Does Citalopram affect driving? (3+ management)

In this article, we will explore the influence of Citalopram on driving and offer insights on how individuals who are on this medication can ensure their safety on the road.

Does Citalopram affect driving?

Yes, Citalopram (Celexa) can affect driving. Frequently, the impact of Citalopram on driving arises from side effects linked to this medication, such as drowsiness and dizziness. Therefore, it is advisable to refrain from driving until you are sure of how this medication affects you (1,2).

Although the impact of Citalopram on driving is considered a precaution associated with this medication, it can vary from person to person. For most individuals, Citalopram does not significantly impair their driving abilities.

If you are new to this medication, it is important to be aware of the potential side effects of Citalopram and how they can affect an individual’s quality of life. 

How does Citalopram affect driving?

Citalopram can potentially impact an individual’s ability to drive due to side effects that can result in altered mental alertness and psychomotor impairment (1). These factors collectively influence a person’s capacity to drive safely.

Citalopram is a selective serotonin receptor inhibitor (SSRI) antidepressant that works by altering serotonin levels in the brain. It exerts its effects on the central nervous system (CNS) and brain chemistry, resulting in side effects such as fatigue, drowsiness, dizziness, and sedation, all of which contribute to impaired driving (1,2,3).

Initially, it is advisable to wait for Citalopram to take effect and observe how your body responds to the medication. If it induces the aforementioned side effects, it is best to refrain from driving.

It is important to note that many individuals adapt to these side effects over time, making it easier for them to drive safely. Additionally, individuals who have been on this medication before normally have an understanding of how it affects them and if it does not impede their driving abilities, they can continue to drive.

Other side effects of Citalopram that can affect driving

Additional side effects of Citalopram that can impact an individual’s driving abilities include:

  • Restless leg syndrome – While uncommon, Citalopram may also cause restless leg syndrome in some individuals, leading to involuntary movements of the lower extremities that can affect one’s driving ability (4).
  • Citalopram may also induce headaches, euphoria and dissociation, which may impair an individual’s capacity to concentrate on their surroundings, posing a danger while driving (1,2,3,5).

Management of driving impairment caused by Citalopram

While taking this medication it is crucial to maintain open and frequent consultations with your prescribing healthcare provider. If you experience difficulty driving while taking this medication, you should immediately report this to your healthcare provider.

Your healthcare provider will assess your side-effect profile and offer guidance on how to address your impaired ability to drive. They may also adjust your medication’s dosage to reduce the intensity of drowsiness or dizziness and assist your body in adjusting to this medication.

Furthermore, your doctor may recommend transitioning to alternative antidepressants,such as Bupropion or Venlafaxine, which can enhance your mood and energy, potentially reducing fatigue and drowsiness and lowering the risk of impaired driving.

Recommendations for driving on Citalopram

While on Citalopram, it is important to abstain from alcohol and substance abuse. Concurrent use can intensify the drowsiness and sedation caused by Citalopram, increasing the risk of road accidents.

If you experience sedation or drowsiness after taking Citalopram, it is advisable to seek an alternative mode of transportation, like using public transit or walking, to prioritize road safety.

Conclusion

In this article, we have discussed the potential side effects of Citalopram that can impair driving in certain individuals. We have also explored some management strategies that would avoid road accidents while taking Citalopram.

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References

1.-

 

Sharbaf Shoar N, Fariba KA, Padhy RK. Citalopram [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2023 Oct 11]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482222/#article-19573.s5

 

2.-

 

van der Sluiszen NNJJM, Vermeeren A, van Dijken JH, J A E van de Loo A, Veldstra JL, de Waard D, et al. Driving performance and neurocognitive skills of long-term users of sedating antidepressants. Human Psychopharmacology [Internet]. 2021 Jan 1 [cited 2023 Oct 11];36(1):1–12. Available from: https://pubmed.ncbi.nlm.nih.gov/33001492

 

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Hetland A, Carr DB. Medications and Impaired Driving. Annals of Pharmacotherapy [Internet]. 2014 Jan 28 [cited 2023 Oct 11];48(4):494–506. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965581/

 

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Nader P, Coralie L, Baleydier B, Andrei C, Susanne M, Damsa C. Restless legs syndrome induced by citalopram: a psychiatric emergency? General Hospital Psychiatry [Internet]. 2007 Jan [cited 2023 Oct 11];29(1):72–4. Available from: https://pubmed.ncbi.nlm.nih.gov/17189751/

 

5.-

 

Chen F, Larsen MB, Neubauer HA, Sanchez C, Plenge P, Wiborg O. Characterization of an allosteric citalopram-binding site at the serotonin transporter. Journal of Neurochemistry [Internet]. 2005 Jan [cited 2023 Oct 11];92(1):21–8. Available from: https://doi.org/10.1111/j.1471-4159.2004.02835.x

 

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