Can you cut Eliquis in half? 

Can you cut Eliquis in half?

Yes, you can cut Eliquis (Apixaban) in half. According to the Food and Drug Administration (FDA), Eliquis tablets are safe to crush and you can add them to glucose solution, apple juice, or applesauce for ease of administration. 

This usually happens because some people may find it difficult to swallow the tablets whole and some may try to reduce the dose. 

Risks of cutting Eliquis in half

The biggest concern with cutting Eliquis tablets in half is to make sure you’re cutting them into two equal halves and that you’re protecting them well against moisture. 

Eliquis tablets are film-coated, which protects them from the damage that moisture penetration may cause. Film-coating also helps mask the bitter taste of the drug, which may otherwise become quite unpleasant. 

If you’re cutting these tablets, you need to make sure that you’re taking it immediately, and placing the other half in a secure place to protect it from moisture. 

How to ensure the safe use of crushed Eliquis tablets?

If you have decided to crush your Eliquis tablets, you need to do it right away. The first and most important thing to make sure of is to never store crushed tablets for later use. Crush as much as you need to take in a single dose and right when you’re about to take it. 

The next dose should be crushed when it’s time for your next dose and not before that. It’s not safe to consume crushed Eliquis 3-4 hours after mixing it with juice or liquid. 

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Apixaban (National Library of Medicine, NIH)