Can you split Jardiance in half?

Can you split Jardiance in half?

It is not recommended by the manufacturer of Jardiance to cut or split the tablets in half. Although Jardiance is not a controlled-release dosage form, it is manufactured as film-coated tablets (1). 

The coating can be done for a number of reasons, like masking the bitter taste of the drug or enhancing its stability during the shelf-life. If you split such a tablet, you will end up disrupting the film (1). 

However, Jardiance is quite expensive and tablet splitting may come to one’s mind to cut the cost of the med, as not every person can easily afford it. The best thing to do here is to talk to your healthcare provider. If your doctor recommends splitting the tablet, you can do it. 

Potential risks of splitting Jardiance in half

Splitting Jardiance, or any medication, in half without proper guidance from a healthcare professional can pose potential risks: (1,2)

  • Uneven dosage: Splitting the tablet may result in uneven halves, leading to an inaccurate dose. This can affect the medication’s effectiveness in treating your condition.
  • Reduced effectiveness: Breaking the tablet may alter its structure, affecting its ability to release the drug as intended. This could reduce the medication’s effectiveness in managing your medical condition.
  • Increased risk of side effects: If the medication is not evenly divided, one-half might contain more of the active ingredient, leading to an increased risk of side effects or adverse reactions.
  • Decreased shelf life: Once the tablet is split, its stability may be compromised, reducing its shelf life and potentially rendering it ineffective if stored for an extended period (2).

Alternatives to splitting Jardiance in half

If your healthcare provider has prescribed a specific dose of Jardiance that cannot be split, there are alternatives to consider instead of attempting to divide the medication. 

Firstly, you can discuss with your doctor the possibility of prescribing a lower-dose tablet of Jardiance that matches your required dose. This way, you can avoid the need for splitting the tablet and ensure accurate dosing.

For those who have trouble swallowing the tablet whole, alternative formulations may also be considered. Your healthcare provider might recommend other medications with similar benefits that are available in alternative forms, such as liquids or dissolvable tablets.

Remember, it’s crucial to communicate openly with your doctor to ensure you receive the right treatment without compromising your health or safety.

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LABEL: JARDIANCE- empagliflozin tablet, film-coated. DailyMed [Internet]. Available from:


Food and Drug Administration (FDA). Best Practices for Tablet Splitting. Available from: