Can you crush Naproxen? 

Can you crush Naproxen? 

You can crush regular immediate-release versions of Naproxen and mix it with foods like applesauce or pudding for ease of administration. However, you need to make sure you consume the entire medication and that no powder is left. 

Although it is generally considered okay to crush immediate-release tablets as long as you’re doing it the right way, it’s still best to switch to an alternative dosage form that you can easily consume. 

However, Naproxen is also available as an extended-release and gastro-resistant tablet. Such dosage forms should never be cut or crushed(1)

Risks associated with crushing modified-release Naproxen formulations

Extended-release Naproxen tablets are designed in such a way that they release Naproxen over an extended period of time and the entire drug is not released at once. 

If you break or crush such a tablet, the extended-release mechanism will be ruined and it can cause more pronounced side effects. 

Gastro-resistant Naproxen tablets, on the other hand, are enteric-coated tablets which do not disintegrate in your stomach. The coating dissolves and releases the drug in your intestines, which provides a basic/alkaline medium. 

This can help prevent gastrointestinal side effects from Naproxen, as the drug does not come in contact with your stomach this way. 

So make sure you don’t crush such dosage forms. It’s always best to ask your doctor or pharmacist for a better alternative if you find it difficult to consume entire tablets. 

Alternatives to crushing Naproxen

It is best to ask your doctor or pharmacist for a suitable alternative before you start crashing Naproxen tablets. Naproxen is also available in the form of liquid, and you can ask your pharmacist for an oral liquid alternative if you find it difficult to swallow tablets. 

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PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 156391, Naproxen. Available from: