Can you take Tylenol or Advil with Amoxicillin?
By
Dr Drielli Vital-Fujii (PhD)
Author bio
Dr Drielli Vital-Fujii, PhD, is a Pharmacist with expertise in Drug Design and Development, Enzymes, Molecular Modelling, and Photodynamic Therapy. She writes and reviews content on these topics.
Dr Drielli Vital-Fujii’s Highlights:
- Postdoctoral fellow at the Department of Biochemistry at the University of São Paulo, emphasizing therapy of neglected diseases using light.
- PhD in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Six months as an international researcher at the Center for Discovery and Innovation in Parasitic Diseases (University of California San Diego)
- Master’s degree in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Bachelor of Pharmacy at the University of Mogi das Cruzes – São Paulo / Brazil
Professional Experience:
2012 – 2018 Project manager at University of São Paulo – Pharmacy Department
Dr Drielli Vital-Fujii has worked with computational studies, synthesis, biological evaluation, design, and development of new inhibitor candidates for Chagas Disease and Leishmaniasis.
2017 – 2017 International research fellow at University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences – Center for Discovery and Innovation in Parasitic Diseases.
She used Virtual Screening (VS) and High-Throughput Screening (HTS) Integration in the Discovery of new drugs against neglected tropical diseases (NTDs).
2018 – 2019 Faculdades Oswaldo Cruz
Dr Drielli Vital-Fujii was a professor in the Faculty of Pharmacy, teaching the subjects of Pharmaceutical Chemistry and Drug Development.
2019 – 2021 Researcher in Biochemistry University of São Paulo – Biochemistry Department
She applied Photodynamic Therapy in Leishmaniasis Treatment, mentored undergraduate students in scientific activities, and wrote, executed, translated, and reported scientific projects with funding agencies.
2023-2023 UniPiaget – University Center.
Dr Drielli Vital-Fujii was a Biology, Nutrition, Physiotherapy, and Pharmacy professor.
Education:
2018 -2021 Postdoctoral at the Department of Biochemistry at the University of São Paulo
2013 -2018 PhD of Science: Drugs and Medicines at Department of Pharmacy at University of São Paulo
2012 -2013 M.Sc. of Sciences: Drugs and Medicines at the Department of Pharmacy at the University of São Paulo
2005-2008 Bachelor of Pharmacy at the University of Mogi das Cruzes
The leading publications of Dr Drielli Vital-Fujii are:
Vital-Fujii, D.G, Baptista, M.S. (2021). Progress in the photodynamic therapy treatment of Leishmaniasis. Brazilian Journal of Medical and Biological Research, 54, 1-11.
Gatti, F. M., Gomes, R.A., da Fonseca, A.L., Lima, E.J.C., Vital-Fujii, D.G., Taranto, A.G., Varotti, F.P., Trossini, G.H.G. (2020). Antiplasmodial activity of sulfonylhydrazones: in vitro and in silico approaches. Future medicinal chemistry, 13, 233-250.
Silva, E.J., Bezerra-Souza, A., Passero, L.F., Laurenti, M.D., Ferreira, G.M., Fujii, D.G.V., et al. (2018). Synthesis, leishmanicidal activity, structural descriptors and structure-activity relationship of quinoline derivatives. Future medicinal chemistry, 10, 2069-2085.
Leite, F.H.A., Froes, T.Q., da Silva, S.G., de Souza, E.I.M., Vital-Fuji,i D.G., Trossini, G.H.G., et al. (2017). An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors. European Journal of Medicinal Chemistry, 132, 322-332.
Vital, D.G., Damasceno, F.S., Rapado, L.N., Silber, A.M., Vilella, F.S., Ferreira, R.S., et al. (2017). Application of bioisosterism in design of the semicarbazone derivatives as cruzain inhibitors: a theoretical and experimental study. Journal of Biomolecular Structure and Dynamics, 35, 1244–1259.
Mello, J. F.R., Gomes, R.A., Vital-Fujii, D.G., Ferreira, G.M., Trossini, G.H.G. (2017). Fragment-based drug discovery as alternative strategy to the drug development for neglected diseases. Chemical Biology & Drug Design, 90, 1067-1078.
Pantaleao, S.Q., Fujii, D.G.V., Maltarollo, V.G., da C. Silva, D., Trossini, G.H.G., Weber, K.C., et al. (2017). The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery. Medicinal Chemistry, 13, 706-720.
