Is yellow discharge after Monistat 1 normal?
By
Dr Drielli Vital-Fujii (PhD)
Author bio
Dr Drielli Vital-Fujii, PhD, is a Pharmacist with expertise in Drug Design and Development, Enzymes, Molecular Modelling, and Photodynamic Therapy. She writes and reviews content on these topics.
Dr Drielli Vital-Fujii’s Highlights:
- Postdoctoral fellow at the Department of Biochemistry at the University of São Paulo, emphasizing therapy of neglected diseases using light.
- PhD in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Six months as an international researcher at the Center for Discovery and Innovation in Parasitic Diseases (University of California San Diego)
- Master’s degree in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Bachelor of Pharmacy at the University of Mogi das Cruzes – São Paulo / Brazil
Professional Experience:
2012 – 2018 Project manager at University of São Paulo – Pharmacy Department
Dr Drielli Vital-Fujii has worked with computational studies, synthesis, biological evaluation, design, and development of new inhibitor candidates for Chagas Disease and Leishmaniasis.
2017 – 2017 International research fellow at University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences – Center for Discovery and Innovation in Parasitic Diseases.
She used Virtual Screening (VS) and High-Throughput Screening (HTS) Integration in the Discovery of new drugs against neglected tropical diseases (NTDs).
2018 – 2019 Faculdades Oswaldo Cruz
Dr Drielli Vital-Fujii was a professor in the Faculty of Pharmacy, teaching the subjects of Pharmaceutical Chemistry and Drug Development.
2019 – 2021 Researcher in Biochemistry University of São Paulo – Biochemistry Department
She applied Photodynamic Therapy in Leishmaniasis Treatment, mentored undergraduate students in scientific activities, and wrote, executed, translated, and reported scientific projects with funding agencies.
2023-2023 UniPiaget – University Center.
Dr Drielli Vital-Fujii was a Biology, Nutrition, Physiotherapy, and Pharmacy professor.
Education:
2018 -2021 Postdoctoral at the Department of Biochemistry at the University of São Paulo
2013 -2018 PhD of Science: Drugs and Medicines at Department of Pharmacy at University of São Paulo
2012 -2013 M.Sc. of Sciences: Drugs and Medicines at the Department of Pharmacy at the University of São Paulo
2005-2008 Bachelor of Pharmacy at the University of Mogi das Cruzes
The leading publications of Dr Drielli Vital-Fujii are:
Vital-Fujii, D.G, Baptista, M.S. (2021). Progress in the photodynamic therapy treatment of Leishmaniasis. Brazilian Journal of Medical and Biological Research, 54, 1-11.
Gatti, F. M., Gomes, R.A., da Fonseca, A.L., Lima, E.J.C., Vital-Fujii, D.G., Taranto, A.G., Varotti, F.P., Trossini, G.H.G. (2020). Antiplasmodial activity of sulfonylhydrazones: in vitro and in silico approaches. Future medicinal chemistry, 13, 233-250.
Silva, E.J., Bezerra-Souza, A., Passero, L.F., Laurenti, M.D., Ferreira, G.M., Fujii, D.G.V., et al. (2018). Synthesis, leishmanicidal activity, structural descriptors and structure-activity relationship of quinoline derivatives. Future medicinal chemistry, 10, 2069-2085.
Leite, F.H.A., Froes, T.Q., da Silva, S.G., de Souza, E.I.M., Vital-Fuji,i D.G., Trossini, G.H.G., et al. (2017). An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors. European Journal of Medicinal Chemistry, 132, 322-332.
Vital, D.G., Damasceno, F.S., Rapado, L.N., Silber, A.M., Vilella, F.S., Ferreira, R.S., et al. (2017). Application of bioisosterism in design of the semicarbazone derivatives as cruzain inhibitors: a theoretical and experimental study. Journal of Biomolecular Structure and Dynamics, 35, 1244–1259.
Mello, J. F.R., Gomes, R.A., Vital-Fujii, D.G., Ferreira, G.M., Trossini, G.H.G. (2017). Fragment-based drug discovery as alternative strategy to the drug development for neglected diseases. Chemical Biology & Drug Design, 90, 1067-1078.
Pantaleao, S.Q., Fujii, D.G.V., Maltarollo, V.G., da C. Silva, D., Trossini, G.H.G., Weber, K.C., et al. (2017). The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery. Medicinal Chemistry, 13, 706-720.
Vital, D., Arribas, M., Trossini, G. (2014). Molecular Modeling and Docking Application to Evaluate Cruzain Inhibitory Activity by Chalcones and Hydrazides. Letters in Drug Design and Discovery, 11, 249-255.
Blau, L., Menegon, R.F., Trossini, G.H.G., Molino, J.V.D., Vital, D.G., Cicarelli, R.M.B., et al. (2013). Design, synthesis and biological evaluation of new aryl thiosemicarbazone as antichagasic candidates. European Journal of Medicinal Chemistry, 67, 142-151.
