Does Baclofen show up on a drug test? 

Does Baclofen show up on a drug test? 

No, Baclofen does not show up on a drug test and it does not cause false-positive test results. Baclofen is a prescription medication used to manage muscle spasms (1). 

This medication does not cause any sort of addiction and it is not included in the category of controlled substances. However, some urine drug tests may end up showing a false positive because of their impaired accuracy. 

If such a test shows a false positive result, it’s best to go for more sensitive testing procedures like Gas Chromatography – Mass spectroscopy (GC-MS), which provide more promising test results (2). 

Common substances detected in drug tests

Common drugs which are detected in a drug test include (3,4):

  • Marijuana: This is a commonly tested substance, and it includes THC (tetrahydrocannabinol), which is the main psychoactive compound found in Cannabis.
  • Cocaine: Drug tests can detect the presence of Cocaine, which is a stimulant drug that can produce feelings of euphoria and increased energy.
  • Opioids: This category includes drugs like Heroin, Morphine, Codeine, and prescription pain medications such as Oxycodone and Hydrocodone.
  • Amphetamines: These drugs, including medications like Adderall and Methamphetamine, are stimulants that can enhance focus and energy.
  • Benzodiazepines: Commonly prescribed medications for anxiety or sleep disorders, such as Xanax, Klonopin and Valium, fall into this category.
  • Barbiturates: These are sedative drugs that were once commonly prescribed for anxiety or insomnia but are now less frequently used.
  • Phencyclidine (PCP): PCP is a hallucinogenic drug that can cause altered perceptions and behaviour.
  • Methamphetamine: Also known as meth, this is a potent stimulant drug that can have severe effects on the body and mind.
  • MDMA (Ecstasy): This is a party drug known for its hallucinogenic and stimulant effects.

Final words

To sum up, Baclofen is not detected in a drug test, as it doesn’t belong to any class of medications that commonly show up on drug tests. Baclofen is also not known to cause a false positive for any such substance (5). So don’t worry, this medication will not make you fail a drug test.

However, Baclofen may cause some side effects, so it is important to use this medication properly. It is also important to stick to the recommended dose and not use it more often than you should. Always check for drug expiry before you use any medication to ensure its safety and potency.

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Ghanavatian S, Derian A. Baclofen. 2022 Dec 11. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 30252293.


Ramoo B, Funke M, Frazee C, Garg U. Comprehensive Urine Drug Screen by Gas Chromatography/Mass Spectrometry (GC/MS). Methods Mol Biol. 2016;1383:125-31. doi: 10.1007/978-1-4939-3252-8_15. PMID: 26660182.


McNeil SE, Chen RJ, Cogburn M. Drug Testing. 2023 Jan 16. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 29083751.


Moeller KE, Lee KC, Kissack JC. Urine drug screening: practical guide for clinicians. Mayo Clin Proc. 2008 Jan;83(1):66-76. doi: 10.4065/83.1.66. Erratum in: Mayo Clin Proc. 2008 Jul;83(7):851. PMID: 18174009.


Alyson Schwebach, Jennifer Ball. Urine Drug Screening: Minimizing False Positives and False Negatives to Optimize Patient Care. US Pharm. 2013;38(12):1-6. Available at: