Does sertraline come in 150 mg tablet? (3 differences)

This article will answer the question: ‘Is Sertraline available in 150 mg tablet form?’ Furthermore, we will delve into the various available dosage forms, highlighting their distinctions.

Does Sertraline come in 150 mg tablet?

Sertraline is not available in 150 mg tablet form. Instead, 150 mg of sertraline is available in capsule form.

The tablet form of sertraline comes in strengths of 25 mg, 50 mg, and 100 mg, while the 150 and 200 mg strengths are found in capsules. (1)

What is the difference between Sertraline tablets and capsules?

Sertraline is a widely prescribed medication used to manage various mental health conditions. It is available in two primary forms: tablets and capsules. While both forms serve the same therapeutic purpose, they differ in dosage forms. (1)

Tablets are solid forms of the medication, containing drugs and excipients. Capsules encase the medication in a shell, which dissolves in the digestive tract to release the drug.

Sertraline tablets come in several strengths, such as 25 mg, 50 mg, and 100 mg. Capsules are typically available in higher strengths, like 150 and 200 mg. (1,2)

Sertraline tablets are often designed to be split or crushed if necessary. Sertraline capsules should not be crushed or split, as it may compromise their effectiveness.

Both forms are administered orally and act in a similar manner within the body. The choice between tablets and capsules is influenced by dosage requirements.

Is 150 mg Sertraline too high?

The initial dosage of sertraline is a crucial decision in the treatment process, and it’s common for individuals to wonder if 150 mg is too high, to begin with. 

Starting with a 150 mg dose of sertraline is generally considered high and is not the typical approach. Healthcare providers often initiate treatment with lower doses to gauge an individual’s response and minimise the risk of potential side effects.

Usually, Sertraline is titrated and the treatment is started with lower strengths, such as 25 mg or 50 mg. These lower doses serve as a starting point, allowing healthcare providers to assess how the medication affects the patient and whether adjustments are needed. 

Over time, if necessary, the dose can be gradually increased, with a maximum recommended dose of 200 mg per day. This incremental approach helps tailor the treatment to the individual’s needs and ensures safety.

Healthcare providers often prescribe 25 mg or 50 mg tablets for starting doses. If your condition requires a higher dosage, such as 150 mg, they may transition you to sertraline capsules. Your healthcare provider carefully manages this shift to ensure a seamless transition. (3)

Some conditions that commonly need a 150 mg maintained dose include Major Depressive Disorder (MDD), Panic Disorder (PD), and Obsessive-Compulsive Disorder (OCD). These conditions may require higher doses to manage symptoms effectively. (2)

It’s important to understand that sertraline, like many antidepressants, may take time for your body to adjust to and for therapeutic effects to become noticeable. Patience is critical during this process.

What are the side effects of the 150 mg Sertraline dose?

Here’s a list of some crucial side effects to look out for if you suspect 150 mg sertraline dose is high: (1,2)

  • Severe Nausea
  • Persistent Sweating
  • Extreme Irritability
  • Agitation
  • Dizziness
  • Sensory Disturbances (like paresthesia)
  • Confusion
  • Headache
  • Stomach upset

These side effects can be indicators that your dosage may be too high, and it’s essential to promptly consult your healthcare provider if you experience any of these symptoms. They can assess your condition and make any necessary adjustments to your medication regimen.

Is it possible to switch from Sertraline capsules to tablets?

Indeed, it is possible to switch from sertraline capsules to tablets under the guidance of your healthcare provider. Your doctor will prescribe the tablets as part of a tapering plan or if you’re transitioning from 150 mg capsules to a lower dose.

It is always advised to not abruptly stop taking Sertraline. Gradually reducing the dose is important to avoid withdrawal effects. Since the lowest dose available in capsules is 150 mg, a gradual reduction of sertraline may necessitate using 100 mg, 50 mg, or 25 mg tablets.

Your healthcare provider will carefully tailor this transition to ensure your treatment remains effective and well-managed. Always consult your healthcare provider before making any changes to your medication regimen.


In conclusion, Sertraline is not available in 150 mg tablet form. Instead, 150 mg of sertraline is found in capsule form. Sertraline tablets are offered in strengths of 25 mg, 50 mg, and 100 mg, while the 150 and 200 mg strengths are available in capsules. Always consult a healthcare professional for accurate and safe medication management tailored to your needs.

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