Can Cymbalta get you high? 

Can Cymbalta get you high? 

No, Cymbalta (Duloxetine) can not get you high. It is a non-narcotic antidepressant which is not considered a drug of abuse or a controlled substance. 

However, Cymbalta is still misused because of its mood-boosting effects, but that doesn’t last very long. Consistent high doses of Cymbalta can cause a number of disturbing side effects, which can lead to life-threatening complications. 

So no, Cymbalta does not get you high or induce euphoria. Make sure you only take the right amount of medication – that your doctor has prescribed. Misusing antidepressants can be your biggest nightmare and can cause dreadful consequences. 

How is Cymbalta different from the medications that get you high?

Cymbalta is an antidepressant, which belongs to the class of serotonin-norepinephrine reuptake inhibitors (SNRIs). These antidepressants inhibit the reuptake of two monoamine excitatory chemicals – serotonin and norepinephrine (1). 

This enhances your brain activity and helps you with symptoms associated with depression, anxiety, and several other mental health conditions. Cymbalta is different from medications that get you high because it does not produce a euphoric or intoxicating effect when taken as prescribed. 

Can Cymbalta affect your health?

Although it doesn’t get you high, Cymbalta is associated with some side effects. These include:

  • Nausea 
  • Vomiting
  • Diarrhoea or Constipation
  • Acid reflux or heartburn
  • Abdominal pain 
  • Bloating 
  • Weight-related changes 
  • Dry mouth 
  • Increased appetite or loss of appetite 
  • Frequent urination 
  • Night sweats and excessive sweating in general 
  • Headache 
  • Confusion 
  • Dizziness 
  • Drowsiness
  • Insomnia 
  • Forgetfulness 
  • Muscle pain 
  • Sexual side effects in both men and women 

Make sure you properly monitor your side effects while being treated with Cymbalta and report them to your healthcare provider. Cymbalta can cause psychological side effects in some people, especially those who may have an undiagnosed mental disorder and those with excessive alcohol consumption with Cymbalta.

This is why it’s extremely important to consult your doctor in case you are struggling with psychological side effects on Cymbalta. It is also important to take this antidepressant just as directed by your doctor.

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PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 60835, Duloxetine; [cited 2023 Jan 31]. Available from:

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