Can you take Mucinex Multi-Symptom with Ibuprofen?
By
Dr Drielli Vital-Fujii (PhD)
Author bio
Dr Drielli Vital-Fujii, PhD, is a Pharmacist with expertise in Drug Design and Development, Enzymes, Molecular Modelling, and Photodynamic Therapy. She writes and reviews content on these topics.
Dr Drielli Vital-Fujii’s Highlights:
- Postdoctoral fellow at the Department of Biochemistry at the University of São Paulo, emphasizing therapy of neglected diseases using light.
- PhD in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Six months as an international researcher at the Center for Discovery and Innovation in Parasitic Diseases (University of California San Diego)
- Master’s degree in Pharmaceutical Sciences focusing on drug design and development at the Faculty of Pharmaceutical Sciences of the University of São Paulo.
- Bachelor of Pharmacy at the University of Mogi das Cruzes – São Paulo / Brazil
Professional Experience:
2012 – 2018 Project manager at University of São Paulo – Pharmacy Department
Dr Drielli Vital-Fujii has worked with computational studies, synthesis, biological evaluation, design, and development of new inhibitor candidates for Chagas Disease and Leishmaniasis.
2017 – 2017 International research fellow at University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences – Center for Discovery and Innovation in Parasitic Diseases.
She used Virtual Screening (VS) and High-Throughput Screening (HTS) Integration in the Discovery of new drugs against neglected tropical diseases (NTDs).
2018 – 2019 Faculdades Oswaldo Cruz
Dr Drielli Vital-Fujii was a professor in the Faculty of Pharmacy, teaching the subjects of Pharmaceutical Chemistry and Drug Development.
2019 – 2021 Researcher in Biochemistry University of São Paulo – Biochemistry Department
She applied Photodynamic Therapy in Leishmaniasis Treatment, mentored undergraduate students in scientific activities, and wrote, executed, translated, and reported scientific projects with funding agencies.
2023-2023 UniPiaget – University Center.
Dr Drielli Vital-Fujii was a Biology, Nutrition, Physiotherapy, and Pharmacy professor.
Education:
2018 -2021 Postdoctoral at the Department of Biochemistry at the University of São Paulo
2013 -2018 PhD of Science: Drugs and Medicines at Department of Pharmacy at University of São Paulo
2012 -2013 M.Sc. of Sciences: Drugs and Medicines at the Department of Pharmacy at the University of São Paulo
2005-2008 Bachelor of Pharmacy at the University of Mogi das Cruzes
The leading publications of Dr Drielli Vital-Fujii are:
Vital-Fujii, D.G, Baptista, M.S. (2021). Progress in the photodynamic therapy treatment of Leishmaniasis. Brazilian Journal of Medical and Biological Research, 54, 1-11.
Gatti, F. M., Gomes, R.A., da Fonseca, A.L., Lima, E.J.C., Vital-Fujii, D.G., Taranto, A.G., Varotti, F.P., Trossini, G.H.G. (2020). Antiplasmodial activity of sulfonylhydrazones: in vitro and in silico approaches. Future medicinal chemistry, 13, 233-250.
Silva, E.J., Bezerra-Souza, A., Passero, L.F., Laurenti, M.D., Ferreira, G.M., Fujii, D.G.V., et al. (2018). Synthesis, leishmanicidal activity, structural descriptors and structure-activity relationship of quinoline derivatives. Future medicinal chemistry, 10, 2069-2085.
Leite, F.H.A., Froes, T.Q., da Silva, S.G., de Souza, E.I.M., Vital-Fuji,i D.G., Trossini, G.H.G., et al. (2017). An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors. European Journal of Medicinal Chemistry, 132, 322-332.
Vital, D.G., Damasceno, F.S., Rapado, L.N., Silber, A.M., Vilella, F.S., Ferreira, R.S., et al. (2017). Application of bioisosterism in design of the semicarbazone derivatives as cruzain inhibitors: a theoretical and experimental study. Journal of Biomolecular Structure and Dynamics, 35, 1244–1259.
Mello, J. F.R., Gomes, R.A., Vital-Fujii, D.G., Ferreira, G.M., Trossini, G.H.G. (2017). Fragment-based drug discovery as alternative strategy to the drug development for neglected diseases. Chemical Biology & Drug Design, 90, 1067-1078.
Pantaleao, S.Q., Fujii, D.G.V., Maltarollo, V.G., da C. Silva, D., Trossini, G.H.G., Weber, K.C., et al. (2017). The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery. Medicinal Chemistry, 13, 706-720.
