Does Amlodipine Cause Constipation? (5 things to do)

Does Amlodipine Cause Constipation?

Yes, Amlodipine can cause constipation in some patients. Although it is not a commonly reported side effect of Amlodipine (1), it can still occur in certain individuals. Amlodipine is used to treat high blood pressure(hypertension) and chest pain(angina).

As medicines for chronic health conditions like hypertension, diabetes, asthma, or any such issues are meant to be used for a prolonged period, These medicines should not be randomly discontinued unless prescribed by your physician.

If you are experiencing constipation while taking Amlodipine, consult your healthcare provider. They can evaluate your symptoms, consider other potential causes, and determine the most appropriate action. It’s important not to change your medication regimen without consulting a healthcare professional.

What does the research indicate?

A study on intestinal obstruction caused by Amlodipine overuse in a 60 years old female was published in QJM, International Journal of Medicine, in 2012. The study concluded after extensive research that severe acute intestinal obstruction should be included in the list of gastrointestinal side effects from Amlodipine. (2)

Although not mentioned in the drug resources, severe acute intestinal obstruction is a serious complication and, if untreated, can lead to intoxication and, ultimately, can prove to be life-threatening.

What can you do if you experience constipation while taking Amlodipine?

If you experience constipation while taking Amlodipine, there are several steps you can take:

  • Stay hydrated: Drink adequate water throughout the day to maintain hydration. Sufficient hydration can help soften stools and facilitate bowel movements.
  • Increase fiber intake: Consume a fiber-rich diet from fruits, vegetables, whole grains, and legumes. Fiber helps regulate bowel movements.
  • Engage in physical activity: Regular exercise or physical activity can help stimulate bowel movements and alleviate constipation. Do moderate exercise at least three days a week.
  • Consider over-the-counter remedies: Talk to your pharmacist or healthcare provider about options such as fiber supplements or mild laxatives that may help relieve constipation.
  • Communicate with your healthcare provider: If constipation persists or becomes bothersome, discussing it with your healthcare provider is recommended. They may suggest adjustments to your medication dosage or recommend alternative treatment options.

Remember, it’s crucial to consult your healthcare provider before changing your medication regimen or starting any new treatments.

When should you consult your doctor?

If you are experiencing abdominal discomfort while taking Amlodipine and are worried it might cause serious issues, you should immediately consult your doctor.

Leaving constipation untreated for a long time can have harmful effects on your anal muscles leading to severe medical conditions like Anal Fissures, Hemorrhoids, Fecal Impaction, and in rare cases, it might result in Intestinal Perforation through a tare which can cause lethal infection.

Hypertensive medications, like Amlodipine, are for prolonged use, for a lifetime in most cases. Abrupt discontinuation of these medicines is not safe. If Amlodipine is causing constipation, your doctor will prescribe a suitable change to your prescription, or a decreased dose may be prescribed. Amlodipine can be split in half, so you might not need a prescription refill.


In conclusion, Amlodipine can cause constipation in some patients, although it is not a commonly reported side effect. If you experience constipation while taking the drug, it is essential to consult your healthcare provider for evaluation and guidance.

Taking certain steps, such as staying hydrated, increasing fiber intake, engaging in physical activity, and considering over-the-counter remedies, may help alleviate constipation. You must consult your healthcare professional before changing your medication and stick to your regular dosing schedule until your next appointment with your doctor.

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Amlodipine (National Library of Medicine, NIH)


Intestinal obstruction secondary to amlodipine toxicity (QJM, International Journal of Medicine, 2012)