Does Xanax cause night sweats? (3+ findings)

In this article, we will discuss whether or not Xanax causes night sweats, research findings on the relationship between Xanax and night sweats, and what to do if Xanax causes night sweats.

Does Xanax cause night sweats?

Yes, Xanax can cause night sweats. This side effect manifests differently in each individual. Night sweats are not a common side effect of Xanax.

Night sweats are a typical symptom of anxiety and panic disorders, stress can stimulate this symptom.

Xanax is believed to help treat your night sweats. However, night sweats might occur when patients use Xanax for the first time because their body needs time to adjust to the drug.

The withdrawal symptoms of Xanax cause severe night sweats if you skip doses or decide to abruptly discontinue taking it. To reduce Xanax’s withdrawal symptoms such as night sweats, it is imperative that you speak with your physician about discontinuing Xanax and gradually reducing the dosage over the course of eight weeks. (1)

What does research suggest?

There is limited research on how Xanax particularly causes night sweats, anxiolytics are known to produce this adverse effect in general. It is unclear exactly how these medications cause night perspiration to occur.

Researchers have suggested that the reason, nevertheless, might be related to how anxiolytics function. 

By binding to GABA receptors, Xanax strengthens the inhibitory effect of the GABA neurotransmitter. Xanax and other benzodiazepines bind between the alpha-1 and gamma-2 subunits of the GABA neurotransmitter. (2)

50% of presynaptic boutons (axon terminals) in your hypothalamus contain GABA, which is the main inhibitory transmitter produced by many neurons. (3)

High elevations in GABA levels can have an impact on the hypothalamus, an important brain region responsible for controlling your hunger, thirst, blood pressure, sleep, mood, and body temperature. (4)

Sweating is another function of the hypothalamus. Anxiolytics when taken in excess amounts can raise body temperature. This causes your body to begin sweating to expel the excess heat.

What should you do if Xanax causes night sweats?

If taking Xanax causes severe night sweats, consult immediately your healthcare provider. This side effect goes away over time, but in certain situations and individuals, it might not go away.

  • If you are taking Xanax at night, your healthcare provider might advise you to take it in the morning. This can help you sleep a little easier at night, but it might make you perspire throughout the day.
  • Your healthcare provider might also try lowering your Xanax dose if you’re new to the medication to help your body get used to it. The majority of Xanax-induced night sweats happen during the first week of its use. (5)
  • If the symptom of night sweats persists, your healthcare provider may switch you to another anxiolytic with fewer side effects.
  • According to a study, benztropine (a medicine that is mainly used to treat Parkinson’s disease and involuntary movement disorders) can lessen the severity of profuse sweating. The study suggests using benztropine to treat antidepressant-induced night sweats, like those caused by Effexor. It can, however, be used to treat night sweats brought on by anxiolytics. (6)

Home tips to reduce night sweats

You can enhance the quality of your sleep by following these preventive measures to stay colder before going to bed.

  • Place a cold pack underneath your pillow and turn it over so that your head is resting on a cool surface.
  • To bed, put on light-colored, loose-fitting clothes made of linen or cotton.
  • Avoid alcohol, cigarettes, spicy meals, caffeine, as well as exercising right before going to bed.
  • Apply cooling gels to your mattress coverings and pillows.
  • Use light-layered bedding, so that you may take it off during the night as needed. (7)


My study and understanding indicate that Xanax may contribute to night sweats. It varies from person to person. This is an uncommon symptom that usually goes away after one week from starting the medication. Consult your healthcare provider about reducing your dosage or switching to a different medication if you get night sweats while using Xanax.




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