Does Celexa cause frequent urination? (3+ factors)
In this article, we will discuss whether Celexa (Citalopram) causes frequent urination. We will also discuss some case reports and the overall incidence of this side effect. We will also discuss what you should do if you are experiencing urinary side effects while taking Celexa.
Does Celexa cause frequent urination?
Celexa may cause frequent urination in some individuals. It is listed as a side effect, but it is not considered that common.
Celexa, a selective serotonin reuptake inhibitor, is an antidepressant used to treat mental health conditions like depression and anxiety (1).
Frequent urination is not a typical or common side effect of Celexa (2). There could be other factors that may make some people more sensitive to this side effect or this side effect may not be directly linked to the use of Celexa. In general other antidepressants like Trazodone, Sertraline, etc. may also cause this side effect.
It is important to keep a close eye on your side effects while being treated with antidepressants.
What does research suggest?
There is limited research indicating frequent urination caused by Citalopram. However, there are several studies indicating the urinary issues caused by the use of selective serotonin reuptake inhibitors (SSRIs) in general. These issues are more common in people who are new to Citalopram or antidepressants in general, or people who have underlying urinary problems.
In a research study, it was found that in males the use of specific antidepressants like selective serotonin reuptake inhibitors (SSRIs) is associated with a higher occurrence of overactive bladder (OAB) and more severe OAB symptoms (3).
Another study indicated that Celexa caused a small increase in urethral pressure suggesting that Celexa is unlikely to lower urethral pressure and make stress urinary incontinence (SUI) worsen in women (4).
Another study observed the effects of SSRIs on new users. They found that these medications were linked to an increased risk of urinary incontinence. Compared to those not taking SSRIs, the risk was 1.75 times higher for people on these drugs (5).
For every 1000 patients taking SSRIs, about 14 extra cases of urinary incontinence occur each year. The risk was even higher for elderly patients, with 60 extra cases per 1000 patients per year (5).
These research studies indicate that Citalopram can cause urinary retention. Some people may experience frequent urination as well. Always remember that everyone may not experience these side effects while taking Citalopram.
What factors can contribute to Citalopram-induced urinary problems?
Several patient-specific factors and health conditions can contribute to Citalopram-induced urinary problems. Firstly individual sensitivity can vary; some people may be more prone to experience these side effects than others.
Additionally, underlying health conditions, such as a history of urinary issues or conditions affecting the bladder, may amplify the likelihood of urinary problems with Celexa.
Furthermore, the concurrent use of other medications alongside Celexa can potentially enhance these side effects.
Healthcare providers need to consider these factors when prescribing Celexa to ensure the best possible treatment plan while minimizing unwanted effects on the urinary system.
What to do if Celexa causes urinary problems?
If you are experiencing urinary problems while taking Citalopram, it is important to discuss them with your healthcare provider. They may gradually reduce the medication’s dose to see if that helps alleviate the issue.
However, if Celexa continues to cause urinary problems, your healthcare provider may discontinue the medication gradually. Celexa may take some time to leave your system. Do not discontinue the medication abruptly as it results in withdrawal symptoms.
Always have a conversation with your healthcare provider who can guide you through the process, and potentially switch to a different medication, or explore other suitable treatment options. Always remember not to make any changes to your treatment plan on your own.
In a nutshell, frequent urination is not typically listed as a common side effect of Celexa (Citalopram). However, individual responses to medications can vary, and some people may experience changes in urinary habits while taking Celexa. If you are concerned about urinary symptoms or changes while on Celexa, it’s important to discuss them with your healthcare practitioner, who can assess your specific situation and provide guidance on appropriate management.
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Sharbaf Shoar N, Fariba KA, Padhy RK. Citalopram. [Updated 2021 Dec 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482222/
MFMER (Mayo Foundation for Medical Education and Research). DRG-20062980. Citalopram (Oral route). 1998-2023.https://www.mayoclinic.org/drugs-supplements/citalopram-oral-route/side-effects/drg-20062980
Solmaz V, Albayrak S, Tekatas A, Aksoy D, Gençten Y, İnanır S, Erdemir F. Evaluation of Overactive Bladder in Male Antidepressant Users: A Prospective Study. Int Neurourol J. 2017 Mar 24;21(1):62-67. doi: 10.5213/inj.1732652.326. PMID: 28361516; PMCID: PMC5380822.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380822/
Christoffersen T, Kornholt J, Riis T, Sonne J, Sonne DP, Klarskov N. Effect of single doses of citalopram and reboxetine on urethral pressure: A randomized, double-blind, placebo- and active-controlled three-period crossover study in healthy women. Neurourol Urodyn. 2022 Aug;41(6):1482-1488. doi: 10.1002/nau.24985. Epub 2022 Jun 30. PMID: 35771361; PMCID: PMC9542537.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542537/