Can you take Luvox for depression? (+3 findings)

In this article, we will discuss whether or not Luvox can be used to treat depression, how Luvox can be used to treat depression, research studies supporting this evidence, potential side effects of Luvox, what to do if Luvox is not helping your depression, and safety considerations when taking Luvox for depression.

Can you take Luvox for depression?

Yes, Luvox can be used to treat MDD (Major Depressive Disorder). Luvox is the brand name of the medication fluvoxamine.

It is a member of the group of drugs called SSRIs (Selective Serotonin Reuptake Inhibitors), which function by raising serotonin levels in the brain. Serotonin is a natural neurotransmitter that affects mood, hunger, and sleep. (1)

Luvox can help patients with MDD feel better emotionally, experience less anxiety, and have a higher quality of life overall by raising serotonin levels.

It’s crucial to remember that antidepressants like Luvox can take several weeks to start working and it’s important to follow your healthcare provider’s guidelines for dose and duration of treatment in order to get the best results.

How can Luvox treat depression?

Luvox’s mechanism of action in increasing serotonin levels can help treat depression. Serotonin is a neurotransmitter that controls mood, appetite, and sleep.

The brain chemicals including serotonin are frequently low in depressed patients. Blocking serotonin’s reuptake raises serotonin levels in the brain, which relieves depression symptoms. This is how Luvox works. (2)

After taking Luvox, the body needs four to six weeks to reach a therapeutic level. Many patients report a decrease in depression symptoms, such as anxiety, irritability, poor mood, difficulty sleeping, or worthlessness after taking Luvox.

What does research suggest?

A research study was conducted to evaluate the efficacy of fluvoxamine maleate (Luvox) as a depression medication. 150 depressed outpatients were randomly assigned to a 6-week, double-blind therapy regimen consisting of 50-150 mg of fluvoxamine maleate.

When compared to placebo, fluvoxamine showed a considerable therapeutic benefit. Fluvoxamine was shown to be well-tolerated and safe. However, the fluvoxamine group experienced increased release-abnormalities, nausea, and somnolence. Most of these side effects were mild to moderate and transient.

The results unequivocally showed that fluvoxamine maleate at a dose of 50-150 mg per day has antidepressant action and is as tolerable as a placebo and that fluvoxamine can be used effectively in treating MDD (Major Depressive Disorder). (3)

What is the recommended Luvox dose for treating depression?

The recommended Luvox doses for treating depression range between 50-150mg per day. The maximum daily dose is 300 mg per day. Collaborating carefully with your healthcare provider to ascertain the appropriate dosage is also crucial. (4)

Some individuals could respond better to a lower dose, while others might require a greater dose. It’s crucial to take Luvox exactly as directed and to avoid making any modifications or discontinuing the medication without first consulting your healthcare provider.

What are the potential side effects of Luvox?

There are several side effects that can occur while taking Luvox. Examples include: (1)

Common side effects

  • Xerostomia (dry mouth).
  • Nausea and vomiting.
  • Abdominal pain.
  • Constipation.
  • Sexual dysfunction.
  • Insomnia (inability to sleep).
  • Sweating.
  • Diarrhea.

Serious side effects

  • Long-lasting confusion and dizziness.
  • Numbness and tingling in any body parts.
  • Difficulty concentrating.
  • Excessive bleeding in any bodily parts such as gums bleeding, coughing up blood, blood in the urine or feces, or irregular menstrual cycle.
  • Seizures.
  • Muscle stiffness.
  • Arrhythmia or irregular heartbeats.

If you experience any of these adverse effects, seek medical attention immediately. Your healthcare provider will properly assess your situation and take the best course of action accordingly.

Who should not use Luvox to treat depression?

It’s important to note that some individuals should avoid using Luvox for depression treatment. These include: (2)

  • Individuals who have a history of bipolar disorder as Luvox can trigger manic episodes.
  • Individuals who have taken a MAOI (Mono-Amine-Oxidase Inhibitor) within the last 14 days, as this can lead to dangerous interactions.
  • Individuals who have a history of seizures, as Luvox can increase the risk of seizures.
  • Individuals who have a history of Liver disease, as Luvox can cause liver damage in rare cases.
  • Pregnant and breastfeeding women, as Luvox may be harmful to the developing fetus or infant.

What to do if Luvox is not helping your depression?

If Luvox is not helping in treating your depressive symptoms, consult your healthcare provider about increasing your dose or switching to an alternative such as: (5)

Sertraline: It is an SSRI antidepressant sold under the brand name Zoloft and is effective in treating depression symptoms.

Paroxetine: It is an SSRI antidepressant, marketed under the brand name Paxil, and is used to treat depression and OCD (Obsessive Compulsive Disorder).

Fluoxetine: It is an SSRI antidepressant that was shown effective in treating depression, marketed under the brand name Prozac. If you experience side effects from using paroxetine (Paxil), your healthcare provider can switch you to Prozac.

Based on research, these antidepressants were shown to be effective in treating depression and caused fewer adverse effects than fluvoxamine.

What precautions should you take when using Luvox for depression?

There are several precautions that you should take when using Luvox such as: (1)

  • You should never abruptly discontinue Luvox, as this may result in withdrawal symptoms such as anxiety, nausea, vomiting, and diarrhea. If you want to discontinue the medication, consult your healthcare provider about gradually reducing your dose.
  • Steer clear of alcohol while using Luvox, as using alcohol may exacerbate adverse effects.
  • Inform your healthcare provider about any concomitant medications or herbal supplements that you take in order to reduce and avoid possible drug interactions.
  • Inform your healthcare provider about any underlying medical conditions that you have such as Liver, kidney, or heart diseases.
  • Contact your healthcare provider immediately if you experience any suicidal thoughts while taking Luvox.
  • Steer clear of smoking as this can exacerbate Luvox’s side effects.

Based on my knowledge and research, Luvox is used to treat depression. However, if you find this drug ineffective in treating your depression symptoms or causing side effects, consult your healthcare provider about reducing your medication dose or switching to an alternative with fewer adverse events.

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LUVOX® (Fluvoxamine Maleate) Tablets 25 mg, 50 mg and 100 mg Suicidality and Antidepressant Drugs [Internet]. Available from:


Claghorn JL, Earl CQ, Walczak DD, Stoner KA, Wong LF, Kanter D, et al. Fluvoxamine Maleate in the Treatment of Depression. Journal of Clinical Psychopharmacology. 1996 Apr;16(2):113–20. Available from:,patients%20with%20major%20depressive%20disorder.


Morishita S, Arita S. Suitable dose and duration of fluvoxamine administration to treat depression. Psychiatry and Clinical Neurosciences. 2003 Apr;57(2):177–81. Available from:


Mackay FJ, Dunn NR, Wilton LV, Pearce GL, Freemantle SN, Mann RD. A comparison of fluvoxamine, fluoxetine, sertraline and paroxetine examined by observational cohort studies. Pharmacoepidemiology and Drug Safety. 1997 Jul;6(4):235–46. Available from:

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