Does Aspirin manufactured by Bayer have caffeine in it? 

Does Aspirin manufactured by Bayer have caffeine in it?

Aspirin Back & Body manufactured by Bayer Pharmaceuticals contain caffeine. According to the manufacturers, that’s the only formulation which contains Aspirin and caffeine together, and no other product contains caffeine. The amount of caffeine added to each of the pills is 32.5 mg

Potential benefits and risks of taking aspirin with caffeine 

Aspirin is a well-known OTC Non-steroidal anti-inflammatory drug (NSAID), which is used for pain, fever, and inflammation. Some Aspirin products may contain caffeine in them to boost the activity of the drug. 

Caffeine may enhance the effects of Aspirin in your body to provide better relief for your symptoms (1). Caffeine also helps with your mental lethargy when you’re sick or have a fever, and makes you feel fresh and alert. 

Both Aspirin and caffeine have also been associated with a reduced risk of certain diseases, such as Alzheimer’s disease, Parkinson’s disease, and some types of cancer.

However, this combination should not be used excessively. Aspirin is known for causing gastrointestinal side effects because of how it works (2). Caffeine may increase the intensity of these side effects, as it can affect your stomach too. 

On the other hand, Aspirin is a blood thinner and combining it with caffeine can increase the risk of bleeding, particularly in people who are already at risk for bleeding disorders.

If you take Aspirin+caffeine and consume coffee separately, it can cause even more damage to your stomach, especially if you often find your stomach disturbed. Not only Aspirin but caffeine should also be used cautiously with other NSAIDs, like Naproxen, Diclofenac, etc.

How to take Aspirin and Caffeine safely together?

You can take this OTC med safely if you are a normal healthy individual. However, people with gastrointestinal diseases or those who are at high risk of GI bleeding should seek medical advice from their provider before taking this combination.

When using OTC meds, it is also important to read the labels properly to make sure that you are taking the medication as directed. If you are confused about something, talk to your pharmacist and make sure you take the med in the best possible way and at a suitable time. 

It is also important to make sure that you don’t exceed the recommended dose. Taking too much aspirin or caffeine can be dangerous, so be sure to follow the recommended dose on the label or as directed by your doctor.

If you feel unusual after taking a combined formulation of Aspirin and caffeine, or you start to experience intense GI side effects, stop the medication immediately and seek medical attention.

Was this helpful?

Thanks for your feedback!



Thithapandha A. Effect of caffeine on the bioavailability and pharmacokinetics of aspirin. J Med Assoc Thai. 1989 Oct;72(10):562-6. PMID: 2584901. Available from:


Sostres C, Lanas A. Gastrointestinal effects of aspirin. Nat Rev Gastroenterol Hepatol. 2011 Jun 7;8(7):385-94. doi: 10.1038/nrgastro.2011.97. PMID: 21647198. Available from: