Does Wellbutrin cause face flushing? (3+ factors)
By
Ivan Kahwa
Author bio
Mr Ivan Kahwa is a chemist and phytopharmaceutical scientist with expertise in chemistry, pharmacology, phytochemistry, and Nanobiotechnology. He writes and reviews content on these topics.
Mr Ivan Kahwa’s Highlights:
Guest Researcher at the University of Leipzig, Senior Research Fellow/Scientist, and Lecturer at the Department of Pharmacy, Faculty of Medicine, Mbarara University of Science and Technology.
Professional Experience:
Mr Ivan joined PHARMBIOTRAC as a research fellow/scientist during his master of science tenure. He contributed to the development of most of the phytopharmaceutical products in the project. Furthermore, he participated in carrying out the pharmacological activities of the developed products in laboratory animals such as mice and rats in order to develop proper doses hence leading to pre-clinical studies.
With the above relevant research experience, Ivan started to work with the University of Leipzig on collaborative projects with Mbarara University to develop the chemistry of Ugandan Medicinal plants and their pharmacological activities. This was coupled with several consultative positions by different German NGOs. Mr. Kahwa is also a supporting in the teaching and learning at the Departments of Pharmacy and Pharmaceutical Sciences, Faculty of Medicine, Mbarara University of Science and Technology.
With the increase in antimicrobial resistance globally, Ivan retooled his thinking towards developing new naturally derived antibiotic regimens from Ugandan propolis with the assistance of nanotechnology to improve their delivery to microbial cells. Kahwa has also published over 28 articles in peer-reviewed journals and he is currently reviewing for many journals.
Education:
2023-2027: PhD in Pharmaceutical Sciences (ongoing) with a focus on Pharmaceutical Microbiology and Nanobiology at Mbarara University of Science and Technology.
2022: 2Msc. in Pharmacognosy and Natural Medicine Science at Mbarara University of Science and Technology.
2018: Bachelor of Science (Chemistry) at Mbarara University of Science and Technology.
Publications:
▪ Iqbal, S., Jabeen, F., Kahwa, I., & Omara, T. 2023. Suberosin Alleviates Thiazolidinedione-Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4-LPCAT3 and PI3K-AKT Signaling Pathways. Cardiovascular Toxicology. https://doi.org/10.1007/s12012-023-09804-7
▪ Gupta, A. K., Yadav, R., Sharma, S., Sawale, J., & Kahwa, I. 2023. Anti-ageing Activity and Antioxidant Activity of Methanol Extracts of Leaves and Flowers of Salvia officinalis and Rosmarinus officinalis. Journal of Young Pharmacists, 15(3), 448–455. https://doi.org/10.5530/jyp.2023.15.60
▪ Tolo, C.U., Kahwa, I., Nuwagira, U., Weisheit, A. and Ikiriza, H., 2023. Medicinal plants used in treatment of various diseases in the Rwenzori Region, Western Uganda. Ethnobotany Research and Applications, 25, pp.1-16.
https://ethnobotanyjournal.org/index.php/era/article/view/4683
▪ Kahwa, I., Ajayi, C.O., Yadav, R., Chauhan, N.S., Shah, K., Abdelgadir, A.A., Shegena, E.A., Daniel, S., Omara, T., Asiimwe, J.B. and Ikiriza, H., 2023. Pharmacognostic and phytochemical studies as an invaluable approach for correct identification of medicinal plants: The case of Artemisia vulgaris L. substituted for Artemisia annua L. in Western Uganda. TMR Integr Med, 7, p.e23004.
https://doi.org/10.53388/TMRIM202307004
▪ Nalimu, F., Oloro, J., Kahwa, I. and Ogwang, P.E., 2021. Review on the phytochemistry and toxicological profiles of Aloe vera and Aloe ferox. Future Journal of Pharmaceutical Sciences, 7, pp.1-21.
https://doi.org/10.1186/s43094-021-00296-2
▪ Elamin, O.H.S., Ali, M.A., Elgezuli, I.A.A., Bashir, M.A. and Kahwa, I., 2021. Diagnosis of pre-and post-treatment of echinococcus granulosus with counter current immune electrophoresis and bacterial co-agglutination. Journal of Microbiology and Infectious Diseases, 11(02), pp.88-94.
https://doi.org/10.5799/jmid.951600
Published book Chapter
▪ Kahwa, I., Ayesiga, I., Nakalema, S., Alinaiswe, R., Mbabazi, R. and Iqbal, S., 2023. Natural products in the management of onchocerciasis. In Natural Products in Vector-Borne Disease Management (pp. 63-80). Academic Press. Book Chapter.
https://doi.org/10.1016/B978-0-323-91942-5.00012-4
Submitted manuscripts Under Review:
▪ Comparison of the Wound Healing Activity of the Leaf and Leaf Ash Extracts of Vernonia amygdalina in Rats. Journal name: Clinical Phytoscience
▪ Ethnobotanical Survey of Medicinal plants used in the management of cancer in Uganda. Journal name: Journal of Herbal Medicine
▪ Ethnobotanical survey and phytochemical screening of medicinal plants used in treatment of epilepsy by PROMETRA-Uganda Traditional Health Practitioners in Mpigi District, Uganda. Journal name: Journal of Ethnopharmacology
Submitted book chapters under review
1.Book title: Algae as a Natural Solution for Water-Food-Energy Nexus, Section 4: Microalgae and cyanobacteria for food applications, Chapter 4.6: Safety, toxicological and allergenic aspects of using algae for food. Authors: Christine Kyarimpa, Tom Omute, Caroline K. Nakiguli, Alice V. Khanakwa4, Christopher Angiro, Ivan Kahwa, Fortunate Ahumuza, Timothy Omara*. Publisher: Springer Nature Singapore Pte Ltd. 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore.