Vital, D., Arribas, M., Trossini, G. (2014). Molecular Modeling and Docking Application to Evaluate Cruzain Inhibitory Activity by Chalcones and Hydrazides. Letters in Drug Design and Discovery, 11, 249-255.
Blau, L., Menegon, R.F., Trossini, G.H.G., Molino, J.V.D., Vital, D.G., Cicarelli, R.M.B., et al. (2013). Design, synthesis and biological evaluation of new aryl thiosemicarbazone as antichagasic candidates. European Journal of Medicinal Chemistry, 67, 142-151.
You can view some of Dr Drielli’s work below and links to her professional profile.
Orcid: https://orcid.org/0000-0001-9270-0466
Research Gate: https://www.researchgate.net/profile/Drielli-Gomes-Vital-Fujii
Scopus: https://www.scopus.com/authid/detail.uri?authorId=55829534000
Google Scholar: https://scholar.google.com/citations?user=F9U50AEAAAAJ&hl=pt-BR
Linkedin: linkedin.com/in/driellivital
Escavador: https://www.escavador.com/sobre/6101380/drielli-gomes-vital
CDIPD: https://cdipd.org/index.php/about-us/visiting-scientists
Can you take Tylenol or Advil with Amoxicillin?
You can take Tylenol or Advil with Amoxicillin as there is no known interaction between these medications. Amoxicillin is a broad-spectrum antibiotic and it is a known fact that infections can cause pain (3).
Such OTC painkillers can be used safely. Let’s break it down a little to help you understand better.
Tylenol with Amoxicillin
Taking Tylenol with Amoxicillin is usual, and there’s nothing wrong with taking them together. In fact, the tablets can be taken at the same time. Tylenol contains Acetaminophen, which is considered one of the safest painkillers (1,3).
It can also help reduce fever that might be present with a bacterial infection as the immune system raises body temperature to help your body fight against the ongoing bacterial infection (1).
Advil with Amoxicillin
Advil can be taken with Amoxicillin. However, antibiotics, including Amoxicillin, may cause gastrointestinal side effects as they also attack healthy gut bacteria along with the infectious ones (2,3). If you find Amoxicillin heavy on your stomach, taking Advil with it may contribute to it.
This is because Advil is a Non-steroidal anti-inflammatory drug and all NSAIDs are associated with gastrointestinal side effects (2). Instead of Advil, you can take Tylenol if your stomach is upset.
How to ensure the proper use of Tylenol or Advil with Amoxicillin?
Some tips to ensure the proper use of Tylenol or Advil with Amoxicillin include:
- Consult your healthcare provider before taking any medication together to avoid potential interactions or side effects. Amoxicillin can cause gastrointestinal side effects which can be prevented by taking the medication with food.
- Follow the prescribed dosages and timing for each medication as directed by your healthcare provider.
- Check the labels of other medications you’re taking to avoid overlapping ingredients or potential harm.
- Inform your healthcare provider about any allergies or medical conditions you have to ensure safe use.
- If you experience any unusual symptoms or side effects, contact your healthcare provider immediately.
- Store medications properly in a cool, dry place, away from sunlight, children, and pets.
- Complete the full course of Amoxicillin as prescribed, even if you start feeling better.
- Avoid alcohol while taking any medication, including Tylenol, Advil, and Amoxicillin, as it can interact and cause adverse effects.
- Keep your healthcare provider informed about your progress and any concerns you may have during the treatment.
- Prioritize your health and safety by seeking professional advice and following the prescribed guidelines for medication use.
Just make sure you properly complete your Amoxicillin course for adequate eradication of the infection-causing bacteria in your body. Leaving antibiotic therapy halfway can lead to the worsening of infection.
If you are confused about taking the right kind of painkiller with your antibiotic, you can always ask your doctor or pharmacist.
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References
1.-
Gerriets V, Anderson J, Nappe TM. Acetaminophen. 2022 Sep 18. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 29493991. https://www.ncbi.nlm.nih.gov/books/NBK482369
2.-
Ngo VTH, Bajaj T. Ibuprofen. 2023 May 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 31194439. https://www.ncbi.nlm.nih.gov/books/NBK542299
3.-
Akhavan BJ, Khanna NR, Vijhani P. Amoxicillin. 2022 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 29489203. https://www.ncbi.nlm.nih.gov/books/NBK482250
