Does Lexapro affect the sense of smell? (+3 factors)

In this article, we will discuss whether Lexapro affects smell perception in individuals who are taking it. We will also discuss the factors that may contribute to the alteration of smell perception while taking Lexapro, and the management of changes in the sense of smell if they occur during Lexapro therapy.

Does Lexapro affect the sense of smell? 

Lexapro does not affect the sense of smell. While Lexapro can influence mood and emotions, it is generally not linked to changes in the sense of smell. Any unexpected alterations in smell perception are more likely due to other factors, such as underlying medical conditions, medication interactions, or changes in emotional well-being.

Lexapro (escitalopram) is a selective serotonin reuptake inhibitor (SSRI), antidepressant medication. It works by increasing the levels of serotonin in the brain. This is important because serotonin helps regulate our moods and emotions. Lexapro is prescribed to help with conditions like major depressive disorder and various anxiety disorders (1).

Changes in smell perception or smell-related side effects are not commonly associated with Lexapro. The primary side effects typically associated with Lexapro are related to mood, emotions, and the central nervous system (4).

What does research suggest? 

According to research, escitalopram demonstrates favorable tolerability, with associated adverse events typically being mild and temporary. While Lexapro may lead to mild side effects, there is no documented incidence of smell alteration associated with its use (2).

Research indicates that anosmia, the loss of the sense of smell, can be linked to a deficiency in serotonin (3). During the discontinuation of Lexapro, there is a possibility of serotonin deficiency, which, in rare instances, might lead to anosmia. While no reported incidents of anosmia caused by Lexapro discontinuation currently exist, it is crucial to acknowledge the potential risk. 

Research suggests that anxiety can also cause changes in smell, and anxiety-related shifts in smell function are reported by individuals (7). Therefore, it’s important to consider that changes in smell during Lexapro treatment may be attributed to anxiety rather than the drug itself.

What factors can influence smell changes while taking Lexapro?

Several potential factors can influence changes in smell perception while taking Lexapro such as:

Underlying medical conditions: Underlying medical conditions, such as sinus infections, allergies, or neurological disorders can contribute to the alteration of smell perception while taking Lexapro. These conditions can affect the sense of smell and cause it to become dulled or even lost altogether (5).

Medications:  Concurrent use of medications such as opioids or cannabinoids with Lexapro may cause smell changes (6). These changes may not be directly related to Lexapro but could be confused as a side effect. If you are taking Lexapro in combination with other medications, communicate clearly with your healthcare provider to determine the actual cause of any sensory alterations.

Psychological factors can also indirectly influence how a person perceives sensory stimuli, including smell. Changes in mood and anxiety levels, which Lexapro is often prescribed to address, can have an impact on the sense of smell (7). 

It is important to note that people can react differently to medications, and what affects one person’s sensory perception may not affect another’s. If you are experiencing changes in your sense of smell while taking Lexapro, it’s important to discuss this with your healthcare provider. They can assess your specific situation and consider potential contributing factors.

How to manage smell alterations while taking Lexapro?

 While Lexapro itself is not known to directly cause changes in the sense of smell, if smell alterations occur during Lexapro therapy, they are more likely due to underlying factors. To manage such alterations effectively, consider the following steps:

• If you’re taking Lexapro and notice changes in your sense of smell, it’s important to talk to your healthcare provider. They can check your condition and rule out other factors that might be causing the issue.

• You should also check if you’re taking any other medications with Lexapro, as interactions between drugs can affect your senses. Your healthcare provider can tell you if any of your medications may be causing the problem.

• Changes in your sense of smell can be related to underlying medical issues, such as allergies or sinus infections. Treating these conditions can help improve your sense of smell.

• Lexapro is often prescribed for mood disorders, and mood changes can indirectly affect your sense of smell. You should talk to your healthcare provider if you notice any changes in your mood or emotional well-being.

• Sometimes, sensory changes are temporary and can go away on their own. Just be patient as your body adjusts to medication or other factors.

Remember, the first step is always to consult your healthcare provider to determine the cause of smell alterations. They can provide tailored guidance and interventions based on your specific situation.

What are the potential side effects of Lexapro?

Side effects of Lexapro can vary from person to person. While many individuals tolerate the medication well and experience minimal side effects, some may encounter specific issues during their course of treatment (4).

Common side effects

Common side effects associated with the use of Lexapro may include:

• headache
• dry mouth
• nausea
• vomiting
• drowsiness
• insomnia
• dizziness
• appetite changes
• upset stomach
• sweating

Serious side effects

Serious side effects associated with Lexapro are relatively rare but can include:

• allergic reactions,
• serotonin syndrome (a potentially life-threatening condition), and
• changes in mood or behavior

It’s important to note that not everyone will experience these side effects, and many people tolerate Lexapro well. Any unusual or severe side effects should be reported to a healthcare provider promptly. They can help you weigh the benefits and risks and adjust your treatment plan as necessary.

Conclusion

In conclusion, based on available evidence, in my perspective, there is no direct association between Lexapro and alterations in the sense of smell. While the medication can influence mood and emotions by modulating serotonin levels in the brain, changes in the sense of smell are more likely to be related to other factors, such as underlying medical conditions or medication interactions. 

If any unusual sensory changes are observed during treatment, consult your healthcare provider. They can assess your specific situation, consider potential contributing factors, and provide appropriate guidance or adjustments to your treatment plan. 

References