Vital, D., Arribas, M., Trossini, G. (2014). Molecular Modeling and Docking Application to Evaluate Cruzain Inhibitory Activity by Chalcones and Hydrazides. Letters in Drug Design and Discovery, 11, 249-255.
Blau, L., Menegon, R.F., Trossini, G.H.G., Molino, J.V.D., Vital, D.G., Cicarelli, R.M.B., et al. (2013). Design, synthesis and biological evaluation of new aryl thiosemicarbazone as antichagasic candidates. European Journal of Medicinal Chemistry, 67, 142-151.
You can view some of Dr Drielli’s work below and links to her professional profile.
Orcid: https://orcid.org/0000-0001-9270-0466
Research Gate: https://www.researchgate.net/profile/Drielli-Gomes-Vital-Fujii
Scopus: https://www.scopus.com/authid/detail.uri?authorId=55829534000
Google Scholar: https://scholar.google.com/citations?user=F9U50AEAAAAJ&hl=pt-BR
Linkedin: linkedin.com/in/driellivital
Escavador: https://www.escavador.com/sobre/6101380/drielli-gomes-vital
CDIPD: https://cdipd.org/index.php/about-us/visiting-scientists
Can you take Mucinex Multi-Symptom with Ibuprofen?
Yes, you can take Mucinex Multi-Symptom with Ibuprofen, as there are no known interactions between these two. Ibuprofen is a painkiller and anti-inflammatory agent which also helps to reduce fever. Mucinex Multi-Symptom contains three active ingredients:
- Guaifenesin
- Dextromethorphan
- Phenylephrine
None of these ingredients reacts with Ibuprofen. However, some Mucinex Multi-Symptom like Mucinex Multi-Symptom cold nighttime formula and Mucinex Multi-Symptom cold & fever already contain Acetaminophen, which is also a painkiller and fever reducer (1,2).
If you’re using the one with Acetaminophen, you may not need to use Ibuprofen as Mucinex will most likely do the job on its own. The original Mucinex formulation is frequently paired with Acetaminophen (Tylenol), as it only contains Guaifenesin.
However, if you have severe pain or you’re taking them at different times, it is okay to use these formulations together. But again, mild body pain associated with cold and fever does not require two painkillers.
However, Ibuprofen is not only a painkiller, but it also reduces inflammation – which makes it more effective than Acetaminophen in some cases.
Potential benefits of taking Mucinex Multi-Symptom with Ibuprofen
Some benefits of combining Mucinex Multi-Symptom and Ibuprofen include (1,2):
Comprehensive relief
As stated earlier, Mucinex Multi-Symptom contains a combination of ingredients to address multiple cold and flu symptoms like congestion, cough, and sore throat.
When combined with Ibuprofen, it can provide additional relief from fever, headache, and body aches, offering a more comprehensive approach to managing your symptoms.
Reduced inflammation
Ibuprofen helps to reduce inflammation, which can ease discomfort in the throat, sinuses, and other affected areas. This can lead to improved comfort and an overall sense of relief during illness.
Potential risks of taking Mucinex Multi-Symptom with Ibuprofen
Some risks of combining Mucinex Multi-Symptom and Ibuprofen include (1,2):
Overmedication
Using multiple medications that target similar symptoms may lead to unintentional overmedication, as some ingredients could overlap. This may increase the risk of side effects or adverse reactions.
Gastrointestinal upset
Both Mucinex Multi-Symptom and Ibuprofen can cause stomach irritation or upset. Taking them together may exacerbate this side effect.
Allergic reactions (Rare)
Some individuals may be allergic to specific components of Mucinex Multi-Symptom or Ibuprofen. Using them together may increase the risk of an allergic reaction.
Final words
In conclusion, while taking Mucinex Multi-Symptom with Ibuprofen may provide comprehensive relief for cold and flu symptoms, it is essential to be cautious about potential interactions and side effects.
Always consult with a healthcare professional or pharmacist before combining medications and follow their recommended dosages to ensure safe and effective symptom management. If you experience any adverse effects while using these medications together, seek medical advice promptly.
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References
1.-
Ngo VTH, Bajaj T. Ibuprofen. 2023 May 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 31194439. https://www.ncbi.nlm.nih.gov/books/NBK542299
2.-
LABEL: MUCINEX MAXIMUM STRENGTH- guaifenesin tablet, extended-release. DailyMed [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=47f5323c-ee3a-400d-b133-31d9c286fafd&type=pdf
