Does Carprofen make humans high? 

Does Carprofen make humans high? 

No, Carprofen does not make humans high or euphoric. Carprofen is a non-steroidal anti-inflammatory drug (NSAID) which is used in veterinary medicine

The drug is commonly used to treat arthritis pain in older dogs and horses. It is NOT manufactured for humans to take (1,2). There are a number of other NSAIDs which are available over the counter for you to take and you don’t need a veterinary NSAID for your symptoms. 

Carprofen was once used in humans – back in the 20th century – but it was taken off the market by its manufacturer brand because of commercial reasons and there were already plenty of other, better NSAIDs being manufactured, like Naproxen, Ibuprofen, etc. (3)

This is why Carprofen is only available as Rimadyl today, which is a veterinary medication. If you have pain and inflammation, you can purchase OTC Ibuprofen or Naproxen. 

As far as the state of euphoria caused by NSAIDs is concerned, these meds are not known for any such effect. 

Does Carprofen make animals high?

No, Carfrofen does not make animals high. It is not intended or designed to alter an animal’s mental state or induce a sense of intoxication or pleasure.

Instead, Carprofen works by reducing pain and inflammation in the body. It helps relieve discomfort and improve the overall well-being of animals, allowing them to move more comfortably and engage in normal activities (1,2).

It’s important to note that Carprofen is a medication prescribed by veterinarians for specific medical conditions in animals. The dosage and administration are carefully determined based on the animal’s size, weight, and health status. 

If you have specific concerns or questions about Carprofen or its effects on your pet, it’s always best to consult with a veterinarian. They can provide professional advice and address any specific concerns related to your animal’s health.

Common side effects of Carfrofen in animals

While generally considered safe when used as directed, Carprofen can have some potential side effects. Here are some common side effects you may observe in animals taking Carprofen:

  • Stomach Upset – leading to symptoms such as decreased appetite, vomiting, or diarrhoea. 
  • Increased Thirst and Urination 
  • Mild Behavioral Changes – including lethargy, drowsiness, or in rare cases, hyperactivity.
  • Liver and Kidney Effects (rare) – Signs of liver or kidney problems may include jaundice (yellowing of the skin or eyes), changes in urine output, or changes in drinking patterns.
  • Allergic Reactions (rare) – Signs of an allergic reaction may include swelling, hives, itching, difficulty breathing, or collapse.

It’s important to remember that not all animals will experience these side effects, and the severity and occurrence can vary. Your veterinarian will provide specific instructions for the safe use of Carprofen and monitor your pet’s response during treatment.

If you have any concerns or notice any unusual symptoms in your pet while taking Carprofen, it’s best to consult with your veterinarian. They can address your specific situation, provide guidance, and make any necessary adjustments to ensure the well-being of your pet.

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O’Brien WM, Bagby GF. Carprofen: a new nonsteroidal anti-inflammatory drug. Pharmacology, clinical efficacy and adverse effects. Pharmacotherapy. 1987 Jan-Feb;7(1):16-24. doi: 10.1002/j.1875-9114.1987.tb03500.x. PMID: 3554157.


Ghlichloo I, Gerriets V. Nonsteroidal Anti-inflammatory Drugs (NSAIDs). 2023 May 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 31613522.