What are the directions for taking Prednisone 5mg dose pack of 48 tablets?

What are the directions for taking Prednisone 5mg dose pack of 48 tablets?

The right directions to take the Prednisone dose pack containing 48 tablets are

Days Total number of tablets/dayWhen to take the tablets
Day 1 – 46 tablets2 tablets before breakfast, 1 after lunch, 1 after dinner, and 2 at bedtime 
Day 5 – 84 tablets1 tablet before breakfast, 1 after lunch, 1 after dinner, and 1 at bedtime 
Day 9 – 122 tablets1 tablet before breakfast and 1 at bedtime 

So to break it down even further, (1,2)

  • You will have to take 24 tablets the first four days (6 tablets each day)
  • 16 tablets the next four days (4 tablets each day)
  • And 8 tablets the last four days (2 tablets each day)

This makes a total of 48 tablets in 12 days. It is best to consult your healthcare provider before starting Prednisone 48 tablets pack. 

What side effects are common with Prednisone 5mg dose pack of 48 tablets?

Common side effects of a Prednisone 5mg dose pack of 48 tablets may include (3):

  • Upset Stomach
  • Increased Appetite
  • Mood Changes
  • Difficulty Sleeping
  • Water Retention
  • Acne
  • Increased Thirst and Urination
  • Headache
  • Dizziness
  • Weakened Immune System

Remember, side effects can vary among individuals and may start to show up sooner or later, so it’s essential to follow your healthcare provider’s guidance and communicate any concerns during treatment.

How to ensure the safe and effective use of Prednisone 5mg dose pack?

To ensure the safe and effective use of a Prednisone 5mg dose pack, follow these essential guidelines (1,3):

  • Take Prednisone exactly as prescribed by your healthcare provider. Do not change the dose or stop taking it without consulting them first.
  • Finish the entire dose pack as prescribed, even if you start feeling better. Stopping it abruptly can lead to withdrawal symptoms.
  • Alcohol and high-sodium foods can worsen side effects and increase the risk of stomach problems, so avoid them during treatment.
  • Be aware of potential side effects like upset stomach, mood changes, or increased thirst. If any new or concerning symptoms arise, inform your healthcare provider promptly.
  • Inform your doctor about all medications you are taking, including over-the-counter and herbal supplements, to avoid potential interactions.
  • Take Prednisone regularly and at the same time each day. Set a reminder if needed to help you remember.
  • Prednisone can increase blood sugar levels, especially in people with diabetes. Monitor your blood sugar regularly if you have diabetes and report any significant changes to your doctor.
  • Drink plenty of water throughout the day to stay hydrated, especially if you experience increased thirst due to Prednisone.

Remember, each person’s response to Prednisone may vary, and it’s essential to communicate openly with your healthcare provider about your concerns and any new symptoms.

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Puckett Y, Gabbar A, Bokhari AA. Prednisone. 2023 Mar 27. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 30521230. https://www.ncbi.nlm.nih.gov/books/NBK534809


LABEL: PREDNISONE tablet. DailyMed [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=a784f545-f209-46d4-9350-ae64fad9e07c&type=pdf


National Library of Medicine. Prednisone: MedlinePlus Drug Information [Internet]. Bethesda (MD): U.S. National Library of Medicine. Available from: https://medlineplus.gov/druginfo/meds/a601102.html