Can expired Zofran hurt you?

Can expired Zofran hurt you?

No, expired Zofran won’t necessarily ‘hurt’ you, but it will not help relieve your nausea and vomiting. This is because research studies have indicated that Zofran can start to slowly lose its potency once it’s past the expiration date. 

Now, this does not make the drug ‘toxic’ in any way, but it makes Zofran ineffective. No matter how much you take, you will not be able to achieve the therapeutic response you’re hoping for. This is why it’s best to stick with Zofran which is still in effect. 

However, people are different and they may respond to expired meds differently. This is why it’s best to not take medications that are expired. 

Why does the FDA recommend against the use of expired meds?

The Food and Drug Administration (FDA) has recommended avoiding using expired meds as there are not many research studies conducted on expired meds and they may contain potential health risks that we are not aware of (1).

Expired medications have no guarantee from the manufacturers regarding their safety and efficacy. Once a medication expires, there is no easy way to check its potency and overall safety. It may not cause any effect, either positive or negative.

However, some individuals are sensitive, especially people who have compromised liver functions or immunity. Such people are at high risk of getting negatively affected by expired medications. 

This is why it’s a general rule to safely discard expired medications and replace them with fully potent ones. 

Final words

Although expired Zofran may not harm your health, it still should not be taken. If you are struggling with symptoms that Zofran treats, it’s best to go and get new tablets. Taking expired medications could damage your health unpredictably, and it’s just not worth the risk. 

It is also important to note that proper use of medications is the key to achieving the best possible therapeutic response. So make sure you don’t pair Zofran with incompatible medication and excessive alcohol intake. If you have any queries, please reach out to your doctor.

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U.S. Food and Drug Administration. Don’t Be Tempted to Use Expired Medicines [Internet]. Silver Spring (MD): U.S. Food and Drug Administration; 2021 [cited 2022 Oct 19]. Available from: