Does Wellbutrin make you hungry? 

Does Wellbutrin make you hungry? 

Wellbutrin may make some people hungry. Wellbutrin is an antidepressant, but some people mistakenly see it as a weight loss pill and expect it to curb their appetite. 

Wellbutrin enhances the amount of excitatory chemicals in your brain to counteract depression, which affects your body in a number of ways. A lot of people lose weight on Wellbutrin. However, Wellbutrin is not an appetite suppressant or a weight loss pill. 

It should actually bring your appetite back to normal, as it fights depression – which can cause loss or gain of appetite in people. Those who start to binge eat on depression may find their appetite getting back to normal when Wellbutrin starts to work. 

People who become anorexic because of depression may feel an increase in their appetite. This is just your appetite getting back to normal. 

However, Wellbutrin can also cause appetite-related side effects. Some people start to eat less, while some start to feel even more hungry. Some people may eat less because of Wellbutrin-induced bad taste in the mouth. That just depends on how your body responds to this medication. 

What does research suggest?

There is limited research on the effects of Wellbutrin on hunger. However, most studies indicate that Wellbutrin normalises eating patterns in depressed patients and enhances their energy levels. 

Some people may experience cravings during the early course of their treatment, but it usually happens because the body is not used to the enhanced effects of excitatory chemicals in your brain. It may make you feel excited, happy, sad, confused, hungry, or not hungry at all. 

However, these side effects usually begin to fade away as the body adjusts to the antidepressant and it begins to normalise the eating patterns. 

Research suggests that Wellbutrin can treat certain eating disorders in the long run and can help depressed obese people lose weight (1,2). 

What to do if Wellbutrin makes you hungry? 

It’s always best to opt for all the right foods to satiate your hunger, especially if it’s Wellbutrin-induced. A healthy and balanced diet won’t make you gain weight and you won’t have to starve yourself if your medication makes you hungry. 

On the other hand, it’s extremely important to incorporate fitness into your routine to burn all the extra calories which may start to get stored as fat in your body. It’s always best to discuss your side effects with your doctor to ensure the safety and efficacy of Wellbutrin use. 

If it’s increasing your appetite significantly or making you gain weight, your doctor may switch you to another antidepressant. Make sure you don’t make any changes to your prescription without consulting your doctor first. 

Final words

To sum up, Wellbutrin does not generally affect your appetite in a negative way and even if it does, it gets better with time. However, people are different and can respond differently to medications. The best way to deal with your side effects is to discuss them with your doctor. 

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White MA, Grilo CM. Bupropion for overweight women with binge-eating disorder: a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2013 Apr;74(4):400-6. doi: 10.4088/JCP.12m08071. PMID: 23656848; PMCID: PMC4021866. Available from:


Horne RL, Ferguson JM, Pope HG Jr, Hudson JI, Lineberry CG, Ascher J, Cato A. Treatment of bulimia with bupropion: a multicenter controlled trial. J Clin Psychiatry. 1988 Jul;49(7):262-6. PMID: 3134343. Available from:

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