Does Pepcid help diarrhoea? 

Does Pepcid help diarrhoea? 

Pepcid (Famotidine) does not help diarrhoea that much, as it’s more focused on managing your stomach acidity. Pepcid is an H2-receptor antagonist that inhibits the secretion of gastric acid in your stomach, to protect the lining of your stomach from the corrosive effects of the acid (1). 

Diarrhoea is caused by increased gastrointestinal motility, and it can not be controlled by Pepcid. Make sure you take the right medication for diarrhoea when using OTCs or reach out to your healthcare provider for better management of your diarrhoea. 

Unmanaged diarrhoea can lead to dehydration and extreme weakness, which may result in hospitalisation. In general, medications that control acid reflux (like Pepcid), nausea (antiemetics and antihistamines like Phenergan), etc can not manage diarrhoea effectively.

What medications treat diarrhoea? 

Antidiarrheal medications are used for the management and treatment of diarrhoea. Imodium (Loperamide) is the most commonly used antidiarrheal medication and provides promising results (2).  

Other medications like Pepto-Bismol (Bismuth subsalicylate) can also be used for the management of diarrhoea. Probiotics are also used along with antidiarrheal meds to replenish the good gut bacteria. However, some diarrhoea is associated with a bacterial infection. 

Such diarrhoea can not be treated without the use of antibiotics and they are generally more painful and uncontrollable than general diarrhoea. 

When to seek medical attention

Mild diarrhoea is usually nothing to worry about and it does get resolved with the help of OTC medications and a soft diet. However, if your diarrhoea is paired with fever and chills, or if you observe streaks of food in your stools or a reddish hue, you should seek immediate medical attention. 

As I mentioned earlier, some diarrhoea is infectious and they can affect your health if not managed properly. Severe and untreated diarrhoea can significantly dehydrate you and can lead to hospitalisation. It could take a life-threatening turn, especially in the case of children and elderly individuals. 

This is why it’s important to consult your doctor if you, your child, or someone you care for has diarrhoea which does not get better or is uncontrollable. It is also important to stick to a light diet and PLENTY of fluids to make for dehydration. 

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MedlinePlus. Famotidine [Internet]. Bethesda (MD): National Library of Medicine (US); [updated 2022 Apr 15; cited 2022 Feb 15]. Available from:


National Health Service (NHS). Loperamide: a medicine used to treat diarrhoea [Internet]. NHS.UK. 2021 [cited 2022 Feb 15]. Available from: