Does Fluvoxamine cause joint pain? (3+ tips)

In this article, we will discuss joint pain associated with Fluvoxamine use – a selective serotonin reuptake inhibitor. We will also discuss some research studies and what one should do if this side effects.

Does Fluvoxamine cause joint pain?

Fluvoxamine may cause joint pain in some individuals. It is a listed side effect but is uncommon or rare. The incidence of this side effect is not well-established as inconsistent cases of joint pain with Fluvoxamine have been reported.

Fluvoxamine is an antidepressant used to treat depression and anxiety (1). If you are new to this antidepressant and you feel pain in your joints, this could be an early side effect of Fluvoxamine and will most likely fade away within a few weeks as your body adjusts to the medication.

It is important to note that people can respond differently to Fluvoxamine and they have different factors affecting their health – that may contribute to Fluvoxamine-induced side effects. If you are taking Fluvoxamine and your joints hurt, consult your healthcare provider.

What does research suggest? 

There is limited data available on the occurrence of joint pain due to Fluvoxamine use. However, research studies have shown that the use of SSRIs, like Fluvoxamine, can lead to an increased risk of bone fractures and a decrease in Bone Mineral Density (BMD) (2).

Another study indicated that older adults both men and women, who take certain selective serotonin reuptake inhibitors (SSRIs) like Fluvoxamine are at risk of experiencing greater bone loss (3).

In elderly men, SSRIs were linked to lower bone density, while in elderly women, they were associated with higher annual bone loss (3).

As the above studies indicate, joint pain as a side effect is not only associated with Fluvoxamine alone but some other antidepressants also show this side effect such as Sertraline, Citalopram, Trazodone etc.

What to do if Fluvoxamine causes joint pain?

If you are experiencing joint pain while taking Fluvoxamine, it is important to discuss this with your healthcare provider. If your healthcare provider believes that Fluvoxamine is the main culprit, they may initially reduce the dose to see if it works.  

If dose reduction does not work, they may gradually discontinue the medication or switch to another antidepressant with fewer side effects.

However, it is important to note that do not discontinue the antidepressant on your own without consulting your doctor as it can cause horrible withdrawal symptoms such as hallucinations, agitation, dizziness, nausea, vomiting etc (4).

Tips to manage joint pain while taking Fluvoxamine

If you are experiencing joint pain while taking Fluvoxamine, consider the following tips to help manage the discomfort:

  • Applying heat or cold packs to the affected joints may provide relief. Experiment with both to see which works best for you.
  • Ensure you get enough rest, and try to avoid putting excessive strain on the affected joints. Use proper body mechanics and joint protection techniques.
  • Over-the-counter pain relievers, such as acetaminophen or non-steroidal anti-inflammatory drugs, may help alleviate joint pain. However, consult your doctor before using this medication to ensure they won’t negatively interact with Fluvoxamine.
  • Some people find relief through alternative therapies such as acupuncture or massage. Consult with your healthcare provider before trying these methods.
  • Stay well hydrated, as dehydration can sometimes contribute to joint discomfort. Maintain a balanced diet with sufficient nutrients, including those important for joint health, such as omega-3 fatty acids and vitamin D.
  • Engage in low-impact exercises, such as swimming or walking, to help keep your joints flexible. Consult your doctor before starting any new exercise regimen.
  • Following a weight management program and adjusting your diet can help reduce joint pain.
  • Monitor your joint discomfort, if it is increasing then make sure to contact your physician to discontinue or alter the medication.


Based on my experience and the information available, I can say Fluvoxamine can cause joint pain in some individuals. It is important to note that individual responses to medications vary.

If you are experiencing joint pain while taking Fluvoxamine. I suggest to consult this with your healthcare provider. They can assess your specific situation, provide guidance on managing the discomfort, and consider potential adjustments to your treatment plan if needed.



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