You can view some of Dr Drielli’s work below and links to her professional profile.
Orcid: https://orcid.org/0000-0001-9270-0466
Research Gate: https://www.researchgate.net/profile/Drielli-Gomes-Vital-Fujii
Scopus: https://www.scopus.com/authid/detail.uri?authorId=55829534000
Google Scholar: https://scholar.google.com/citations?user=F9U50AEAAAAJ&hl=pt-BR
Linkedin: linkedin.com/in/driellivital
Escavador: https://www.escavador.com/sobre/6101380/drielli-gomes-vital
CDIPD: https://cdipd.org/index.php/about-us/visiting-scientists
Is yellow discharge after Monistat 1 normal?
While or pale yellow discharge after Monistat is considered normal. However, a few factors should be considered:
- The smell of the discharge
- If it’s irritating your vagina or the skin around it
- The frequency of discharge
Monistat is used for the management and treatment of vaginal yeast infections and it is supposed to stay in your vagina for a week (1,2). The discharge could normally be due to the ongoing yeast infection and it should go away on its own.
However, if the discharge is causing irritation or it has a foul smell, you should definitely get it tested. Fungal infections can make your vagina more susceptible to other infections like bacterial vaginosis, by disturbing its pH and your vaginal immunity (3,4).
The yellow smelly discharge could also be a sign of such a comorbid infection. Make sure you get it screened if it’s symptomatic. Asymptomatic discharge is nothing to worry about.
Differences between normal Vs abnormal yellow vaginal discharge after using Monsitat 1
After taking Monistat 1, it’s common to experience some changes in vaginal discharge. Here’s a comparison between normal and abnormal yellow vaginal discharge: (1)
Normal Yellow Vaginal Discharge:
- Colour: Normal vaginal discharge can vary in colour, and a light yellow hue is generally considered normal.
- Consistency: Normal discharge is usually clear or slightly cloudy and has a sticky or slippery texture.
- Odour: Normal discharge may have a mild, slightly musky odour or no significant odour at all.
- Other Symptoms: Normal discharge is typically not accompanied by any itching, burning, or discomfort in the vaginal area.
Abnormal Yellow Vaginal Discharge:
- Intense Yellow Color: If the discharge is a strong, bright, or dark yellow colour, it may indicate an underlying issue and should be evaluated further.
- Unusual Consistency: Abnormal discharge may have a thick, clumpy, or cottage cheese-like consistency, which can indicate a yeast infection or other vaginal infection.
- Unpleasant Odor: Abnormal discharge may have a strong, foul odour, particularly if it is accompanied by itching, burning, or irritation. This could be a sign of a bacterial infection or other vaginal condition.
- Other Symptoms: Abnormal discharge is often accompanied by other symptoms such as itching, redness, swelling, pain during urination or intercourse, or general discomfort in the vaginal area.
What to do if you are concerned about yellow vaginal discharge after using Monsitat 1?
If you have concerns about yellow vaginal discharge after using Monistat 1, it’s important to reach out to your healthcare provider. They can evaluate your symptoms, listen to your concerns, and provide appropriate recommendations.
They may ask you questions about your condition, perform necessary tests if required, and recommend appropriate treatment options or further steps to address your concerns – as there could be other factors contributing to the yellow colouration of your vaginal discharge.
Remember, your healthcare provider is the best resource to help you understand and manage any concerns related to your vaginal health.
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References
1.-
Sawyer PR, Brogden RN, Pinder RM, Speight TM, Avery GS. Miconazole: a review of its antifungal activity and therapeutic efficacy. Drugs. 1975;9(6):406-23. doi: 10.2165/00003495-197509060-00002. PMID: 1149649. https://pubmed.ncbi.nlm.nih.gov/1149649/
2.-
Upmalis DH, Cone FL, Lamia CA, Reisman H, Rodriguez-Gomez G, Gilderman L, Bradley L. Single-dose miconazole nitrate vaginal ovule in the treatment of vulvovaginal candidiasis: two single-blind, controlled studies versus miconazole nitrate 100 mg cream for 7 days. J Womens Health Gend Based Med. 2000 May;9(4):421-9. doi: 10.1089/15246090050020745. PMID: 10868615. https://pubmed.ncbi.nlm.nih.gov/10868615/
3.-
Jeanmonod R, Jeanmonod D. Vaginal Candidiasis. 2022 Jul 18. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 29083806. https://www.ncbi.nlm.nih.gov/books/NBK459317
4.-
Vaginal yeast infection (thrush): Overview. Germany: Institute for Quality and Efficiency in Health Care (IQWiG); Bookshelf ID: NBK543220. https://www.ncbi.nlm.nih.gov/books/NBK543220/
