Does Citalopram dehydrate you? (3+ strategies)

In this article, we will discuss Citalopram-induced dehydration. We will also discuss what one should do if this side effect occurs.

Does Citalopram dehydrate you?

Yes, Citalopram may cause dehydration in some individuals. Dehydration is not a commonly reported side effect associated with its use. However, people respond differently to medications and some people may experience unusual or unexpected side effects.

Citalopram (Celexa) is a commonly prescribed anti-depressant, used to treat mental health conditions like depression and anxiety (1). 

Citalopram rarely causes dehydration. Remember that the potential for side effects varies from person to person, so it is essential to have open communication with your healthcare provider when taking Citalopram or any medication.

Why does Citalopram cause dehydration? 

Citalopram causes dehydration very rarely (2). The exact mechanism by which Citalopram causes dehydration is not known but it may be due to disruption of the body’s natural mechanism by antidepressants for controlling temperature, blood pressure and fluid balance.

This interference can make the body heat up more rapidly than usual. However, some individuals indirectly experience symptoms of dehydration while taking Citalopram, such as increased thirst, dry mouth, excessive sweating, dark urine or reduced urination.

These side effects are not the same as dehydration but may potentially put you at risk of becoming dehydrated if you do not drink enough water. It is important for individuals taking Citalopram or any medication to remain hydrated by drinking plenty of fluids.

If you suspect you are experiencing dehydration or have concerns about the side effects of Citalopram, it is essential to discuss the symptoms with your healthcare provider to ensure the safe and effective use of the medication.

How to manage dehydration while taking Citalopram?

Managing dehydration while taking Citalopram (Celexa) or any medication is important for your overall health. Here are some steps you can take:

Stay hydrated: Keep yourself hydrated by drinking plenty of water even if you are not experiencing thirst.

Monitor dehydration symptoms: Maintaining proper hydration is indicated by having very pale yellow urine, while darker shades of yellow suggest increasing levels of dehydration.

Limit caffeine and alcohol: Caffeine and alcohol act as diuretics, increasing urine production and potentially leading to dehydration (3).To stay hydrated, drink water alongside these beverages and limit their consumption.

Avoid excessive sweating: Be cautious when exercising in hot weather, and take breaks to rehydrate. Wear appropriate clothing to prevent excessive sweating.

Eating habits: Eating smaller, lighter meals rich in fruits and vegetables can help regulate your body temperature and can also contribute to better hydration.

Remember that managing hydration is necessary for your overall well-being, and it is crucial to stay proactive in maintaining proper hydration levels, especially when taking medications that may affect fluid balance.

What to do if Citalopram-induced dehydration persists?

If you suspect that Citalopram is causing persistent dehydration, it is crucial to take the following steps.

  • Reach out to your healthcare provider to report your symptoms or concerns. They will assess your situation and determine whether Citalopram is indeed the cause of dehydration.
  • Your healthcare provider may review your medication regimen and consider adjusting the dosage or exploring alternative treatments.
  • Do not skip the doses or discontinue the medication on your own as it can result in withdrawal symptoms.
  • Continue to drink plenty of water to combat dehydration.

It is important to note that not everyone taking Celexa will experience this side effect. Every individual has a unique genetic makeup and responds differently to medications. Always consult your healthcare provider for personalized guidance and support.


In conclusion, while dehydration is not a commonly reported side effect of Citalopram (Celexa), some individuals may experience symptoms such as dry mouth or increased thirst while taking this medication. It is essential to maintain proper hydration and monitor unusual symptoms. If you suspect dehydration or experience severe side effects, it is advisable to consult a healthcare provider promptly. They can assess your specific situation and make necessary adjustments to your treatment plan to ensure your well-being.




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