Can you take Mirtazapine and Valium together?

In this article, we will discuss the concomitant use of Mirtazapine (Remeron) and Diazepam (Valium). We will talk about the potential benefits and risks of this combination and some suitable alternatives.

Can you take Mirtazapine and Valium together?

You can take Mirtazapine and Valium together if your healthcare provider has prescribed them. The combination of Mirtazapine and Valium might not always be the best, as both medications may cause overlapping effects on the brain (1,2). 

Furthermore, dosage adjustment plays a crucial role with such combinations, as they have to be carefully decided to remain within the safe range while taking this combination. 

This is why you should stick to your doctor’s directions when using a combination of medications that can affect your brain – such as Mirtazapine and Valium, an antidepressant and an anti-anxiety medication respectively.

What are the potential benefits of taking Mirtazapine and Valium together?

The combination of Mirtazapine and Valium may offer potential benefits for some individuals. Mirtazapine, being an antidepressant, can help several symptoms of depression (1). 

It can also help with anxiety and insomnia. Valium, on the other hand, is a benzodiazepine which can also be used for anxiety and insomnia (2). 

When their doses are adjusted or if they are spaced out properly, the combination may help some people deal with a variety of mental health symptoms. 

However, both of these meds can work on similar symptoms – which does not always mean increased efficiency. Such combinations sometimes become a bit too much to handle, especially for people who have underlying factors affecting their health.

What are the potential risks of taking Mirtazapine and Valium together?

The combination of Mirtazapine and Valium is associated with some potential health risks, especially if the doses are not adjusted well. These may include: (3,4)

• Increased sedation
• Dizziness
• Impaired coordination
• Confusion
• Slurred speech
• Risk of falls/injury

These side effects can vary from person to person, depending on factors like an individual’s age, doses, use of other medications, and any pre-existing disease. 

What are the alternatives to taking Mirtazapine and Valium together?

There are some alternatives to taking Mirtazapine and Valium together. If Mirtazapine monotherapy isn’t effective or it does not manage your symptoms adequately, your doctor might consider combining it with other medications.

Antidepressants like selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) can help enhance the effects of Mirtazapine – like Sertraline or Duloxetine can be paired with Mirtazapine sometimes for severe depression. 

However, these combinations don’t always work; their effectiveness can vary from person to person, as what works for one may not always work for another. 

One good thing about these combinations is that they can be used for an extended period, unlike Valium, a controlled substance that isn’t suitable for long-term use due to the risk of tolerance and addiction.

However, the best alternative treatment should be determined by your healthcare provider. Sometimes, behavioural therapy can be a valuable addition to your treatment plan. This can help enhance the behavioural benefits of antidepressant monotherapy.

It’s essential to work closely with your doctor to find the most suitable treatment approach for your condition.

Conclusion

In this article, we have discussed the concomitant use of  Mirtazapine and Valium. We have also talked about some benefits and risks of this combination, and how people should always follow their doctor’s directions when it comes to therapeutic combinations like this one.

References

1. Jilani TN, Gibbons JR, Faizy RM, Saadabadi A. Mirtazapine. 2022 Sep 7. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 30085601. https://pubmed.ncbi.nlm.nih.gov/30085601/

2. Dhaliwal JS, Rosani A, Saadabadi A. Diazepam. 2022 Sep 3. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 30725707. https://www.ncbi.nlm.nih.gov/books/NBK537022

3. National Library of Medicine. Mirtazapine: MedlinePlus Drug Information [Internet]. Bethesda (MD): U.S. National Library of Medicine. Available from: https://medlineplus.gov/druginfo/meds/a697009.html 

4. National Library of Medicine. Diazepam: MedlinePlus Drug Information [Internet]. Bethesda (MD): U.S. National Library of Medicine. Available from: https://medlineplus.gov/druginfo/meds/a682047.html