Does Luvox cause nausea? (5+ management tips)

In this article, we will discuss the possibility of nausea being caused by Luvox. We will also highlight the causes and management techniques to overcome nausea caused by Luvox.

Does Luvox cause nausea?

Yes, nausea is a side effect of Luvox (fluvoxamine). It is one of the common symptoms associated with Luvox which is often accompanied by vomiting. It is to be noted that not all individuals taking Luvox experience this side effect. (1)

Luvox (fluvoxamine) is an antidepressant belonging to the class of selective serotonin reuptake inhibitor (SSRI) and is used for the treatment of depression and obsessive-compulsive disorder. Gastrointestinal side effects such as nausea and vomiting are very common among this class of antidepressants.

How does Luvox cause nausea?

It has been recently suggested that serotonin might be the key player in fluvoxamine-induced nausea. Fluvoxamine activates 5-HT3 receptors located at the visceral afferent fibres which are connected to the vomiting centre. The activation of these receptors leads to nausea which is often accompanied by vomiting.

To overcome this, research has suggested that fluvoxamine should be started at a low dose of 50 mg per day and gradually increased to the required dosage throughout the treatment. (2)

What does research suggest?

There is scientific literature and research available to support the fact that fluvoxamine is responsible for causing nausea. It is one of the common side effects of this medication. 

According to research, 15 to 40% of cases have reported that they experienced fluvoxamine-induced nausea. (2)

One study highlighted that nausea was reported by over one-third of the participants taking fluvoxamine but the symptoms ameliorated after two weeks of medication. This showcases that nausea can be a temporary side effect experienced by some individuals at the start of the treatment. (3)

What are the management tips for fluvoxamine-induced nausea?

Consultation with a healthcare provider: In case of severe or persistent nausea or nausea being bothersome, consultation with the healthcare provider is recommended. They can adjust the dosage on a case-by-case basis. If that is not possible, they will share alternative treatment plans to try to accommodate your concerns.

Home remedies: In normal circumstances, nausea usually goes away within the first two or three weeks. During this time, home remedies such as ginger, peppermint or lemon in the form of tea can be ingested for relief.

Over-the-counter (OTC) medications: Medications such as Pepto-Bismol and Kaopectate may help alleviate the symptoms. It is highly recommended to inform healthcare professionals before using any other medications apart from the ones prescribed by the doctor.

Dietary adjustments: Avoid having big meals and switch to smaller but more frequent meals. This will help the stomach to digest and process food more quickly and efficiently and reduce the chances of nausea.

Lifestyle adjustments:

  • Incorporating regular exercise within daily lifestyle helps promote the immune and gastrointestinal systems to work more efficiently.
  • Try maintaining a stress-free routine or indulge in meditation or yoga to release the stress and anxiety. Stress and anxiety can also contribute to nausea.
  • Avoid strong odours that are triggering the nausea. The type of odour depends on the individual and is not specific to one person.

What are the common side effects of Luvox?

Some of the common side effects caused by Luvox are listed below: (1)

Gastrointestinal symptoms:

  • Nausea
  • Vomiting
  • Anorexia
  • Constipation
  • Dyspepsia
  • Diarrhoea

Central nervous symptoms:

  • Somnolence
  • Insomnia
  • Dry mouth
  • Nervousness
  • Tremor and agitation
  • Asthenia

Abnormal ejaculation:

  • Mostly delayed ejaculation is observed

Are there alternatives to Luvox that do not cause nausea?

There are some medications available that do not cause nausea and can be used instead of Luvox. Most of the medications have nausea as a common side effect. Therefore, consultation with the healthcare provider is very important to decide which medication is best suited to you.

Alternative options would include the choice of drug from the same class i.e. serotonin and norepinephrine reuptake inhibitors (SNRI) or selective serotonin reuptake inhibitors (SSRI). Different drugs will have different side effect profiles. Therefore, the risk-benefit profile needs to be carefully examined before prescription.

Prozac (fluoxetine) belongs to the class of selective serotonin reuptake inhibitor (SSRI) and can be used as an alternative to venlafaxine. It has been known to not cause nausea and is indicated for the treatment of major depressive disorder, panic disorder, obsessive-compulsive disorder, bulimia nervosa and premenstrual dysphoric disorder. 


In my opinion, most of the medications have nausea listed as a side effect. The benefits over risk ratio need to be evaluated before making any decisions. Luvox causes nausea but it can be managed through dose adjustment or other remedies listed above. 

Was this helpful?

Thanks for your feedback!



Nobuhisa Ueda, Reiji Yoshimura, Koji Shinkai, Takeshi Terao, Jun Nakamura, Characteristics of fluvoxamine-induced nausea, Psychiatry Research, Volume 104, Issue 3, 2001, Pages 259-264, ISSN 0165-1781.


BURTON, STEPHEN W.. A Review of Fluvoxamine and its Uses in Depression. International Clinical Psychopharmacology 6():p 1-22, December 1991.

Find a supportive therapist who can help with Depression.

Discover the convenience of BetterHelp, an online therapy platform connecting you with licensed and accredited therapists specialized in addressing issues such as depression, anxiety, relationships, and more. Complete the assessment and find your ideal therapist within just 48 hours.


AskYourPharm is user-supported. We may earn a commission if you sign up for BetterHelp’s services after clicking through from this site