Does Citalopram Cause Shakiness? (3+ Case Reports)

By Ivan Kahwa

Page last updated: 02/01/2024 | Next review date: 02/01/2026

Author bio

Mr Ivan Kahwa is a chemist and phytopharmaceutical scientist with expertise in chemistry, pharmacology, phytochemistry, and Nanobiotechnology. He writes and reviews content on these topics.

Mr Ivan Kahwa’s Highlights:

Guest Researcher at the University of Leipzig, Senior Research Fellow/Scientist, and Lecturer at the Department of Pharmacy, Faculty of Medicine, Mbarara University of Science and Technology.

Professional Experience:

Mr Ivan joined PHARMBIOTRAC as a research fellow/scientist during his master of science tenure. He contributed to the development of most of the phytopharmaceutical products in the project. Furthermore, he participated in carrying out the pharmacological activities of the developed products in laboratory animals such as mice and rats in order to develop proper doses hence leading to pre-clinical studies.

With the above relevant research experience, Ivan started to work with the University of Leipzig on collaborative projects with Mbarara University to develop the chemistry of Ugandan Medicinal plants and their pharmacological activities. This was coupled with several consultative positions by different German NGOs. Mr. Kahwa is also a supporting in the teaching and learning at the Departments of Pharmacy and Pharmaceutical Sciences, Faculty of Medicine, Mbarara University of Science and Technology.

With the increase in antimicrobial resistance globally, Ivan retooled his thinking towards developing new naturally derived antibiotic regimens from Ugandan propolis with the assistance of nanotechnology to improve their delivery to microbial cells. Kahwa has also published over 28 articles in peer-reviewed journals and he is currently reviewing for many journals.

Education:

2023-2027: PhD in Pharmaceutical Sciences (ongoing) with a focus on Pharmaceutical Microbiology and Nanobiology at Mbarara University of Science and Technology.

2022: 2Msc. in Pharmacognosy and Natural Medicine Science at Mbarara University of Science and Technology.

2018: Bachelor of Science (Chemistry) at Mbarara University of Science and Technology.

Publications:

▪ Iqbal, S., Jabeen, F., Kahwa, I., & Omara, T. 2023. Suberosin Alleviates Thiazolidinedione-Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4-LPCAT3 and PI3K-AKT Signaling Pathways. Cardiovascular Toxicology. https://doi.org/10.1007/s12012-023-09804-7

▪ Gupta, A. K., Yadav, R., Sharma, S., Sawale, J., & Kahwa, I. 2023. Anti-ageing Activity and Antioxidant Activity of Methanol Extracts of Leaves and Flowers of Salvia officinalis and Rosmarinus officinalis. Journal of Young Pharmacists, 15(3), 448–455. https://doi.org/10.5530/jyp.2023.15.60

▪ Tolo, C.U., Kahwa, I., Nuwagira, U., Weisheit, A. and Ikiriza, H., 2023. Medicinal plants used in treatment of various diseases in the Rwenzori Region, Western Uganda. Ethnobotany Research and Applications, 25, pp.1-16.

https://ethnobotanyjournal.org/index.php/era/article/view/4683

▪ Kahwa, I., Ajayi, C.O., Yadav, R., Chauhan, N.S., Shah, K., Abdelgadir, A.A., Shegena, E.A., Daniel, S., Omara, T., Asiimwe, J.B. and Ikiriza, H., 2023. Pharmacognostic and phytochemical studies as an invaluable approach for correct identification of medicinal plants: The case of Artemisia vulgaris L. substituted for Artemisia annua L. in Western Uganda. TMR Integr Med, 7, p.e23004.

https://doi.org/10.53388/TMRIM202307004

▪ Nalimu, F., Oloro, J., Kahwa, I. and Ogwang, P.E., 2021. Review on the phytochemistry and toxicological profiles of Aloe vera and Aloe ferox. Future Journal of Pharmaceutical Sciences, 7, pp.1-21.

https://doi.org/10.1186/s43094-021-00296-2

▪ Elamin, O.H.S., Ali, M.A., Elgezuli, I.A.A., Bashir, M.A. and Kahwa, I., 2021. Diagnosis of pre-and post-treatment of echinococcus granulosus with counter current immune electrophoresis and bacterial co-agglutination. Journal of Microbiology and Infectious Diseases, 11(02), pp.88-94.

https://doi.org/10.5799/jmid.951600

Published book Chapter

▪ Kahwa, I., Ayesiga, I., Nakalema, S., Alinaiswe, R., Mbabazi, R. and Iqbal, S., 2023. Natural products in the management of onchocerciasis. In Natural Products in Vector-Borne Disease Management (pp. 63-80). Academic Press. Book Chapter.

https://doi.org/10.1016/B978-0-323-91942-5.00012-4

Submitted manuscripts Under Review:

▪ Comparison of the Wound Healing Activity of the Leaf and Leaf Ash Extracts of Vernonia amygdalina in Rats. Journal name: Clinical Phytoscience

▪ Ethnobotanical Survey of Medicinal plants used in the management of cancer in Uganda. Journal name: Journal of Herbal Medicine

▪ Ethnobotanical survey and phytochemical screening of medicinal plants used in treatment of epilepsy by PROMETRA-Uganda Traditional Health Practitioners in Mpigi District, Uganda. Journal name: Journal of Ethnopharmacology

Submitted book chapters under review

1.Book title: Algae as a Natural Solution for Water-Food-Energy Nexus, Section 4: Microalgae and cyanobacteria for food applications, Chapter 4.6: Safety, toxicological and allergenic aspects of using algae for food. Authors: Christine Kyarimpa, Tom Omute, Caroline K. Nakiguli, Alice V. Khanakwa4, Christopher Angiro, Ivan Kahwa, Fortunate Ahumuza, Timothy Omara*. Publisher: Springer Nature Singapore Pte Ltd. 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore.

2.Book title: Nutraceuticals Inspiring the Contemporary Therapy for Lifestyle Diseases. Chapter: Nutraceutical applications of Seaweeds and their Phytocompounds in Nutrition and Treatment of Diseases. Authors: Ivan Kahwa, Timothy Omara , Innocent Ayesiga , Gael Noel Neh Neba Ambe , Zehbanaz Javidbhai Panwala , Rachel Mbabazi , Shabnoor Iqbal , Christine Kyarimpa , Christine Betty Nagawa , Kamal Shah ,Nagendra Singh Chauhan* Publisher: CRC Press

You can view my works on the following professional sites:

Research Gate: https://www.researchgate.net/profile/Ivan-Kahwa

Google Scholar: https://scholar.google.com/citations?user=tOwrvqoAAAAJ&hl=en

ORCID: https://orcid.org/0000-0002-6440-3437

Linkedin: https://de.linkedin.com/in/ivan-kahwa-865450159

Ivan Kahwa

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This article delves into the question: Does citalopram cause shakiness? We will explore scientific evidence to provide insights into this query and offer actionable steps to take if you experience shakiness when taking citalopram.

Does Citalopram cause shakiness?

Yes, citalopram can lead to shakiness. Shakiness is a common side effect of many antidepressants, especially selective serotonin reuptake inhibitors (SSRIs) like citalopram. (1)

The intensity of these tremors can vary from person to person and often depends on the dosage. These tremors occur because citalopram increases serotonin levels in the brain. Serotonin is an excitatory neurotransmitter that helps improve mood.

It’s worth noting that while tremors are a known side effect, not everyone experiences them.

What does research suggest?

Tremors and shaking are known side effects of citalopram. Several studies and case reports have suggested a potential connection between citalopram use and the emergence of tremors.

In one case, a patient developed titubation and essential tremor during citalopram treatment. The authors suggest that citalopram might have triggered these tremors and advocate for vigilant monitoring by healthcare providers when prescribing this medication. (2)

Another report involved a patient who experienced dystonic rabbit syndrome, characterised by head and neck tremors after taking citalopram. This suggests a potential connection between citalopram and the onset of these tremors. (3)

A case series highlighted 9 patients who developed tremors on citalopram. Healthcare providers were advised to monitor for such side effects when prescribing Citalopram. (4)

Another case described a patient who developed parkinsonism, similar to Parkinson’s disease, while on citalopram. This suggests a potential association between citalopram use and parkinsonism, highlighting the significance of monitoring for movement disorders when prescribing the medication. (5)

Who is more susceptible to Citalopram-induced shakiness?

Some people are at higher risk of experiencing citalopram-induced tremors or shakiness.

Here are some factors that can potentiate the risk of developing tremors while taking Citalopram. (6)

Polypharmacy: Those taking multiple medications in addition to citalopram may have an increased risk of developing tremors. Interactions between medications can sometimes lead to side effects, including tremors.
Older Age: Older adults may be more susceptible to citalopram-induced tremors, as they can be more sensitive to medication side effects. Monitoring is particularly important in this age group.
High Dose: Taking citalopram at higher doses may elevate the risk of developing tremors. Dose-dependent side effects are common and more pronounced
Chronic Use: Individuals on citalopram for an extended period are more likely to experience side effects, including tremors. Prolonged exposure to the medication increases the risk.
Overdose: Taking citalopram in excessive amounts can lead to severe side effects, including tremors. It is crucial to use this medication as prescribed to minimise the risk of overdose.
Underlying Movement Disorders: People who already have movement disorders, such as Parkinson’s disease or other similar conditions, may be more susceptible to tremors triggered by citalopram. The medication can potentially exacerbate existing movement problems.

What to do if citalopram causes shakiness?

If you experience shakiness as a side effect of citalopram, it’s essential to take the following steps for effective management:

Contact your doctor

The first and most crucial step is to get in touch with your healthcare provider. They can assess your condition, adjust your dosage, or review your prescription to address the shakiness. They may shift you to some other antidepressants that do not cause tremors.

Avoid alcohol and caffeine

Alcohol can interact with citalopram and worsen side effects, including shakiness. It’s wise to minimise or eliminate alcohol consumption while taking this medication. Reducing your intake of caffeinated beverages can help manage the side effects, including shakiness, associated with citalopram.

Don’t stop Citalopram abruptly

It’s vital not to abruptly discontinue citalopram, as this may worsen withdrawal symptoms, including shakiness. If you wish to discontinue the medication, consult your healthcare provider for a safe and gradual tapering plan.

Maintain a healthy lifestyle

A balanced diet, regular exercise, and staying well-hydrated can contribute to your overall well-being and potentially help manage side effects. A healthy lifestyle can complement your treatment plan.

Conclusion

In conclusion, shakiness is a side effect of citalopram, particularly as it is classified as a selective serotonin reuptake inhibitor (SSRI). This side effect is relatively common and should be considered when using the medication. Consulting your healthcare provider for guidance and monitoring is vital when dealing with this potential side effect.