What to do if you have missed the second shot of the Shingrix vaccine?
By
Dr Drielli Vital-Fujii (PhD)
Author bio
Dr Drielli Vital-Fujii, PhD, is a Pharmacist with expertise in Drug Design and Development, Enzymes, Molecular Modelling, and Photodynamic Therapy. She writes and reviews content on these topics.
Dr Drielli Vital-Fujii’s Highlights:
- Postdoctoral fellow at the Department of Biochemistry at the University of São Paulo, emphasizing therapy of neglected diseases using light.
- PhD in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Six months as an international researcher at the Center for Discovery and Innovation in Parasitic Diseases (University of California San Diego)
- Master’s degree in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Bachelor of Pharmacy at the University of Mogi das Cruzes – São Paulo / Brazil
Professional Experience:
2012 – 2018 Project manager at University of São Paulo – Pharmacy Department
Dr Drielli Vital-Fujii has worked with computational studies, synthesis, biological evaluation, design, and development of new inhibitor candidates for Chagas Disease and Leishmaniasis.
2017 – 2017 International research fellow at University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences – Center for Discovery and Innovation in Parasitic Diseases.
She used Virtual Screening (VS) and High-Throughput Screening (HTS) Integration in the Discovery of new drugs against neglected tropical diseases (NTDs).
2018 – 2019 Faculdades Oswaldo Cruz
Dr Drielli Vital-Fujii was a professor in the Faculty of Pharmacy, teaching the subjects of Pharmaceutical Chemistry and Drug Development.
2019 – 2021 Researcher in Biochemistry University of São Paulo – Biochemistry Department
She applied Photodynamic Therapy in Leishmaniasis Treatment, mentored undergraduate students in scientific activities, and wrote, executed, translated, and reported scientific projects with funding agencies.
2023-2023 UniPiaget – University Center.
Dr Drielli Vital-Fujii was a Biology, Nutrition, Physiotherapy, and Pharmacy professor.
Education:
2018 -2021 Postdoctoral at the Department of Biochemistry at the University of São Paulo
2013 -2018 PhD of Science: Drugs and Medicines at Department of Pharmacy at University of São Paulo
2012 -2013 M.Sc. of Sciences: Drugs and Medicines at the Department of Pharmacy at the University of São Paulo
2005-2008 Bachelor of Pharmacy at the University of Mogi das Cruzes
The leading publications of Dr Drielli Vital-Fujii are:
Vital-Fujii, D.G, Baptista, M.S. (2021). Progress in the photodynamic therapy treatment of Leishmaniasis. Brazilian Journal of Medical and Biological Research, 54, 1-11.
Gatti, F. M., Gomes, R.A., da Fonseca, A.L., Lima, E.J.C., Vital-Fujii, D.G., Taranto, A.G., Varotti, F.P., Trossini, G.H.G. (2020). Antiplasmodial activity of sulfonylhydrazones: in vitro and in silico approaches. Future medicinal chemistry, 13, 233-250.
Silva, E.J., Bezerra-Souza, A., Passero, L.F., Laurenti, M.D., Ferreira, G.M., Fujii, D.G.V., et al. (2018). Synthesis, leishmanicidal activity, structural descriptors and structure-activity relationship of quinoline derivatives. Future medicinal chemistry, 10, 2069-2085.
Leite, F.H.A., Froes, T.Q., da Silva, S.G., de Souza, E.I.M., Vital-Fuji,i D.G., Trossini, G.H.G., et al. (2017). An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors. European Journal of Medicinal Chemistry, 132, 322-332.
Vital, D.G., Damasceno, F.S., Rapado, L.N., Silber, A.M., Vilella, F.S., Ferreira, R.S., et al. (2017). Application of bioisosterism in design of the semicarbazone derivatives as cruzain inhibitors: a theoretical and experimental study. Journal of Biomolecular Structure and Dynamics, 35, 1244–1259.
Mello, J. F.R., Gomes, R.A., Vital-Fujii, D.G., Ferreira, G.M., Trossini, G.H.G. (2017). Fragment-based drug discovery as alternative strategy to the drug development for neglected diseases. Chemical Biology & Drug Design, 90, 1067-1078.
