Does Celebrex expire? 

In this brief article, we will address whether Celebrex expires, along with other considerations such as the usability of this expired medication, the dangers associated with expired Celebrex, what to do if you have consumed expired Celebrex, the potential adverse effects of Celebrex, how to identify spoiled Celebrex, and proper storage of this medication. 

Celebrex is a prescription non-steroidal anti-inflammatory drug that has an expiration date, and its use beyond that date is not recommended (1,2,3).

No one can definitively state the potential health risks associated with the use of expired Celebrex (4,5). 

If you have accidentally consumed expired Celebrex, remain vigilant for symptoms and seek medical attention if you experience any severe adverse effects (2,3).

Keep Celebrex in its original container in a well-ventilated area. Spoiled medications may exhibit changes in visual characteristics and have a strong odor. 

If you notice any apparent changes in the characteristics of Celebrex, do not take the medication (6,7).

Does Celebrex expire? 

Yes, Celebrex does expire like every other medication, and the Food and Drug Administration (FDA) strongly advised against taking expired drugs (1). Can you use expired Celebrex?

This is not an appropriate practice, not only because the drug has expired, but also because Celebrex is a prescription non-steroidal anti-inflammatory drug (NSAID) and you shouldn’t take it without your doctor’s approval (2,3).

Although some drugs may retain their effectiveness for an extended duration, beyond their expiration date, the use of expired medications is not recommended.

Improper storage conditions can accelerate the degradation process of medications. Moreover, all expired drugs are  bound to lose their potency sooner or later, and their safety cannot be guaranteed.

For this reason, the FDA strongly discourages the consumption of any expired medication (1,4).

So, it’s best to avoid expired Celebrex or any other medication for that matter. If you think you need this medication, it’s best to reach out to your provider and get a new prescription. 

What are the dangers associated with the use of expired Celebrex? 

Although expired Celebrex may not pose a health risk if expired recently, it should not be taken.

There is no research data available regarding the safety and efficacy of expired Celebrex and no one can say for sure what potential health risks are associated with their use, not even the manufacturers. 

That’s the entire point of printing expiry dates on the packaging, as the manufacturers can’t guarantee the effectiveness and safety of their medications past the expiration dates (1,5). 

It’s Important to consider that Celecoxib, being a NSAID, can be utilized for various health conditions. Inadequate therapeutic response can result in treatment failure, and the desired outcomes may not be achieved (2,3). 

Always remember, proper use of medications is the key to achieving the most out of them. 

What to do if you have taken expired Celebrex? 

If you have taken expired Celebrex, please remain vigilant for symptoms and seek medical attention if you experience any unusual issues (2,3).

As a general rule of thumb, you shouldn’t take expired medications, as you never know what side effects they might end up causing (2,6).

It’s best to replace the expired Celebrex with a new one. 

What adverse effects may Celebrex cause?

Celebrex may be associated with the following adverse effects (2,3):

  • Gas or bloating
  • Sore throat
  • Cold symptoms
  • Constipation
  • Dizziness
  • Dysgeusia

Some side effects can be serious, such as:

  • Unexplained weight gain
  • Shortness of breath or difficulty breathing
  • Swelling of the abdomen, feet, ankles, or lower legs
  • Diarrhea
  • Nausea
  • Excessive tiredness
  • Unusual bleeding or bruising
  • Itching
  • Lack of energy
  • Loss of appetite
  • Pain in the upper right part of the stomach
  • Yellowing of the skin or eyes
  • Flu-like symptoms
  • Blisters
  • Fever
  • Rash
  • Hives
  • Swelling of the face, throat, tongue, lips, eyes, or hands
  • Hoarseness
  • Difficulty swallowing or breathing
  • Pale skin
  • Fast heartbeat
  • Cloudy, discolored, or bloody urine
  • Back pain
  • Difficult or painful urination
  • Frequent urination, especially at night

Talk to your doctor if you experience any unusual or persistent problems while taking this medication.

If you experience any of the following symptoms, stop taking Celebrex and call your doctor: stomach pain, heartburn, vomiting a substance that is bloody or looks like coffee grounds, blood in the stool, or black and tarry stools (2).

Additionally, it’s important to know that NSAIDs, such as Celebrex, cause an increased risk of serious cardiovascular thrombotic events, as well as serious gastrointestinal adverse events, which can be fatal (3).

How to identify spoiled Celebrex?

Some characteristics can indicate that a medication is spoiled, such as (6,7):

  • packaging integrity: If a package is open or tampered with, with the medication exposed to the environment, there is a high chance of medication deterioration
  • visible signs of deterioration: Discoloration, damage caused by moisture, damage caused by fungi or bacteria, or any other apparent modification of the medication.
  • strong and unusual odor.

How should Celebrex be properly stored?

Please store this medication in its original container, tightly closed, and keep it at room temperature, away from excessive heat and moisture (avoid storing it in the bathroom). 

It is absolutely essential to keep all medications out of sight and reach of children, as some containers may not be child-resistant (2,3).

Conclusion

In this brief article, we have addressed whether Celebrex expires, along with other considerations such as the usability of this expired medication, the dangers associated with expired Celebrex, what to do if you have consumed expired Celebrex, the potential adverse effects of Celebrex, how to identify spoiled Celebrex, and proper storage of this medication. 

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References

1.-

U.S. Food and Drug Administration. Don’t Be Tempted to Use Expired Medicines [Internet]. Silver Spring (MD): U.S. Food and Drug Administration; 2021 [cited 2023 Jun 26]. Available from: https://www.fda.gov/drugs/special-features/dont-be-tempted-use-expired-medicines.

2.-

CELEBREX® (celecoxib).  U.S. Food and Drug Administration. Reference ID: 3517626 [Internet] [updated 2017 Jun; cited 2023 Jun 27]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/020998s056lbl.pdf.

3.-

MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); c1998–2023. Celecoxib; [updated 2022 Oct 15; cited 2023 Jun 27]. Available from: https://medlineplus.gov/druginfo/meds/a699022.html.

4.-

Gikonyo D, Gikonyo A, Luvayo D, Ponoth P. Drug expiry debate: the myth and the reality. Afr Health Sci. 2019;19(3):2737-2739.

5.-

JAMA Network. Drugs Past Their Expiration Date. JAMA. 2016;315(5):510–511.

6.-

World Health Organization. Guidelines for the safe disposal of expired drugs [Internet] [updated 2006 May 17; cited 2023 Jun 27]. Available from: http://www.emro.who.int/images/stories/pakistan/documents/pak_documents/Guidelines_for_Expired_Medicines.pdf.

7.-

U.S. Food and Drug Administration. ICH quality guidelines [Internet] [updated 2018 Jul 13; cited 2023 Jun 27]. Available from: https://www.fda.gov/drugs/guidances-drugs/international-council-harmonisation-quality.