Does Xarelto cause hair loss?
By
Dr Drielli Vital-Fujii (PhD)
Author bio
Dr Drielli Vital-Fujii, PhD, is a Pharmacist with expertise in Drug Design and Development, Enzymes, Molecular Modelling, and Photodynamic Therapy. She writes and reviews content on these topics.
Dr Drielli Vital-Fujii’s Highlights:
- Postdoctoral fellow at the Department of Biochemistry at the University of São Paulo, emphasizing therapy of neglected diseases using light.
- PhD in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Six months as an international researcher at the Center for Discovery and Innovation in Parasitic Diseases (University of California San Diego)
- Master’s degree in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Bachelor of Pharmacy at the University of Mogi das Cruzes – São Paulo / Brazil
Professional Experience:
2012 – 2018 Project manager at University of São Paulo – Pharmacy Department
Dr Drielli Vital-Fujii has worked with computational studies, synthesis, biological evaluation, design, and development of new inhibitor candidates for Chagas Disease and Leishmaniasis.
2017 – 2017 International research fellow at University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences – Center for Discovery and Innovation in Parasitic Diseases.
She used Virtual Screening (VS) and High-Throughput Screening (HTS) Integration in the Discovery of new drugs against neglected tropical diseases (NTDs).
2018 – 2019 Faculdades Oswaldo Cruz
Dr Drielli Vital-Fujii was a professor in the Faculty of Pharmacy, teaching the subjects of Pharmaceutical Chemistry and Drug Development.
2019 – 2021 Researcher in Biochemistry University of São Paulo – Biochemistry Department
She applied Photodynamic Therapy in Leishmaniasis Treatment, mentored undergraduate students in scientific activities, and wrote, executed, translated, and reported scientific projects with funding agencies.
2023-2023 UniPiaget – University Center.
Dr Drielli Vital-Fujii was a Biology, Nutrition, Physiotherapy, and Pharmacy professor.
Education:
2018 -2021 Postdoctoral at the Department of Biochemistry at the University of São Paulo
2013 -2018 PhD of Science: Drugs and Medicines at Department of Pharmacy at University of São Paulo
2012 -2013 M.Sc. of Sciences: Drugs and Medicines at the Department of Pharmacy at the University of São Paulo
2005-2008 Bachelor of Pharmacy at the University of Mogi das Cruzes
The leading publications of Dr Drielli Vital-Fujii are:
Vital-Fujii, D.G, Baptista, M.S. (2021). Progress in the photodynamic therapy treatment of Leishmaniasis. Brazilian Journal of Medical and Biological Research, 54, 1-11.
Gatti, F. M., Gomes, R.A., da Fonseca, A.L., Lima, E.J.C., Vital-Fujii, D.G., Taranto, A.G., Varotti, F.P., Trossini, G.H.G. (2020). Antiplasmodial activity of sulfonylhydrazones: in vitro and in silico approaches. Future medicinal chemistry, 13, 233-250.
Silva, E.J., Bezerra-Souza, A., Passero, L.F., Laurenti, M.D., Ferreira, G.M., Fujii, D.G.V., et al. (2018). Synthesis, leishmanicidal activity, structural descriptors and structure-activity relationship of quinoline derivatives. Future medicinal chemistry, 10, 2069-2085.
Leite, F.H.A., Froes, T.Q., da Silva, S.G., de Souza, E.I.M., Vital-Fuji,i D.G., Trossini, G.H.G., et al. (2017). An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors. European Journal of Medicinal Chemistry, 132, 322-332.
Vital, D.G., Damasceno, F.S., Rapado, L.N., Silber, A.M., Vilella, F.S., Ferreira, R.S., et al. (2017). Application of bioisosterism in design of the semicarbazone derivatives as cruzain inhibitors: a theoretical and experimental study. Journal of Biomolecular Structure and Dynamics, 35, 1244–1259.
Mello, J. F.R., Gomes, R.A., Vital-Fujii, D.G., Ferreira, G.M., Trossini, G.H.G. (2017). Fragment-based drug discovery as alternative strategy to the drug development for neglected diseases. Chemical Biology & Drug Design, 90, 1067-1078.
Pantaleao, S.Q., Fujii, D.G.V., Maltarollo, V.G., da C. Silva, D., Trossini, G.H.G., Weber, K.C., et al. (2017). The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery. Medicinal Chemistry, 13, 706-720.
