Does Celexa interact with Hydrocodone? (3+ effects)
By
Ivan Kahwa
Author bio
Mr Ivan Kahwa is a chemist and phytopharmaceutical scientist with expertise in chemistry, pharmacology, phytochemistry, and Nanobiotechnology. He writes and reviews content on these topics.
Mr Ivan Kahwa’s Highlights:
Guest Researcher at the University of Leipzig, Senior Research Fellow/Scientist, and Lecturer at the Department of Pharmacy, Faculty of Medicine, Mbarara University of Science and Technology.
Professional Experience:
Mr Ivan joined PHARMBIOTRAC as a research fellow/scientist during his master of science tenure. He contributed to the development of most of the phytopharmaceutical products in the project. Furthermore, he participated in carrying out the pharmacological activities of the developed products in laboratory animals such as mice and rats in order to develop proper doses hence leading to pre-clinical studies.
With the above relevant research experience, Ivan started to work with the University of Leipzig on collaborative projects with Mbarara University to develop the chemistry of Ugandan Medicinal plants and their pharmacological activities. This was coupled with several consultative positions by different German NGOs. Mr. Kahwa is also a supporting in the teaching and learning at the Departments of Pharmacy and Pharmaceutical Sciences, Faculty of Medicine, Mbarara University of Science and Technology.
With the increase in antimicrobial resistance globally, Ivan retooled his thinking towards developing new naturally derived antibiotic regimens from Ugandan propolis with the assistance of nanotechnology to improve their delivery to microbial cells. Kahwa has also published over 28 articles in peer-reviewed journals and he is currently reviewing for many journals.
Education:
2023-2027: PhD in Pharmaceutical Sciences (ongoing) with a focus on Pharmaceutical Microbiology and Nanobiology at Mbarara University of Science and Technology.
2022: 2Msc. in Pharmacognosy and Natural Medicine Science at Mbarara University of Science and Technology.
2018: Bachelor of Science (Chemistry) at Mbarara University of Science and Technology.
Publications:
▪ Iqbal, S., Jabeen, F., Kahwa, I., & Omara, T. 2023. Suberosin Alleviates Thiazolidinedione-Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4-LPCAT3 and PI3K-AKT Signaling Pathways. Cardiovascular Toxicology. https://doi.org/10.1007/s12012-023-09804-7
▪ Gupta, A. K., Yadav, R., Sharma, S., Sawale, J., & Kahwa, I. 2023. Anti-ageing Activity and Antioxidant Activity of Methanol Extracts of Leaves and Flowers of Salvia officinalis and Rosmarinus officinalis. Journal of Young Pharmacists, 15(3), 448–455. https://doi.org/10.5530/jyp.2023.15.60
▪ Tolo, C.U., Kahwa, I., Nuwagira, U., Weisheit, A. and Ikiriza, H., 2023. Medicinal plants used in treatment of various diseases in the Rwenzori Region, Western Uganda. Ethnobotany Research and Applications, 25, pp.1-16.
https://ethnobotanyjournal.org/index.php/era/article/view/4683
▪ Kahwa, I., Ajayi, C.O., Yadav, R., Chauhan, N.S., Shah, K., Abdelgadir, A.A., Shegena, E.A., Daniel, S., Omara, T., Asiimwe, J.B. and Ikiriza, H., 2023. Pharmacognostic and phytochemical studies as an invaluable approach for correct identification of medicinal plants: The case of Artemisia vulgaris L. substituted for Artemisia annua L. in Western Uganda. TMR Integr Med, 7, p.e23004.
https://doi.org/10.53388/TMRIM202307004
▪ Nalimu, F., Oloro, J., Kahwa, I. and Ogwang, P.E., 2021. Review on the phytochemistry and toxicological profiles of Aloe vera and Aloe ferox. Future Journal of Pharmaceutical Sciences, 7, pp.1-21.
https://doi.org/10.1186/s43094-021-00296-2
▪ Elamin, O.H.S., Ali, M.A., Elgezuli, I.A.A., Bashir, M.A. and Kahwa, I., 2021. Diagnosis of pre-and post-treatment of echinococcus granulosus with counter current immune electrophoresis and bacterial co-agglutination. Journal of Microbiology and Infectious Diseases, 11(02), pp.88-94.
https://doi.org/10.5799/jmid.951600
Published book Chapter
▪ Kahwa, I., Ayesiga, I., Nakalema, S., Alinaiswe, R., Mbabazi, R. and Iqbal, S., 2023. Natural products in the management of onchocerciasis. In Natural Products in Vector-Borne Disease Management (pp. 63-80). Academic Press. Book Chapter.
https://doi.org/10.1016/B978-0-323-91942-5.00012-4
Submitted manuscripts Under Review:
▪ Comparison of the Wound Healing Activity of the Leaf and Leaf Ash Extracts of Vernonia amygdalina in Rats. Journal name: Clinical Phytoscience
▪ Ethnobotanical Survey of Medicinal plants used in the management of cancer in Uganda. Journal name: Journal of Herbal Medicine
▪ Ethnobotanical survey and phytochemical screening of medicinal plants used in treatment of epilepsy by PROMETRA-Uganda Traditional Health Practitioners in Mpigi District, Uganda. Journal name: Journal of Ethnopharmacology
Submitted book chapters under review
1.Book title: Algae as a Natural Solution for Water-Food-Energy Nexus, Section 4: Microalgae and cyanobacteria for food applications, Chapter 4.6: Safety, toxicological and allergenic aspects of using algae for food. Authors: Christine Kyarimpa, Tom Omute, Caroline K. Nakiguli, Alice V. Khanakwa4, Christopher Angiro, Ivan Kahwa, Fortunate Ahumuza, Timothy Omara*. Publisher: Springer Nature Singapore Pte Ltd. 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore.
2.Book title: Nutraceuticals Inspiring the Contemporary Therapy for Lifestyle Diseases. Chapter: Nutraceutical applications of Seaweeds and their Phytocompounds in Nutrition and Treatment of Diseases. Authors: Ivan Kahwa, Timothy Omara , Innocent Ayesiga , Gael Noel Neh Neba Ambe , Zehbanaz Javidbhai Panwala , Rachel Mbabazi , Shabnoor Iqbal , Christine Kyarimpa , Christine Betty Nagawa , Kamal Shah ,Nagendra Singh Chauhan* Publisher: CRC Press
You can view my works on the following professional sites:
Research Gate: https://www.researchgate.net/profile/Ivan-Kahwa
Google Scholar: https://scholar.google.com/citations?user=tOwrvqoAAAAJ&hl=en
ORCID: https://orcid.org/0000-0002-6440-3437
Linkedin: https://de.linkedin.com/in/ivan-kahwa-865450159
In this article, we will discuss the interactions between Celexa and Hydrocodone. We will also discuss what side effects one may experience by combining these two medications and how to manage the side effects associated with this interaction.
Does Celexa interact with Hydrocodone?
Yes, Celexa does interact with Hydrocodone. Both Celexa and hydrocodone are prescription medications used to treat different health conditions.
Their interaction may cause a life-threatening condition known as serotonin syndrome. Serotonin syndrome is caused when the level of serotonin rises to a toxic level in the brain.
Hydrocodone is a prescription medication used to relieve moderate to severe pain. It belongs to a class of drugs known as opioid analgesics or narcotics. It works by binding to opioid receptors in the brain and spinal cord which helps to decrease the perception of pain (1).
Celexa, on the other hand, is a selective serotonin reuptake inhibitor used to treat mental health conditions such as depression and anxiety (2).
If your treatment plan involves both of these medications, it is important to maintain open communication with your healthcare provider. You should closely monitor your response to this medication combination and report any concerning symptoms to ensure your treatment remains safe and effective.
What are the potential interactions between Celexa and Hydrocodone?
Celexa and Hydrocodone are generally not prescribed together for a combined therapeutic effect but may be used concurrently to address separate issues based on the patient’s specific medical condition and needs (3).
The potential interactions between Celexa and Hydrocodone can vary from person to person. It may include:
Increased risk of serotonin syndrome
One of the most concerning potential effects is an increased risk of serotonin syndrome, which is a rare but serious condition (4). Symptoms of serotonin syndrome can include confusion, increased blood pressure, fever, tremors and seizures.
Enhanced sedation
Both Celexa and Hydrocodone can cause drowsiness and sedation as side effects. When taken together, they may enhance these effects, leading to increased drowsiness, impaired coordination and slowed reaction times. This can be dangerous, especially when performing activities which require mental alertness.
Respiratory depression
Hydrocodone is an opioid medication that can slow down the respiratory system. When combined with Celexa it increases the risk of respiratory depression. Severe respiratory depression can be life-threatening.
Gastrointestinal effects
Both medications can cause gastrointestinal side effects like nausea or vomiting. Combining them may exacerbate these issues.
Always openly communicate with your healthcare provider about any concerns or unusual symptoms.
It is important to emphasize that not everyone will experience the effects and the severity of interactions can vary. It is essential to use Celexa and Hydrocodone under the guidance of a healthcare provider who can carefully monitor your response and adjust the dosages if needed.
How to ensure the safe use of Celexa and Hydrocodone together?
The following points should be considered to ensure the safe and effective use of Concerta and Hydrocodone together:
- Always take these medications as directed by your healthcare provider.
- Do not take both medications at the same time. If these medications are taken 2-3 hours apart, the risk of serotonin syndrome becomes relatively low.
- Do not consume alcohol while taking these medications as it can intensify the side effects.
- Unlike Celexa, Hydrocodone is a controlled substance. It can cause addiction if misused or taken more than the recommended dose. Never use it without consulting your healthcare provider.
- Inform your doctor about any side effects promptly. They may adjust the dosages of the two medications or may switch to another medication if required.
Always remember safe and effective use of medications is very important to get the desired therapeutic response.
Final thoughts
To sum up, there is a potential for interaction between Celexa and Hydrocodone. When taken together can lead to a life-threatening condition called serotonin syndrome, which requires immediate medical care; otherwise, it can be fatal.
Individuals on dual therapy with Celexa and hydrocodone should communicate with their healthcare provider. It promotes the careful management of the medication combination, aiming to achieve the best possible outcome while minimizing potential risks.
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