Does Ambien raise blood pressure? 

Does Ambien raise blood pressure? 

Ambien may or may not raise your blood pressure. Blood pressure changes are not generally listed as commonly expected side effects. However, the drug can affect people differently as each individual is unique. 

Some people may experience high blood pressure (1), whereas a few others may experience low blood pressure or orthostatic hypotension (sudden drop in blood pressure when you stand up). It is extremely hard to predict the side effects prior to drug use. 

Studies have shown that the geriatric population is the most commonly affected when it comes to the effects of Ambien on blood pressure. It is also indicated that occasional users don’t commonly report any change in their BP, but daily users do. 

Make sure you’re not taking Ambien for longer than your doctor has recommended. If you’re concerned about your blood pressure while you’re on Ambien, talk to your healthcare provider. Ambien can be split in half if your doctor recommends taking half your usual dose.

Incidence of high blood pressure with Ambien

When it comes to the incidence of high blood pressure specifically related to Ambien use, it is not a commonly reported side effect (2,3). High blood pressure, also known as hypertension, is not listed as a frequent adverse reaction associated with Ambien use.

However, it is important to remember that everyone’s body can react differently to medications. While high blood pressure is not commonly reported with Ambien, individual responses may vary.

It’s also important to follow the prescribed dosage and usage instructions provided by your healthcare provider or as indicated on the medication packaging. If you have a history of high blood pressure or any other pre-existing medical conditions, it’s essential to inform your healthcare provider.

What factors can contribute to high blood pressure while taking Ambien?

While high blood pressure is not a commonly reported side effect of Ambien, there are certain factors that can contribute to an increase in blood pressure while taking the medication. Here are some potential factors to consider:

Individual Sensitivity

Each person’s body can react differently to medications, including Ambien. Some individuals may be more sensitive to the effects of the medication, which could potentially lead to changes in blood pressure.

Interactions with Other Medications

If you are taking other medications along with Ambien, there is a possibility of drug interactions. Certain medications, such as antihypertensive medications or other drugs that affect blood pressure, can potentially interact with Ambien and impact blood pressure levels. (4)

It’s important to inform your healthcare provider about all the medications you are taking to ensure they are aware of any potential interactions.

Underlying Health Conditions

If you have pre-existing health conditions, such as cardiovascular disease, kidney problems, or hormonal imbalances, they may contribute to changes in blood pressure while taking Ambien. These underlying conditions can interact with the medication and affect your blood pressure. (5)

Lifestyle Factors

Lifestyle choices, such as diet, exercise, and stress levels, can also influence blood pressure. While Ambien itself may not directly cause high blood pressure, if you have poor lifestyle habits, such as a high-sodium diet, a sedentary lifestyle, or chronic stress, these factors can contribute to elevated blood pressure levels. (5)

What to do if your blood pressure raises while taking Ambien?

If you notice that your blood pressure is increasing while taking Ambien, it’s important to reach out to your healthcare provider. Keep track of your blood pressure regularly at home using a blood pressure monitor. This will help you understand your blood pressure patterns and identify any changes.

Depending on your individual circumstances, your healthcare provider may recommend adjusting the dosage of Ambien or exploring alternative treatment options.

They may also evaluate other factors that could be contributing to the increase in blood pressure and suggest appropriate management strategies. Adopting a healthy lifestyle can positively impact your blood pressure. (6)

Keep in touch with your healthcare provider for regular check-ups and monitoring of your blood pressure. This will allow them to assess the effectiveness of any adjustments made to your medication or lifestyle and make further recommendations as needed.

Final words

To sum up, Ambien is not commonly associated with blood pressure changes, however, some people may experience changes in their blood pressure while being treated with Ambien.

For such individuals, it’s best to discuss your side effects with your healthcare provider to ensure the safe and effective use of Ambien. If it is not the right choice of medication for you, your doctor will safely switch you to another one.

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McCann CC, Quera-Salva MA, Boudet J, Frisk M, Barthouil P, Borderies P, Meyer P. Effect of zolpidem during sleep on ventilation and cardiovascular variables in normal subjects. Fundam Clin Pharmacol. 1993;7(6):305-10. doi: 10.1111/j.1472-8206.1993.tb00244.x. PMID: 8406294.


Bouchette D, Akhondi H, Quick J. Zolpidem. 2022 Oct 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 28723037.


Edinoff AN, Wu N, Ghaffar YT, Prejean R, Gremillion R, Cogburn M, Chami AA, Kaye AM, Kaye AD. Zolpidem: Efficacy and Side Effects for Insomnia. Health Psychol Res. 2021 Jun 18;9(1):24927. doi: 10.52965/001c.24927. PMID: 34746488; PMCID: PMC8567759.


PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 5732, Zolpidem; [cited 2023 July 13]. Available from:


Oparil S, Acelajado MC, Bakris GL, Berlowitz DR, Cífková R, Dominiczak AF, Grassi G, Jordan J, Poulter NR, Rodgers A, Whelton PK. Hypertension. Nat Rev Dis Primers. 2018 Mar 22;4:18014. doi: 10.1038/nrdp.2018.14. PMID: 29565029; PMCID: PMC6477925.


Campbell NR, Burgess E, Choi BC, Taylor G, Wilson E, Cléroux J, Fodor JG, Leiter LA, Spence D. Methods and an overview of the Canadian recommendations. Canadian Hypertension Society, Canadian Coalition for High Blood Pressure Prevention and Control, Laboratory Centre for Disease Control at Health Canada, Heart and Stroke Foundation of Canada. CMAJ. 1999 May 4;160(9 Suppl):S1-6. PMID: 10333847; PMCID: PMC1230333.