Does generic Pristiq cause weight gain? (+3 tips)

In this article, we will discuss whether generic Pristiq causes weight gain. We will also discuss some research studies and what one should do if this side effect occurs.

Does generic Pristiq cause weight gain?

Yes, generic Pristiq, also known as Desvenlafaxine, can cause weight gain. Pristiq is the brand name, but there are various generic versions of Desvenlafaxine available and approved by regulators.

Generic versions have the same active ingredient but may have different excipients or fillers, which can affect how they work in the body. However, they are all considered to be just as active as the brand name Pristiq.

Weight gain is a possible side effect associated with many antidepressant medications, including Pristiq and its generic counterparts (1). However, the extent of weight gain can vary from person to person and not everyone experiences this side effect.

Make sure you consult your healthcare provider if you experience Pristiq-induced weight gain.

What does research suggest?

There is limited research indicating weight gain due to generic Pristiq. One research indicated that in short-term studies with about 1800 people, the drug Desvenlafaxine led to a small but noticeable decrease in weight compared to those taking a Placebo (2).

During a 12-week follow-up with about 600 people both the drug and placebo caused a small increase in overall weight (2).

Another research stated that certain pathways related to serotonin and histamine might cause weight gain as a side effect of some antidepressants in general. So when choosing antidepressants, it is important to think about how they might affect weight and try to control any unwanted weight changes (3).

People respond differently to medications. Some people may experience weight loss as a side effect of Pristiq. Reach out to your healthcare provider if you are experiencing weight changes while on Pristiq (4).

What is the controversy about generic Pristiq?

The controversy surrounding generic versions of Pristiq has been a concern. Some people wonder if generic versions are as good as brand, while others talk about how much they cost.

Regulatory bodies make sure generic drugs are safe and work well, but some people still like the brand better because they think it works differently.

It is important to talk to a healthcare provider about any worries with generic medications to choose the best treatment.

How to ensure the safety and quality of generic Pristiq?

Ensuring the safety and quality of generic Pristiq is essential. The FDA mandated that generic drugs must meet the same standards for safety, effectiveness, and quality as their brand-name counterparts.

Generic Pristiq is subject to bioequivalence testing to guarantee that it is therapeutically equivalent to the brand name drug, assuring its effectiveness. You should trust the regulatory authority here.

It is also advisable to obtain generic drugs from trustworthy sources to ensure product quality and safety.

What to do if generic Pristiq makes you gain weight?

If you suspect Pristiq is making you gain weight, you should take the following steps:

Consulting your doctor

Talk to your doctor promptly, they will assess your condition and determine whether weight gain is due to Pristiq or any other reason. There are a huge number of antidepressants available because one medication does not work well for every other individual.

If you are gaining weight on Pristiq, this indicates that it is not the right choice of antidepressant for you. If that’s the case your doctor may switch to another antidepressant with a lower potential for weight gain.

Eating habits

Being mindful of your eating habits is crucial if you are experiencing weight gain due to antidepressants. The medication might trigger emotional cravings, but you must fight through them and make good food choices. This can make you feel satisfied without causing substantial weight gain.

Lifestyle modification

It is important to exercise every day, especially if you are gaining weight. Even if you are not sure why you are gaining weight, exercise can really help you lose it. It can also reduce your depression and anxiety by releasing good chemicals in your brain, which can help with feelings of sadness or worry.

Try fasting

Intermittent fasting is a safe and helpful way to lose weight. In fasting, you don’t have to change what you eat, but you do need to eat during specific times which helps in reducing your weight.

In my view, generic Pristiq can cause weight gain. However, individual responses to medications vary. Always consult your healthcare provider about antidepressant use to ensure its safety and efficacy.


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