What happens if you take Ozempic twice a week?

In this article, we will discuss the potential risks of taking Ozempic, a medication used to manage diabetes and obesity, twice a week. We will also discuss the management of symptoms associated with Ozempic overdose and the best way and time for the administration of this drug.

What happens if you take Ozempic twice a week?

Taking Ozempic (Semaglutide) twice can lead to an overdose, as this medication should only be administered once weekly. Overdosing on Ozempic may cause disturbing symptoms, one of which is hypoglycemia – which is the most concerning symptom (1). 

If you suspect an overdose or experience any unusual symptoms, seek immediate medical attention.

What are the symptoms associated with Ozempic overdose?

Taking an overdose of Ozempic can lead to hypoglycemia, which is when the blood sugar level drops too low. Hypoglycemia can cause various symptoms that can vary from person to person (1). 

Common signs of low blood sugar include feeling shaky, dizzy, or lightheaded. You might also experience sweating, confusion, irritability, and a rapid heartbeat (2). Some people may feel extremely hungry or have sudden mood changes, feeling anxious or nervous.

In severe cases of hypoglycemia, individuals may become weak, have trouble concentrating, and may even lose consciousness or have seizures. It’s crucial to recognize these symptoms and take prompt action if you suspect low blood sugar levels.

If you experience symptoms of hypoglycemia after taking Ozempic, it is essential to treat it immediately. You can consume a fast-acting source of sugar, such as glucose tablets, fruit juice, or candies, to raise your blood sugar quickly.

However, it’s best to discuss this with your doctor prior to getting an Ozempic shot, and the proper ways of managing hypoglycemia in case it happens should also be discussed beforehand.

Ozempic overdose can also cause gastrointestinal side effects and other possible complications, that can vary from person to person (3,4). This is why overdosing on this medication should be managed right away.

What are the dosage recommendations for Ozempic?

The proper dosage recommendations for Ozempic are (1):

PurposeDosage Recommendation
Type 2 Diabetes0.25 mg injected under the skin once a week for 4 weeks. The dose may be increased by your doctor as needed, but usually not more than 1 mg once a week.
Weight Management0.25 mg injected under the skin once a week for 4 weeks. The dose may be increased by your doctor every 4 weeks, up to a maximum of 1 mg once a week.

*These dosage recommendations are for adults and children aged 12 years and older. For children younger than 12 years of age, the dose should be determined by a healthcare provider.

What to do if you have accidentally administered Ozempic twice in one week? 

If you have administered Ozempic twice in one week, it’s important to take immediate action and seek medical advice. Get in touch with your healthcare provider or doctor right away to explain the situation.

They will be there to offer you specific guidance on what you should do next. Sometimes, they might suggest closely monitoring your blood sugar levels to watch for any signs of hypoglycemia, which is when your blood sugar becomes too low.

Hypoglycemia can bring about symptoms such as shakiness, sweating, dizziness, confusion, and a rapid heartbeat. If you experience any of these signs or if you’re not sure what steps to take, don’t hesitate to contact your healthcare provider or seek medical help without delay. 

If you find your weekly dose of Ozempic insufficient or you fail to see a positive change in your blood sugar levels or your weight, please discuss your concerns with your doctor. Ozempic can take some time to work (1). Just don’t double up the dose or administer it more frequently on your own.

What to do if you have missed your weekly Ozempic dose?

If you have missed your weekly Ozempic dose, inform your healthcare provider. 

In the meantime, check your calendar or set a reminder to take the missed dose as soon as you remember. However, if your next scheduled dose is just around the corner, it’s better to wait and take the next dose on your regular day.

Remember, it’s crucial not to double up on the dose or take two doses close together to make up for the missed one. Doing so can lead to an overdose and increase the risk of side effects (1). Always follow the dosing schedule provided by your healthcare provider.


In this article, we have discussed the consequences of taking Ozempic twice in one week. We have also discussed dosage recommendations for the medication and what one should do in case of overdosing or missing a dose.

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The Food and Drug Administration (FDA). HIGHLIGHTS OF PRESCRIBING INFORMATION. OZEMPIC (semaglutide) injection, for subcutaneous use. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/209637lbl.pdf


Mathew P, Thoppil D. Hypoglycemia. 2022 Dec 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 30521262. Available from: https://www.ncbi.nlm.nih.gov/books/NBK534841


Shu Y, He X, Wu P, Liu Y, Ding Y, Zhang Q. Gastrointestinal adverse events associated with semaglutide: A pharmacovigilance study based on FDA adverse event reporting system. Front Public Health. 2022 Oct 20;10:996179. doi: 10.3389/fpubh.2022.996179. PMID: 36339230; PMCID: PMC9631444. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631444/


Smits MM, Van Raalte DH. Safety of Semaglutide. Front Endocrinol (Lausanne). 2021 Jul 7;12:645563. doi: 10.3389/fendo.2021.645563. Erratum in: Front Endocrinol (Lausanne). 2021 Nov 10;12:786732. PMID: 34305810; PMCID: PMC8294388. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294388/