Does Lexapro cause sinus issues? (5+ factors)

In this article, we will explore whether Lexapro causes sinus issues. Furthermore, we will also discuss what the research suggests, the contributing factors, and management strategies for dealing with sinus issues while taking Lexapro.

Does Lexapro cause sinus issues?

Yes, Lexapro can cause sinus issues. Patients taking Lexapro may experience some common sinus problems, such as a runny nose, flu-like symptoms, and sneezing (1). Lexapro, also known as Escitalopram, is a selective serotonin reuptake inhibitor (SSRI) antidepressant. 

Lexapro is used to treat and manage major depressive and generalized anxiety disorders. Lexapro may also be prescribed for social anxiety disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and menopausal symptoms(2).

Sinus issues can be serious and lead to conditions like sinusitis, commonly known as sinus infections. Sinusitis can cause a range of symptoms that can vary in severity (3).

What does research suggest?

According to research studies, Lexapro, being an SSRI, affects the levels of serotonin, a chemical neurotransmitter in the brain. Altered serotonin levels while taking Lexapro can lead to nasal symptoms such as itching, sneezing, increased mucus production, and a runny nose.

This could be because serotonin affects the nerves in the nose, although it doesn’t seem to have a direct influence on the blood vessels in the nose (4). A clinical study examined the effects of Lexapro on depressive patients with allergic rhinitis, a condition which causes nasal congestion and other symptoms.

This study suggested that Lexapro improved sleep, physical well-being, and nasal symptoms. This indicates that, for some individuals, Lexapro can help manage allergic rhinitis alongside anxiety (5).

Sinusitis may also lead to feelings of anxiety, worry, or fatigue, affecting daily life (6). According to the Food and Drug Administration (FDA), there is only a 3% risk that patients using Lexapro to treat depression may experience sinusitis or sinus infection.

Some studies suggest that antidepressants like Lexapro affect the immune system, the mechanism of action for treating depression. Lexapro reduces levels of certain inflammation-associated chemicals in the body. This mechanism is beneficial for treating depression but may increase susceptibility to infections (7).

What factors can contribute to sinus issues while taking Lexapro?

The factors that can contribute to sinus issues while taking Lexapro may include:

• Allergic to Lexapro or other SSRIs
• Exposure to bacteria or viruses that can cause infections
• Environmental factors
• A history of previous infections
• Immune system problems
• Certain medications (7)

How to manage sinus issues while taking Lexapro?

If you experience sinus issues while taking Lexapro and they worsen, please inform your healthcare provider. They may suggest the following ways to manage your symptoms:

• Over-the-counter painkillers such as Tylenol
• Antihistamine or antibiotics if prescribed by your doctor
• Getting plenty of rest
• Increasing your water intake
• Avoid smoking and common cold or flu triggers
• Reducing the use of electronic gadgets, which can put pressure on your eyes
• Rinsing your nose with saline water or using decongestant nasal sprays/drops to ease congestion (3).

How to know you have a sinus infection while taking Lexapro?

Some common signs and symptoms of a sinus infection while taking Lexapro may include:

• Headache
• Congestion or a stuffy nose
• Runny nose
• Excessive tiredness
• Fever
• Toothache
• Cough
• Facial pressure
• Sore throat
• Ear pain
• Loss of smell or taste
• Bad breath
• Thick yellow or green nasal discharge
• Postnasal drip (mucus dripping down the back of your throat)

If you experience several of these symptoms, and they persist for more than a week or are severe, you should consult a doctor. You may be diagnosed with a sinus infection, and your doctor may recommend appropriate treatment (8).

Conclusion

According to my knowledge, Lexapro can cause sinus problems, leading to symptoms such as a runny nose, flu-like symptoms, and sneezing. While Lexapro may help some patients with allergic rhinitis and anxiety, there is a small risk of sinusitis or sinus infections associated with its use.

However, it is important to note that sinus issues may also be influenced by other contributing factors. If you experience sinus issues while taking Lexapro, it is essential to consult your healthcare provider. 

References