Can Mupirocin be used for yeast infections? 

Mupirocin is an antibiotic that does not work for the treatment of yeast infections.

Yeast infections can be treated with antifungal medications. 

Seek medical attention if you suspect yeast infections. Your doctor will assess the site of the infection and its severity and will prescribe the best medication for your condition.

Can Mupirocin be used for yeast infections? 

No, Mupirocin can not be used for yeast infections. 

Mupirocin is a topical antibiotic used for the management and treatment of bacterial infections (1,2).  

Yeast is a fungus, and it does not respond to antibacterials. 

Don’t take antibacterial medication for the treatment of fungal or viral infections. Different medications are required for each of these infections, and they only respond to specific treatments. 

What is the clinical indication of Mupirocin?

According to the package insert, Mupirocin is indicated for the topical treatment of impetigo caused by susceptible isolates of Staphylococcus aureus and Streptococcus pyogenes, specifically (2).

How to treat a yeast infection? 

Yeast infections are caused by fungus and they are treated with antifungal medications. There are different types of antifungal drugs available in various pharmaceutical forms (oral, topical, or vaginal). Some medications belonging to the class of antifungals are:

  • Nystatin
  • Clotrimazole
  • Amphotericin B
  • Miconazole
  • Econazole
  • Fluconazole

Depending on the location and severity of your infection, your doctor will guide you on the most suitable antifungal treatment (3).

How to know you have a yeast infection?

Following are some of the signs and symptoms of yeast infections (3,4):

Vaginal yeast infections:

  • Vaginal and vulvar itchiness and irritation
  • Odourless, thick, white discharge
  • Discomfort and burning during urination and sexual activity
  • Redness and swelling of the vulva
  • Discomfort or pain experienced during sexual activity

Non-vaginal yeast infections:

  • Redness and rash on the skin
  • Swelling and soreness of the affected area
  • Oral thrush (white patches in the mouth)
  • Painful or difficult swallowing
  • Itchy, flaky skin
  • Patches of shiny, white skin
  • Pain or discomfort in the affected area
  • Foul-smelling discharge in skin folds

Reach out to your healthcare provider if you have some of the above-mentioned signs and symptoms.

Yeast infections should be properly diagnosed and treated. Untreated infections can lead to disturbing complications. This is why proper treatment is essential.


In this concise article, we have discussed the potential effectiveness of Mupirocin in treating yeast infections. Furthermore, we have covered the clinical uses of Mupirocin and discussed the symptoms and treatments for yeast infections.

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Johns Hopkins Medicine. Conditions and Diseases. Yeast Infection [Internet] [cited 2023 Jul 25]. Available: