Does Lyrica affect blood pressure? 

Does Lyrica affect blood pressure? 

Lyrica does not usually affect blood pressure as nothing major was observed during research studies. However, Lyrica may lower blood pressure in long-term users of this drug. 

The difference, however, is still not too much to be concerned about and it does depend on your dose and the frequency of dose administration. Some people are generally sensitive to medications and they may react differently, as compared to other individuals. 

Some experts also believe that an underlying condition may also alter the effects of Lyrica in some individuals. Make sure you talk to your healthcare provider if you think Lyrica is affecting your blood pressure. 

Only your doctor can determine if it’s safe for you to continue using Lyrica or if some dose adjustment will simply fix the problem. 

What factors can affect blood pressure while taking Lyrica?

When taking Lyrica, certain factors can influence how it affects your blood pressure. Here are some key points to understand (1,2):

Individual response

Each person’s body may react differently to Lyrica. Some individuals may experience changes in blood pressure, while others may not notice any significant effects. Factors such as your overall health, genetics, and individual sensitivity to medications can contribute to these variations.


The dosage of Lyrica prescribed by your healthcare provider can impact its effect on blood pressure. Higher doses of Lyrica may have a greater potential to cause changes in blood pressure compared to lower doses. Your healthcare provider will determine the appropriate dosage based on your specific condition and needs.

Duration of use

The duration of time you have been taking Lyrica can also play a role. Initially starting Lyrica or increasing the dosage may have a more noticeable impact on blood pressure compared to long-term use. However, individual responses may still vary.

Other medications

The combination of Lyrica with other medications you may be taking can influence blood pressure. Certain medications, such as those used for high blood pressure or cardiovascular conditions, can interact with Lyrica and affect blood pressure levels (3,4). 

It’s important to inform your healthcare provider about all the medications you are taking to ensure they are aware of any potential interactions.

Underlying health conditions

Pre-existing medical conditions, such as hypertension (high blood pressure) or cardiovascular problems, can interact with Lyrica and influence blood pressure (3,4). 

It’s important to discuss your medical history with your healthcare provider, as they can consider these factors when prescribing Lyrica and monitoring your blood pressure.

What to do if your blood pressure fluctuates while taking Lyrica?

If you notice that your blood pressure is fluctuating while taking Lyrica, it’s important to take the following steps:

Monitor your blood pressure and keep a record

Regularly check your blood pressure at home using a reliable blood pressure monitor. This will help you keep track of any changes or fluctuations. Make sure to follow the instructions provided with your blood pressure monitor for accurate readings.

It is also important to maintain a record of your blood pressure readings, noting the date, time, and values. This will provide useful information for your healthcare provider when assessing your condition and determining the best course of action.

Inform your healthcare provider

Reach out to your healthcare provider as soon as possible to inform them about your blood pressure fluctuations while taking Lyrica. They will be able to evaluate your situation and provide appropriate guidance.

Follow medical advice

Your healthcare provider may recommend adjustments to your Lyrica dosage or prescribe additional medications to help manage your blood pressure. It’s important to follow their instructions carefully and discuss any concerns or questions you may have.

Maintain a healthy lifestyle

Adopting a healthy lifestyle can support overall blood pressure management. This includes eating a balanced diet, engaging in regular physical activity, managing stress, limiting alcohol intake, avoiding tobacco products, and maintaining a healthy weight. 

These lifestyle factors can have a positive impact on blood pressure regulation.

Proper follow-ups

Attend scheduled follow-up appointments with your healthcare provider. They will monitor your blood pressure and assess your response to the medication. This allows them to make any necessary adjustments to your treatment plan.

Remember, it is crucial to discuss side effects with your doctor for achieving the desired therapeutic outcome without damaging your basic physiological functions. 

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