Does Lexapro interact with Tums? (Risks vs benefits)

This article will explore the potential interaction between Lexapro and Tums. It will discuss the separate mechanisms of action of Lexapro and Tums and their intended uses. 

Additionally, the article will demonstrate the benefits of taking these medications together and will cover the side effects that may occur as a result of their concurrent use. It will also mention the factors that can increase the risk of experiencing these side effects. 

Finally, the article will discuss how to safely take Tums with Lexapro, including important tips and recommendations.

Does Lexapro interact with Tums?

No, Lexapro doesn’t interact with Tums. Lexapro is an antidepressant, working as a selective serotonin reuptake inhibitor (SSRI). It is used for treating depression, anxiety disorders, and other related conditions. On the other hand, Tums is an over-the-counter antacid that contains calcium carbonate, which helps neutralise stomach acid and provides relief from heartburn and indigestion [1,2].

Given their separate mechanisms of action and different intended uses, there is no possibility for Lexapro and Tums to interact or impact each other’s effectiveness. However, even if there are no known chemical interactions between the two, it is always recommended to consult with a doctor before taking any over-the-counter medications like Tums while being treated with Lexapro.

What are the benefits of taking Lexapro and Tums together?

Taking Tums with Lexapro can potentially benefit the treatment in several ways. For instance, if someone suffers from heartburn, acid reflux, or gastrointestinal discomfort as a side effect of Lexapro, using Tums may help manage the associated discomfort, which can help the patient tolerate the treatment better [1].

Furthermore, by reducing these gastrointestinal side effects, Tums can contribute to improved adherence to Lexapro treatment. To illustrate, when patients experience fewer adverse effects, including heartburn and stomach aches, they are more likely to continue taking the medication as prescribed. Consequently, this can enhance and maximise the effectiveness of the treatment with Lexapro.

Additionally, since the patient’s gastrointestinal side effects, like Lexapro-induced acid reflux, are effectively managed with Tums, the doctor may not need to decrease the Lexapro dose, as that wouldn’t be necessary anymore. This ensures that the efficacy of Lexapro treatment is not compromised by a dose reduction.

What are the side effects of taking Tums with Lexapro?

While it is generally safe to take Lexapro and Tums together, certain individuals, such as those with underlying health conditions or increased medication sensitivity, may experience increased side effects when using them concurrently.

For instance, Lexapro can commonly cause symptoms like headaches, loss of appetite, nausea, dry mouth, and muscle twitching. Similarly, Tums can also result in these side effects, although this occurrence is less common [1,2].

What factors may increase side effects when combining Lexapro and Tums?

Certain risk factors can make people more susceptible to experiencing the side effects mentioned above when taking a combination of Lexapro and Tums. Some of these risk factors are mentioned below:

  • Taking high doses of Lexapro or Tums, or taking them for a very long period of time, can increase the likelihood of side effects.
  • Jumping to high doses of Lexapro without applying proper dose escalation under medical supervision while simultaneously taking Tums, can increase side effects.
  • Liver or kidney diseases can impair the body’s ability to metabolise and excrete Lexapro, leading to an increased risk of side effects, especially while taking Tums.
  • Concurrent use of other medications with similar side effects, alongside Lexapro and Tums, can increase the frequency and severity of their side effects.
  • The concurrent use of certain drugs can inhibit the liver enzymes that metabolise Lexapro, potentially resulting in an increased concentration, potency, and occurrence of side effects. Specifically, if Tums is also being administered, side effects such as headache, dry mouth, loss of appetite, and nausea may increase.
  • Older patients or patients with slow metabolisms may process medications at a slower rate, leading to higher drug concentrations in the body and more side effects.

How to safely take Tums with Lexapro?

Before considering the simultaneous use of Tums and Lexapro, it is recommended to consult your doctor. They can evaluate your specific health conditions and provide advice accordingly.

You should follow the prescribed dosage and directions for both drugs.

Your doctor may suggest taking Tums two hours before or after Lexapro to minimise any effects of absorption. To illustrate, Tums is a calcium supplement, and it is known that high calcium levels may interfere with the absorption of certain medications. Thus, it is recommended to separate their dosages to ensure the maximum efficacy of Lexapro.

Furthermore, you must inform your doctor about any unusual effects when using Tums and Lexapro concurrently, especially symptoms like headaches, muscle twitching, nausea, and dry mouth.

 

In conclusion, according to my knowledge, Lexapro does not interact with Tums, as they have separate mechanisms of action and different intended uses. In my perspective, taking Tums with Lexapro can potentially benefit the treatment by managing lexapro-induced heartburn or gastrointestinal discomfort. 

I believe this can help patients tolerate the treatment better and improve adherence to Lexapro. Additionally, this may eliminate the need for a dose reduction, ensuring the efficacy of Lexapro treatment.

In my opinion, factors such as high doses of medication, liver or kidney diseases, concurrent use of other medications with similar side effects, and slower metabolism can increase the likelihood of side effects from both drugs.

I recommend consulting a doctor, following the prescribed dosage and directions for both medications, and discussing any concerns about taking them together with a healthcare professional.

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References

1.-

andy K, Rosani A, Estevez R. Escitalopram. [Updated 2023 Nov 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557734/

2.-

Salisbury BH, Terrell JM. Antacids. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK526049/

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