Does Melatonin show up on a drug test?

Does Melatonin show up on a drug test?

No, Melatonin does not show up on a drug test. Melatonin is not a medication. It is a supplement and is already present in your body. 

However, some health conditions and improper lifestyles can cause this hormone to not work as well as it should. In this case, Melatonin supplements are recommended to help regulate your circadian rhythm and normalize your normal sleep patterns. 

If you have been taking Melatonin and you have to go for a drug test, it will most likely not show up. 

How is Melatonin different from drugs that show up on a drug test?

As stated earlier, Melatonin is a hormone naturally produced by the body to regulate sleep-wake cycles. It is available as an over-the-counter supplement to help promote sleep (1,2). 

Unlike drugs that are commonly tested for in drug screenings, such as illegal substances or certain medications, Melatonin is not typically included in standard drug tests (3).

Drug tests are designed to detect specific drugs or their metabolites in the body, primarily focusing on substances that are commonly abused or have the potential for misuse (3,4). 

Melatonin, being a naturally occurring hormone and commonly used for sleep support, is not considered a drug of abuse and is not typically screened for in standard drug tests (5). 

However, it’s important to note that drug tests can vary depending on their purpose and the substances being tested. There may be specialized tests designed to detect specific medications, including Melatonin if they are of particular concern in certain settings.

Examples of drugs that show up on a drug test

Some examples of drugs that standard drug tests focus on include: (3,4)

  • Marijuana (THC): Drug tests can detect the presence of tetrahydrocannabinol (THC), the psychoactive compound found in marijuana. This is often tested for in both recreational and workplace drug screenings.
  • Opioids: Drug tests can detect various opioids, such as codeine, morphine, heroin, oxycodone, and fentanyl. These substances are commonly prescribed as pain relievers or can be obtained illegally.
  • Amphetamines: Drugs like amphetamine and methamphetamine, commonly known as “speed” or “meth,” can be detected in drug tests. These stimulants affect the central nervous system and are often associated with recreational use or misuse.
  • Cocaine: Drug tests can detect the presence of cocaine, a powerful stimulant drug derived from the coca plant. It is commonly associated with illegal drug use.
  • Benzodiazepines: Benzodiazepines, such as diazepam (Valium) and alprazolam (Xanax), are prescription medications used to treat anxiety, insomnia, and other conditions. They can be detected in drug tests and are sometimes misused.
  • Barbiturates: Barbiturates, such as phenobarbital and secobarbital, are sedative-hypnotic drugs that can be detected in drug tests. They have various medical uses but are also associated with misuse.
  • Phencyclidine (PCP): PCP is a hallucinogenic drug that can be detected in drug tests. It is commonly known as “angel dust” and is associated with recreational use.

How to ensure the proper use of Melatonin OTC supplements?

To ensure the proper use of Melatonin OTC supplements, here are some important considerations (1,2):

Follow Recommended Dosage

Read and follow the instructions on the Melatonin supplement packaging carefully. Stick to the recommended dosage provided by the manufacturer or as advised by your healthcare provider. Taking more than the recommended dose does not necessarily improve sleep quality and may increase the risk of side effects.

Use for Short-Term Use

Melatonin is generally recommended for short-term use to help with occasional sleeplessness or jet lag. It is not intended for long-term or continuous use without the guidance of a healthcare provider.

Timing of Use

Take Melatonin approximately 30 minutes to one hour before your intended bedtime. This allows the supplement to be absorbed and take effect when you want to fall asleep. Make sure you eat dinner earlier, as Melatonin absorbs at a higher rate when taken on an empty stomach

Create a Sleep-Friendly Environment

While using Melatonin, create a sleep-friendly environment to optimize its effectiveness. This includes ensuring a dark, quiet, and comfortable sleep environment, avoiding stimulating activities or electronic devices close to bedtime, and practising relaxation techniques.

Be Aware of Potential Side Effects

Although generally considered safe for most people, Melatonin can have potential side effects such as daytime drowsiness, headaches, or stomach discomfort. If you experience any unusual or bothersome symptoms, discontinue use and consult with your healthcare provider.

Remember, Melatonin supplements are intended to aid with sleep, but they may not be suitable for everyone or address underlying sleep issues. If you have chronic sleep problems or concerns about your sleep patterns, it’s important to consult with a healthcare provider.

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References

1.-

Savage RA, Zafar N, Yohannan S, Miller JMM. Melatonin. 2022 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 30521244. https://www.ncbi.nlm.nih.gov/books/NBK534823

2.-

Fatemeh G, Sajjad M, Niloufar R, Neda S, Leila S, Khadijeh M. Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials. J Neurol. 2022 Jan;269(1):205-216. doi: 10.1007/s00415-020-10381-w. Epub 2021 Jan 8. PMID: 33417003. https://pubmed.ncbi.nlm.nih.gov/33417003/

3.-

McNeil SE, Chen RJ, Cogburn M. Drug Testing. 2023 Jan 16. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 29083751. https://www.ncbi.nlm.nih.gov/books/NBK459334/

4.-

Aro HJ, Hussain A, Bobrin BD. Controlled Substances. 2023 Apr 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 32119270. https://www.ncbi.nlm.nih.gov/books/NBK554383

5.-

Tordjman S, Chokron S, Delorme R, Charrier A, Bellissant E, Jaafari N, Fougerou C. Melatonin: Pharmacology, Functions and Therapeutic Benefits. Curr Neuropharmacol. 2017 Apr;15(3):434-443. doi: 10.2174/1570159X14666161228122115. PMID: 28503116; PMCID: PMC5405617. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405617/