2.Book title: Nutraceuticals Inspiring the Contemporary Therapy for Lifestyle Diseases. Chapter: Nutraceutical applications of Seaweeds and their Phytocompounds in Nutrition and Treatment of Diseases. Authors: Ivan Kahwa, Timothy Omara , Innocent Ayesiga , Gael Noel Neh Neba Ambe , Zehbanaz Javidbhai Panwala , Rachel Mbabazi , Shabnoor Iqbal , Christine Kyarimpa , Christine Betty Nagawa , Kamal Shah ,Nagendra Singh Chauhan* Publisher: CRC Press
You can view my works on the following professional sites:
Research Gate: https://www.researchgate.net/profile/Ivan-Kahwa
Google Scholar: https://scholar.google.com/citations?user=tOwrvqoAAAAJ&hl=en
ORCID: https://orcid.org/0000-0002-6440-3437
Linkedin: https://de.linkedin.com/in/ivan-kahwa-865450159
In this article, we will discuss face flushing caused by Wellbutrin (Bupropion). We will also discuss factors influencing face flushing and what one should do to manage this side effect.
Does Wellbutrin cause face flushing?
Wellbutrin (Bupropion) may cause face flushing in some individuals. However, it is not a common side effect and the incidence is low. It is important to note that people are different and they can react differently to medications.
Face flushing is usually caused by increased blood flow, anxiety, or certain medications. It results in redness and warmth on the face and neck.
If you begin to notice the face flushing right after taking your first Wellbutrin dose, you should immediately seek medical attention as this could be a sign of an allergic reaction to this antidepressant.
If this side effect develops with time and is mild, it will likely clear up as your body adjusts to the medication. Wellbutrin is an antidepressant medication used to treat depression and aid in smoking cessation. It works on neurotransmitters in the brain to help improve mood and reduce cravings (1).
Make sure you discuss your concerns with your healthcare provider and learn more about the antidepressant you are currently taking.
What is the incidence of face flushing on Wellbutrin?
The incidence of face flushing as a side effect of Wellbutrin can vary, but it is generally considered a relatively uncommon side effect occuring in less than 10% of users (2). However, the exact frequency can vary among individuals.
Wellbutrin use can sometimes cause anaphylaxis-severe allergic reaction which can be fatal if not treated. The symptoms of anaphylaxis due to Wellbutrin include facial swelling and redness, rash and breathing problems (3).
It is important to consult with a healthcare provider for personalized information and guidance.
What factors can contribute to face flushing while taking Wellbutrin?
Several factors can contribute to facial flushing while taking Wellbutrin, including:
Individual sensitivity: People react differently to medications and some people may be more prone to side effects like facial flushing.
Dosage: Higher doses of Wellbutrin may increase the likelihood of side effects, including face flushing.
Alcohol and caffeine: Alcohol and caffeine consumption can exacerbate flushing. Limit your alcohol and caffeine consumption while taking Wellbutrin.
Drug interactions: Interactions with other drugs and supplements could increase the risk of certain side effects such as face flushing.
Allergic reactions: In rare cases, an allergic reaction to Wellbutrin can cause face flushing.
Stress: Increased stress levels can trigger hormonal changes that contribute to acne flare-ups and facial flushing.
Underlying conditions: Pre-existing medical conditions or skin sensitivities may make flushing more likely.
Always consult with a healthcare professional if you experience facial flushing or have concerns about side effects while taking Wellbutrin. They can provide guidance on managing these symptoms.
What to do if Wellbutrin causes facial flushing?
It is best to report Wellbutrin-induced face flushing to your healthcare provider. They may try dose reduction to reduce the incidence of this side effect.
This may or may not work, as some people may experience side effects that are not dose-dependent and it’s just how Wellbutrin generally makes them feel. Face flushing usually ranges from mild to moderate and is easily distinguished because severe allergy causes breathing difficulties and swelling of the face and throat.
If face flushing is bothersome, your doctor may discontinue Wellbutrin, after which this side effect will eventually start to clear up on its own. Do not discontinue the medication on your own as it may lead to discontinuation syndrome, characterized by symptoms such as hallucinations, agitation, increased heart rate, tremors etc (4).
Conclusion
In conclusion, face flushing can be caused by Wellbutrin (Bupropion) use, though it is relatively uncommon. While many individuals tolerate Wellbutrin well without experiencing this side effect, it is essential to be aware of its possibility.
If you notice your face flushing while taking Wellbutrin, it is crucial to consult with a healthcare professional. They can assess your specific situation, make any necessary adjustments to your treatment, and provide guidance on managing this side effect.
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References
2.-
Wasif N, Wasif K, Saif MW. Bupropion-Induced Acute Dystonia with Dose Escalation and Use of Naranjo Nomogram. Cureus. 2017 Apr 12;9(4):e1157. doi: 10.7759/cureus.1157. PMID: 28507829; PMCID: PMC5429148.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429148/
3.-
Bupropion (Oral Route)https://www.mayoclinic.org/drugs-supplements/bupropion-oral-route/precautions/drg-20062478#:~:text=This%20medicine%20may%20cause%20a,trouble%20breathing%2C%20or%20chest%20pain.
4.-
Gabriel M, Sharma V. Antidepressant discontinuation syndrome. CMAJ. 2017 May 29;189(21):E747. doi: 10.1503/cmaj.160991. PMID: 28554948; PMCID: PMC5449237.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449237/#:~:text=The%20mnemonic%20FINISH%20summarizes%20the,disturbances%20(%E2%80%9Cburning%2C%E2%80%9D%20%E2%80%9C
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