Vital, D., Arribas, M., Trossini, G. (2014). Molecular Modeling and Docking Application to Evaluate Cruzain Inhibitory Activity by Chalcones and Hydrazides. Letters in Drug Design and Discovery, 11, 249-255.
Blau, L., Menegon, R.F., Trossini, G.H.G., Molino, J.V.D., Vital, D.G., Cicarelli, R.M.B., et al. (2013). Design, synthesis and biological evaluation of new aryl thiosemicarbazone as antichagasic candidates. European Journal of Medicinal Chemistry, 67, 142-151.
You can view some of Dr Drielli’s work below and links to her professional profile.
Orcid: https://orcid.org/0000-0001-9270-0466
Research Gate: https://www.researchgate.net/profile/Drielli-Gomes-Vital-Fujii
Scopus: https://www.scopus.com/authid/detail.uri?authorId=55829534000
Google Scholar: https://scholar.google.com/citations?user=F9U50AEAAAAJ&hl=pt-BR
Linkedin: linkedin.com/in/driellivital
Escavador: https://www.escavador.com/sobre/6101380/drielli-gomes-vital
CDIPD: https://cdipd.org/index.php/about-us/visiting-scientists
Does Xarelto cause hair loss?
No, Xarelto is not associated with hair loss as a side effect. In fact, it is not even listed as a side effect. Although hair thinning and loss of hair are considered common with anticoagulants, you might not need to worry about it if you’re on Xarelto (1,2).
However, side effects with medications could be unpredictable and some people may notice hair thinning. If you think Xarelto is causing hair loss, talk to your healthcare provider.
Your doctor will most likely look for other possible reasons that could be causing hair loss like mineral or vitamin deficiency, diabetes, etc. Just make sure you don’t stop taking Xarelto without your doctor’s approval.
Factors that can contribute to hair loss while taking Xarelto
While Xarelto is not directly linked to hair loss, there are several factors that can contribute to hair loss while taking the medication. These factors include underlying health conditions, such as hormonal imbalances, thyroid problems, or autoimmune disorders, which can affect hair growth (3,4).
Additionally, certain lifestyle factors like stress, poor nutrition, and inadequate hair care practices can also contribute to hair loss. It’s important to remember that individual experiences may vary, and not everyone will experience hair loss while taking Xarelto.
Some medications, including weight loss pills like Phentermine (Qsymia/Adipex), and diuretics like Hydrocholothazide, etc can also contribute to hair loss if used along with Xarelto.
What to do if you are experiencing hair loss while taking Xarelto?
If you are experiencing hair loss while taking Xarelto, there are a few steps you can take to address your concerns:
Consult your healthcare provider
It’s important to discuss your hair loss with your healthcare provider to determine the underlying cause and ensure it is not related to any other health conditions or medications you are taking.
Review your medication regimen
Your healthcare provider can review your current medications, including Xarelto, to check for any potential interactions or side effects that could be contributing to hair loss. They may suggest adjusting the dosage or exploring alternative medications if necessary.
Evaluate your lifestyle and habits
Evaluate your lifestyle factors that may be impacting hair health. This includes managing stress levels, maintaining a balanced diet with adequate nutrients, and practising good hair care routines. Making healthy lifestyle choices can support hair growth.
Consider hair care products and treatments
There are various hair care products and treatments available, such as specialized shampoos, conditioners, and topical solutions, that claim to promote hair growth. Discuss these options with your healthcare provider or a dermatologist to determine if they are suitable for your specific situation.
Remember, individual experiences may vary, and it’s crucial to work closely with your healthcare provider to determine the best course of action based on your unique circumstances.
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References
1.-
Singh R, Emmady PD. Rivaroxaban. 2023 Apr 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 32491434. https://www.ncbi.nlm.nih.gov/books/NBK557502
2.-
Rivaroxaban (Xarelto)–a new oral anticoagulant. Med Lett Drugs Ther. 2011 Aug 22;53(1371):65-7. PMID: 21860366. https://pubmed.ncbi.nlm.nih.gov/21860366/
3.-
Phillips TG, Slomiany WP, Allison R. Hair Loss: Common Causes and Treatment. Am Fam Physician. 2017 Sep 15;96(6):371-378. PMID: 28925637. https://pubmed.ncbi.nlm.nih.gov/28925637/
4.-
Rushton DH. Nutritional factors and hair loss. Clin Exp Dermatol. 2002 Jul;27(5):396-404. doi: 10.1046/j.1365-2230.2002.01076.x. PMID: 12190640. https://pubmed.ncbi.nlm.nih.gov/12190640/
