Does Flexeril make you bloated? 

Does Flexeril make you bloated? 

Flexeril (Cyclobenzaprine) can make you bloated. This muscle relaxer is associated with some gastrointestinal side effects and it may make you gassy and bloated. 

This side effect is usually nothing to be concerned about and it does go away on its own with time, however, people with gastrointestinal problems may not do so well with Flexeril. 

In some cases, your doctor may prescribe you an NSAID along with Flexeril to help with pain associated with your muscle spasms. (1,2)

This combination surely works well for pain management but could be heavy on your stomach as NSAIDs also cause a number of gastrointestinal side effects. 

What is the incidence of bloating caused by Flexeril? 

The incidence of bloating caused specifically by Flexeril may vary from person to person. Some people may also gain weight on this medication. The exact frequency or percentage of individuals experiencing bloating as a side effect of Flexeril is not readily available.

It is important to note that bloating is considered a less common side effect of Flexeril, meaning that it occurs in a relatively small number of people who take the medication.

However, it’s important to consult with your healthcare provider or pharmacist for more specific information about the potential incidence of bloating associated with Flexeril and to discuss any concerns or symptoms you may be experiencing. 

What to do if Flexeril makes you bloated? 

Try taking Flexeril in between meals if it makes you bloated. Meds that can cause gastrointestinal side effects should always be taken with food to mitigate the severity of stomach damage. 

However, it’s always best to discuss such side effects with your healthcare provider. Flexeril may not suit everyone, as there are a lot of people who don’t do well on this muscle relaxant. 

If you personally feel that Flexeril makes your stomach heavy and makes you feel sick overall, talk to your doctor. There are other muscle relaxants that can easily replace Flexeril. 

As far as bloating is concerned, the common reason why that happens is trapped gases in your stomach that put pressure and cause your belly to expand. Flexeril may also cause weight loss in some rare cases.

Non-pharmacological ways to manage bloating 

Some non-pharmacological ways to manage bloating include:

  • Drink plenty of water. Staying hydrated can support digestion and help prevent water retention, which can contribute to bloating. 
  • Take your time to eat and thoroughly chew your food. It aids in the digestion process, reducing the likelihood of swallowing excess air that can lead to bloating.
  • Avoid carbonated drinks and fizzy beverages, as they contain gas bubbles that can contribute to bloating.
  • Limit gas-producing foods. Common culprits include beans, lentils, broccoli, cabbage, onions, and carbonated drinks. 
  • Manage stress, as stress can affect digestion and contribute to bloating.
  • Engage in regular physical activity. It can promote healthy digestion and help alleviate bloating. Incorporate exercises like walking, jogging, or yoga into your routine.

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Khan I, Kahwaji CI. Cyclobenzaprine. 2022 Sep 2. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 30020734.


Kobayashi H, Hasegawa Y, Ono H. Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol. 1996 Sep 5;311(1):29-35. doi: 10.1016/0014-2999(96)00402-5. PMID: 8884233.