Does Wellbutrin cause a bad taste in your mouth? 

Does Wellbutrin cause a bad taste in your mouth? 

Wellbutrin may or may not cause a bad taste in your mouth. It is not a common side effect of Wellbutrin, but some people have reported it. A bad or unusual taste in the mouth is often a complaint of people taking antidepressants. 

Some of these meds affect taste buds, which may cause a bad taste. However, Wellbutrin is associated with causing dry mouth or xerostomia as a side effect. This may alter the way you taste food. 

However, these early side effects will most likely go away within a few weeks of your treatment, as your body adjusts to the medication. 

What does research suggest? 

There is limited research on the effects of Wellbutrin on taste buds. However, some research studies indicate that Wellbutrin can cause a change in taste or a bad taste in the mouth as a side effect (1). 

The exact mechanism behind the taste alteration is not fully understood. It is believed that Wellbutrin may affect the taste receptors in the mouth, leading to a change in taste perception. Some individuals may describe it as having a bitter or metallic taste (2).

The incidence of this side effect varies among individuals. In clinical trials, approximately 10% to 20% of patients reported experiencing a taste disturbance while taking Wellbutrin. It’s important to note that not everyone will experience this side effect, and the severity can also vary.

If you are taking Wellbutrin and notice a persistent and bothersome change in taste, it is recommended to discuss it with your healthcare provider. Other antidepressants, like Prozac, Zoloft, etc can also alter the sense of taste. 

What to do if Wellbutrin causes a bad taste in your mouth? 

It’s always best to report to your healthcare provider if Wellbutrin causes a bad taste in your mouth. This side effect usually starts to go away on its own within a few weeks. 

However, some people may not recover from such side effects as early as other people do. One thing you can do to prevent this side effect to some extent is to take Wellbutrin with meals. This may help tone down some of the other side effects as well. 

Your doctor may also reduce your dose a little, especially if you’re a new user or if your Wellbutrin dose has recently increased. However, Wellbutrin may not suit every other individual. 

If this antidepressant is causing side effects that are affecting the quality of your life, your doctor will most likely switch you to another antidepressant. Make sure you don’t make any changes to your prescription without consulting your doctor first. 

Was this helpful?

Thanks for your feedback!



Huecker MR, Smiley A, Saadabadi A. Bupropion. 2023 Apr 9. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 29262173.


Schiffman SS. Influence of medications on taste and smell. World J Otorhinolaryngol Head Neck Surg. 2018 Mar 26;4(1):84-91. doi: 10.1016/j.wjorl.2018.02.005. PMID: 30035266; PMCID: PMC6051304.

Find a supportive therapist who can help with Depression.

Discover the convenience of BetterHelp, an online therapy platform connecting you with licensed and accredited therapists specialized in addressing issues such as depression, anxiety, relationships, and more. Complete the assessment and find your ideal therapist within just 48 hours.


AskYourPharm is user-supported. We may earn a commission if you sign up for BetterHelp’s services after clicking through from this site