Pantaleao, S.Q., Fujii, D.G.V., Maltarollo, V.G., da C. Silva, D., Trossini, G.H.G., Weber, K.C., et al. (2017). The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery. Medicinal Chemistry, 13, 706-720.
Vital, D., Arribas, M., Trossini, G. (2014). Molecular Modeling and Docking Application to Evaluate Cruzain Inhibitory Activity by Chalcones and Hydrazides. Letters in Drug Design and Discovery, 11, 249-255.
Blau, L., Menegon, R.F., Trossini, G.H.G., Molino, J.V.D., Vital, D.G., Cicarelli, R.M.B., et al. (2013). Design, synthesis and biological evaluation of new aryl thiosemicarbazone as antichagasic candidates. European Journal of Medicinal Chemistry, 67, 142-151.
You can view some of Dr Drielli’s work below and links to her professional profile.
Orcid: https://orcid.org/0000-0001-9270-0466
Research Gate: https://www.researchgate.net/profile/Drielli-Gomes-Vital-Fujii
Scopus: https://www.scopus.com/authid/detail.uri?authorId=55829534000
Google Scholar: https://scholar.google.com/citations?user=F9U50AEAAAAJ&hl=pt-BR
Linkedin: linkedin.com/in/driellivital
Escavador: https://www.escavador.com/sobre/6101380/drielli-gomes-vital
CDIPD: https://cdipd.org/index.php/about-us/visiting-scientists
What to do if you have missed the second shot of the Shingrix vaccine?
If you have missed the second shot of the Shingrix vaccine, get it as soon as you can. The second Shingrix Shot is supposed to be taken 2-6 months after the first one (1,2).
Although it is best to follow your vaccination schedule vigilantly for maximum protection, if you have somehow missed it, it’s okay! You don’t have to start the whole thing again. You can just simply go for the second shot.
However, make sure you get the same one as the first and second shots of the Shingrix vaccine exactly the same, and there’s not even a minor difference whatsoever. So get your Shingrix shot as soon as you can if more than 6 months have passed since your first shot.
Important guidelines for the Shingrix vaccine
Some important guidelines for the Shingrix vaccine include (1,2):
- Shingrix is recommended for adults aged 50 years and older, regardless of whether they have had chickenpox or shingles before.
- The vaccine is administered as a two-dose series, with the second dose given 2 to 6 months after the first dose. It’s essential to complete the full series to get maximum protection.
- It’s crucial to prioritize getting the second dose within the recommended timeframe for optimal effectiveness.
- Even if you’ve had shingles in the past, it’s still essential to get vaccinated to reduce the risk of future shingles outbreaks. However, make sure you wait for the shingles symptoms to subside before vaccination.
- Shingrix can be given simultaneously with other vaccines, but if you receive different vaccines on the same day, like the influenza vaccine. However, they should be administered at different injection sites.
- Before getting the vaccine, inform your healthcare provider about any allergies or medical conditions you may have.
- After vaccination, some people may experience side effects like soreness at the injection site, fatigue, headache, or muscle pain. These usually subside within a few days.
- Although rare, if you experience severe allergic reactions or signs of anaphylaxis (difficulty breathing, swelling, etc.), seek immediate medical attention.
- Shingrix is not recommended for pregnant or breastfeeding women.
- If you miss the recommended interval for the second dose, try to get it as soon as possible without restarting the series.
Final words
To sum up, it’s important to get the second dose of your Shingix vaccine right on time for maximum protection. If you have missed the second shot, make sure to get it as soon as you can. If you are confused about getting a second shot, please talk to your doctor or pharmacist.
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References
1.-
Centers for Disease Control and Prevention, CDC. What Everyone Should Know about the Shingles Vaccine – Shingrix [Internet]. Available from: https://www.cdc.gov/shingles/vaccination.html
2.-
Centers for Disease Control and Prevention, CDC. Shingrix Recommendations [Internet]. Available from: https://www.cdc.gov/vaccines/vpd/shingles/hcp/shingrix/recommendations.html
