Does Lexapro cause hiccups? (+5 management tips)

In this article, we will discuss whether Lexapro causes hiccups. We will also discuss the factors that can increase the risk of hiccups while taking Lexapro and the management of hiccups if they occur while using Lexapro.

Does Lexapro cause hiccups?

Lexapro does not cause hiccups. However, hiccups may occur in some Lexapro users due to various underlying factors. These factors could be related to the individual’s overall health, sensitivity to medications, or other concurrent conditions.

Lexapro (escitalopram), is a selective serotonin reuptake inhibitor antidepressant medication. It is prescribed for treating various mental disorders such as major depressive disorder and anxiety disorders (1). The common side effects of Lexapro are nausea, headache, dry mouth, appetite changes, and dizziness.

A hiccup is characterized by the sudden onset of irregular contractions in the diaphragm and intercostal muscles, swiftly followed by the closure of the larynx. This abrupt rush of air into the lungs produces the distinct “hic” sound.

Typically, hiccups resolve on their own, but when they persist for over 48 hours, they are termed as persistent hiccups, and episodes lasting longer than 2 months are referred to as intractable hiccups (2).

What does research suggest?

According to research, healthcare providers often associate hiccups with stress, anxiety, fatigue, and sleep problems. These factors can contribute to the occurrence of hiccups in some individuals and hiccups directly caused by Lexapro are rare (3).

The scientific literature and clinical trials do not strongly support hiccups as a well-established side effect of escitalopram. The majority of recognized side effects of escitalopram are related to mood and mental health (4).

There was no evidence indicating a significant incidence of hiccups associated with Lexapro. Individuals may occasionally report hiccups due to underlying anxiety and stress for the treatment of which escitalopram is prescribed (5).

What factors can contribute to hiccups while taking Lexapro?

While escitalopram itself doesn’t commonly cause hiccups, several factors could contribute to their

Underlying medical conditions

Pre-existing medical complications such as gastroesophageal reflux disorder (GERD) can trigger hiccups (7).

GERD is a condition where stomach acid and contents flow backwards into the esophagus, causing a range of symptoms, including heartburn, regurgitation, and in some cases, hiccups. Hiccups can be triggered by the irritation and stimulation of the diaphragm and nearby nerves.

Unhealthy eating habits

Consuming carbonated beverages such as soda drinks while taking escitalopram can potentially trigger hiccups. Additionally, spicy foods may irritate the diaphragm and cause hiccups (6).

Emotional factors

Emotional factors such as anxiety and stress can lead to irregular breathing patterns, including rapid and shallow breathing. These altered breathing patterns can irritate the diaphragm and potentially lead to hiccups (5).

If you experience persistent hiccups while taking escitalopram, it’s advisable to consult your healthcare provider for a proper evaluation and guidance.

How to manage Lexapro-induced hiccups?

If you experience hiccups while taking escitalopram (Lexapro), here are some tips to manage it:

Avoid triggers: Try to identify potential triggers. If there are specific foods, drinks, or habits that seem to bring on the hiccups, avoiding or minimizing exposure to these triggers can be helpful.

Lifestyle adjustments: Make lifestyle changes to reduce the chances of hiccups. This includes eating slowly, avoiding carbonated beverages, and not overeating.

Adequate hydration: Dehydration can sometimes lead to hiccups. Ensure you are properly hydrated by drinking enough water.

Manage anxiety: If anxiety or stress is contributing to your hiccups, consider stress-reduction techniques such as mindfulness, meditation, or deep breathing exercises.

Consult your healthcare provider: If the hiccups persist or become bothersome, consult your healthcare provider. They can evaluate your situation and discuss potential modifications to your treatment plan.

  • If the hiccups are thought to be linked to escitalopram, your healthcare provider may consider adjusting the dosage or exploring alternative medications.
  • In some cases, hiccups may be a symptom of an underlying medical condition. Your healthcare provider can help identify and treat any such conditions.

Remember, persistent hiccups can sometimes be a sign of an underlying medical issue, so don’t hesitate to consult a healthcare professional if they continue despite these measures.

What precautions should be taken while using Lexapro?

When taking Lexapro, it’s important to consider several precautions to ensure your safety and well-being. Here are some precautions to keep in mind:

  • Take Lexapro exactly as prescribed by your healthcare provider. Do not alter the dosage or stop taking it without their guidance.
  • Inform your healthcare provider about any pre-existing medical conditions, or other medications you are taking to avoid potential interactions or side effects.
  • Be aware of any signs of increased suicidal thoughts and report them to your healthcare provider immediately.
  • Avoid alcohol consumption while taking Lexapro, as it may exacerbate side effects and affect the medication’s effectiveness.
  • Do not exceed the prescribed dose. In case of overdose seek immediate medical attention.
  • Do not stop taking Lexapro suddenly without consulting your healthcare provider.
  • Always consult your healthcare provider if you have any concerns, or questions, or experience unusual side effects.

Remember that individual responses to medication can vary, and precautions may differ based on your specific health circumstances. It’s essential to work closely with your healthcare provider to ensure the safe and effective use of Lexapro.

Conclusion

In conclusion, while there is no direct evidence to suggest that Lexapro causes hiccups, it is important to consider the individual variability in medication reactions. Hiccups may occur in some individuals due to factors such as anxiety or other rare side effects of the medication.

It is my perspective that a holistic approach to understanding and managing hiccups is crucial, taking into account both the medication and individual circumstances, and consulting healthcare providers for personalized guidance when needed.

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References

1.-

Landy K, Rosani A, Estevez R. Escitalopram. 2023 Jan 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 32491666. https://pubmed.ncbi.nlm.nih.gov/32491666/

2.-

Cole JA, Plewa MC. Singultus. [Updated 2023 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538225/

3.-

Wieland J, Martin N, Jatoi A. Healthcare Providers’ Experiences with Hiccups in Patients with Cancer: Report of a United States National Survey. Am J Hosp Palliat Care. 2023 Aug;40(8):872-880. doi: 10.1177/10499091221130042. Epub 2022 Sep 29. PMID: 36172916. https://pubmed.ncbi.nlm.nih.gov/36172916/

4.-

Adjei K, Adunlin G, Ali AA. Impact of Sertraline, Fluoxetine, and Escitalopram on Psychological Distress among United States Adult Outpatients with a Major Depressive Disorder. Healthcare (Basel). 2023 Mar 3;11(5):740. doi: 10.3390/healthcare11050740. PMID: 36900745; PMCID: PMC10001334. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001334/

5.-

Nishikawa T, Araki Y, Hayashi T. Intractable hiccups (singultus) abolished by risperidone, but not by haloperidol. Ann Gen Psychiatry. 2015 Mar 5;14:13. doi: 10.1186/s12991-015-0051-5. PMID: 25763097; PMCID: PMC4355965. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355965/

6.-

Chang FY, Lu CL. Hiccup: mystery, nature and treatment. J Neurogastroenterol Motil. 2012 Apr;18(2):123-30. doi: 10.5056/jnm.2012.18.2.123. Epub 2012 Apr 9. PMID: 22523721; PMCID: PMC3325297. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325297/

7.-

Schreiber LR, Bowen MR, Mino FA, Craig TJ. Hiccups due to gastroesophageal reflux. South Med J. 1995 Feb;88(2):217-9. doi: 10.1097/00007611-199502000-00009. PMID: 7839166. https://pubmed.ncbi.nlm.nih.gov/7839166/

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