Does drowsiness from Effexor go away? (3+ factors)

In this article, we will discuss whether Effexor-induced drowsiness goes away. We will also discuss some research studies, and factors influencing drowsiness while taking Effexor.

Does drowsiness from Effexor go away?

Yes, Effexor (Venlafaxine) induced drowsiness does start to get better with time, as your body adjusts to the medication. Drowsiness is quite common in new users and around 20-30 % of people report this side effect.

Drowsiness associated with Effexor will gradually improve within the first few weeks of starting the medication. However, it is essential to remember that everyone’s response to medications differs, and some patients may experience drowsiness for extended periods (1).

Moreover, individual factors such as dosage, overall health, and metabolism can influence how long the drowsiness persists. Patience is necessary while adjusting to Effexor, and it is advisable to consult a healthcare professional if the drowsiness becomes bothersome or remains for an extended duration.

What does research suggest?

Research reveals that antidepressants have a significant impact on sleep patterns, including the specific alteration of rapid eye movement (REM) sleep. These changes lead to shorter duration and delayed onset of REM sleep (2,3).

As a consequence, individuals may encounter difficulties falling asleep, experience disturbed sleep patterns, and observe a reduction in overall REM sleep time. This can result in inadequate recovery and persistent fatigue and drowsiness throughout the day.

Other antidepressants like Citalopram, Sertraline, etc may also cause drowsiness as an early side effect.

What factors influence Effexor-induced drowsiness?

Several factors can influence the severity and duration of drowsiness caused by Effexor. These factors include:

Dosage: The dosage of Effexor can influence the severity of drowsiness. Higher doses may increase the likelihood and intensity of drowsiness.

Time of administration: Taking Effexor at different times of the day can affect drowsiness. Some individuals find that taking it in the morning minimizes drowsiness because it has time to wear off throughout the day. Others may need it take it at night to avoid daytime drowsiness.

Age: Elderly individuals may be more prone to experience drowsiness as a side effect of Effexor.

Underlying medical condition: Individuals with underlying health conditions and existing sleep disorders, like obstructive sleep apnea, and chronic sleep deprivation may be more likely to experience drowsiness.

Drug interactions: The interaction of Effexor with other medications can potentially enhance drowsiness like sedatives, first-generation antihistamines, opioids etc.

It is important to inform your healthcare provider about any other medications, herbal supplements, or substances you are taking to minimise the risk of drug interactions.

How to manage Effexor-induced drowsiness?

Several approaches can be used to manage Effexor-induced drowsiness. It is crucial to consult with your healthcare professional before changing your medication or treatment regimen. They can provide personalized advice, assess your specific situation and provide you with the best strategies to effectively manage Effexor-induced drowsiness (4).

Dose adjustment

Your doctor may initially adjust your dosage to see if it works for you. By lowering the antidepressant dose, side effects like drowsiness may subside. However, if dose reduction does not work your, doctor may gradually discontinue your medication or may switch to another medication with fewer side effects.

Time adjustment

Modifying the timing of when you take Effexor may help alleviate drowsiness. Your healthcare professional can guide the optimal dosing schedule. In some cases, your doctor may recommend adding a medication specifically targeted to counteract drowsiness (4).

These include: 

• Modafinil
• Bupropion
• Protriptyline
• Amphetamines

Lifestyle modification

Prioritize adequate and high-quality sleep. Ensure a consistent sleep schedule, create a bedtime routine and optimize your sleep environment to promote quality rest.

Develop good sleep hygiene practices, such as avoiding caffeine or stimulating activities close to bedtime, keeping your bedroom dark and creating a relaxing pre-sleep routine. It is also recommended to engage in regular exercise, as it can boost energy levels and improve daytime alertness.

Be aware of substances that can worsen drowsiness, such as alcohol sedatives or certain over-the-counter medications. Limit their use or avoid them entirely to help manage Effexor-induced drowsiness.

Conclusion

In my view and the information available drowsiness caused by Effexor typically improves within the first few weeks of starting the medication. However, the duration can vary from person to person.

It is important to consult with a healthcare professional before making any changes to the medication. They can guide you to the best strategies to effectively manage Effexor-induced drowsiness.

References