Can Accutane cause feminine-area dryness? (3+ ways to prevent it))

In this article, we will discuss how Accutane leads to feminine-area dryness, research studies, preventive measures, and alternative acne treatments.

Can Accutane cause feminine-area dryness?

Yes, Accutane can lead to feminine-area dryness which is proven through many clinical studies. It is observed in almost half of the patients who are on Accutane (2)(3). However, every individual is different when body chemistry and genetic makeup are concerned. This can alter a person’s response to drugs.

What does research suggest?

Accutanes’s primary action is to reduce sebum production and regulate skin cell growth, but may also impact hormone levels, which can disrupt moisture balance and cause dryness in the private area (1).

While scientific research on the connection between Accutane and feminine-area dryness is limited, anecdotal reports and some studies suggest a possible association.

Findings from a survey conducted with 50 female patients indicate that 32% experienced feminine-area dryness, 22% reported valvular discomfort, 20% encountered pain during sexual intercourse, 10 % reported cuts and tears (fissures), and 24% had a new or heightened need for lubrication (2).

In an analytical cross-sectional study involving 10 participants, the most commonly occurring adverse effects were dyspareunia (reported by 40.0% of participants), feminine-area dryness (also reported by 40.0% of participants), and vulval burning (likewise reported by 40.0% of participants). These adverse effects were observed to co-occur in some cases (3).

How to prevent Accutane-induced feminine-area dryness?

Following are the ways to prevent feminine-area dryness associated with Accutane (4):

  • Drinking plenty of water helps to keep your body well hydrated, which in turn can aid in preserving mucous membrane moisture, including the private area.
  • Private-area moisturizers and lubricants provide much-needed relief from dryness and discomfort. These products can be applied regularly to enhance the internal moisture and reduce friction during sexual activity.
  • Be mindful of the products you use on your skin while on Accutane. Choose gentle and natural skin care products that are free from harsh chemicals and fragrances. This helps prevent further irritation and dryness in the private area.
  • Wearing breathable fabrics like cotton underwear allows for better air circulation in the genital area. This can help reduce moisture loss and prevent further dryness and discomfort.
  • Pelvic floor exercises, often referred to as Kegel exercises, can improve pelvic muscle tone and increase blood flow to the private area. This can be beneficial in maintaining the feminine-area’s health and reducing the severity of dryness.
  • In cases of severe or persistent private-area dryness while on Accutane, it is imperative to seek medical intervention promptly.

What are alternative treatments for Acne?

If a patient is intolerant to Accutane and is experiencing severe or persistent side effects, it’s better to switch to alternative treatments that include (5):

  • Topical preparations of antibiotics like Erythromycin, Clindamycin, and Mupirocin are effective in treating acne.
  • Dietary changes and the addition of probiotics can be helpful.
  • Herbal remedies like tea tree oil can help reduce acne.
  • Laser techniques and chemical peels may be beneficial.

Effectiveness varies, and it’s essential to consult a healthcare provider before trying these alternatives.

Final words:

Accutane, renowned for its acne-fighting powers, has a lesser-known side effect which is feminine-area dryness. While the link between Accutane and feminine-area dryness is supported by clinical studies, preventive measures such as hydration, moisturizers, and gentle skincare can alleviate discomfort. Exploring alternative acne treatments like topical antibiotics and herbal remedies essential for those facing Accutane intolerance. Remember, consulting a healthcare provider ensures informed choices on your journey to clear skin while prioritizing your well-being.

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References

1.-

Label: ACCUTANE- isotretinoin capsule, gelatin coated Dailymed (Internet) https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b524a51-a16b-496e-b764-11c98c479c36

2.-

Cunningham L, Menzies S, Moore E, Shudell E, Moloney FJ, Ralph N. Mucocutaneous adverse effects of the genital and perianal skin from isotretinoin therapy. Journal of the American Academy of Dermatology. 2020 Oct 1;83(4):1174-5. https://doi.org/10.1016/j.jaad.2020.10.078

3.-

Batista CCM, Lopes LRS, Lopes LPS, Lopes IMRS. Adverse effects in the female external genitalia of patients with acne vulgaris treated with isotretinoin. Research, Society and Development. 2022;11(5):e18811527533. https://rsdjournal.org/index.php/rsd/article/view/27533 Batista CCM, Lopes LRS, Lopes LPS, Lopes IMRS. Adverse effects in the female external genitalia of patients with acne vulgaris treated with isotretinoin. Research, Society and Development. 2022;11(5):e18811527533. https://rsdjournal.org/index.php/rsd/article/view/27533

4.-

Kunin A. The DERMAdoctor skinstruction manual: The smart guide to healthy, beautiful skin and looking good at any Age. Simon and Schuster; 2007 Nov 1. https://books.google.com.pk/books?id=yCyofv7MmGQC&lpg=PR13&ots=QKDuRZxkT6&dq=how%20to%20prevent%20Accutane-induced%20vaginal%20dryness&lr&pg=PA23#v=onepage&q=how%20to%20prevent%20Accutane-induced%20vaginal%20dryness&f=false 

5.-

Hauk L. Acne Vulgaris: Treatment Guidelines from the AAD. Am Fam Physician. 2017 Jun 1;95(11):740-741. PMID: 28671431. https://pubmed.ncbi.nlm.nih.gov/28671431/