Does Caladryl expire? 

Does Caladryl expire? 

Yes, Caladryl does expire. This cream usually comes with a shelf-life of about 3 years. Studies have shown that it can most likely outlive its expiration date. 

However, it is bound to become ineffective one day or another as the active ingredient present in Caladryl, Pramoxine, starts to lose its potency. 

This is why it’s best to stick to an unexpired Caladryl cream, especially if you’re disturbed because of the symptoms of your skin condition. 

What are the possible dangers associated with the use of expired Caladryl? 

Expired Caladryl is not dangerous to apply, but not effective either. The drug loses its efficacy and the safety profile also becomes uncertain. 

That’s the thing with expired medications and even the manufacturers don’t guarantee the effectiveness of the med once it is past the expiration date (1). This is why you should always opt for unexpired Caladryl. 

What to do if you have used expired Caladryl? 

If you have used a recently expired Caladryl, don’t worry. In fact, it will help you with your symptoms to some extent. However, if you have accidentally used a very old Caladryl and your symptoms seem a little exacerbated, reach out to your healthcare provider. 

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U.S. Food and Drug Administration. Don’t Be Tempted to Use Expired Medicines [Internet]. Silver Spring (MD): U.S. Food and Drug Administration; 2021 [cited 2022 Oct 24]. Available from: