like Zoloft (Sertraline), Prozac (fluoxetine), or Paxil (Paroxetine) might be considered. These medications function similarly to Lexapro and can be effective alternatives for managing emotional symptoms (2).
  • Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs): Medications like Cymbalta (duloxetine) and Effexor (venlafaxine) fall under the category of SNRIs and can serve as alternatives to SSRIs. These medications affect both serotonin and norepinephrine levels in the brain and can be beneficial for managing emotional symptoms (2).
  • Atypical antidepressants. Alternative options such as Wellbutrin (bupropion) and Remeron (Mirtazapine) work through different mechanisms than SSRIs and can be considered, especially if patients do not respond well to SSRIs or experience specific side effects (2).

Non-Pharmaceutical therapies

Alternative therapies may also show results in the management of emotional symptoms. Consult with a healthcare professional to determine the best treatment.

  • Psychotherapy: Various types of psychotherapy, such as cognitive behavioural therapy (CBT), interpersonal therapy (IPT), and mindfulness-based therapy, can effectively manage symptoms like emotional bluntness (5). These therapies provide patients with coping strategies, stress management techniques, and tools for addressing underlying emotional issues.
  • Lifestyle modifications: Regular physical activity, a balanced diet, stress-reduction techniques like yoga and meditation, and ensuring adequate sleep can significantly impact emotional well-being. These lifestyle modifications can complement medication or serve as standalone strategies for managing emotional symptoms (4)
  • Alternative and complementary therapies: Some individuals may wish to explore alternative therapies such as acupuncture, herbal supplements, and dietary changes to support emotional health. Consulting with a healthcare practitioner is essential before incorporating these therapies.

Consult with a healthcare professional to determine the best alternative treatment to Lexapro based on your needs, medical history, and emotional symptoms.

Conclusion:

In this article, we have discussed the emotional effects of Lexapro, exploring how it can cause the feeling of being emotionless through its impact on serotonin levels.

We delved into the emotional side effects, factors influencing emotional experiences, and strategies for managing emotional blunting while on Lexapro.

Furthermore, we emphasized the importance of seeking medical advice if Lexapro does not provide the desired relief and offering alternatives to improve the emotional state.

Was this helpful?

Thanks for your feedback!

References

1.-

Bakshi A, Tadi P. Biochemistry, Serotonin. 2022 Oct 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 32809691. https://pubmed.ncbi.nlm.nih.gov/32809691/

2.-

Camino S, Strejilevich SA, Godoy A, Smith J, Szmulewicz A. Are all antidepressants the same? The consumer has a point. Psychol Med. 2023 Jul;53(9):4004-4011. doi: 10.1017/S0033291722000678. Epub 2022 Mar 29. PMID: 35346413. https://pubmed.ncbi.nlm.nih.gov/35346413/

3.-

Wipfli B, Landers D, Nagoshi C, Ringenbach S. An examination of serotonin and psychological variables in the relationship between exercise and mental health. Scand J Med Sci Sports. 2011 Jun;21(3):474-81. doi: 10.1111/j.1600-0838.2009.01049.x. Epub 2009 Dec 18. PMID: 20030777. https://pubmed.ncbi.nlm.nih.gov/20030777/

4.-

Hosker DK, Elkins RM, Potter MP. Promoting Mental Health and Wellness in Youth Through Physical Activity, Nutrition, and Sleep. Child Adolesc Psychiatr Clin N Am. 2019 Apr;28(2):171-193. doi: 10.1016/j.chc.2018.11.010. Epub 2019 Feb 6. PMID: 30832951. https://pubmed.ncbi.nlm.nih.gov/30832951/

5.-

Gorka SM, Young CB, Klumpp H, Kennedy AE, Francis J, Ajilore O, Langenecker SA, Shankman SA, Craske MG, Stein MB, Phan KL. Emotion-based brain mechanisms and predictors for SSRI and CBT treatment of anxiety and depression: a randomized trial. Neuropsychopharmacology. 2019 Aug;44(9):1639-1648. doi: 10.1038/s41386-019-0407-7. Epub 2019 May 6. PMID: 31060042; PMCID: PMC6785075. https://pubmed.ncbi.nlm.nih.gov/31060042/

6.-

Goodwin GM, Price J, De Bodinat C, Laredo J. Emotional blunting with antidepressant treatments: A survey among depressed patients. J Affect Disord. 2017 Oct 15;221:31-35. doi: 10.1016/j.jad.2017.05.048. Epub 2017 Jun 6. PMID: 28628765. https://pubmed.ncbi.nlm.nih.gov/28628765/

7.-

Maitland S, Baker M. Serotonin syndrome. Drug Ther Bull. 2022 Jun;60(6):88-91. doi: 10.1136/dtb.2021.000032. Epub 2022 May 12. PMID: 35551099. https://pubmed.ncbi.nlm.nih.gov/35551099/

Find a supportive therapist who can help with Depression.

Discover the convenience of BetterHelp, an online therapy platform connecting you with licensed and accredited therapists specialized in addressing issues such as depression, anxiety, relationships, and more. Complete the assessment and find your ideal therapist within just 48 hours.

 

AskYourPharm is user-supported. We may earn a commission if you sign up for BetterHelp’s services after clicking through from this site