Can Paxil hurt a dog? (3+Factors)
By
Ivan Kahwa
Author bio
Mr Ivan Kahwa is a chemist and phytopharmaceutical scientist with expertise in chemistry, pharmacology, phytochemistry, and Nanobiotechnology. He writes and reviews content on these topics.
Mr Ivan Kahwa’s Highlights:
Guest Researcher at the University of Leipzig, Senior Research Fellow/Scientist, and Lecturer at the Department of Pharmacy, Faculty of Medicine, Mbarara University of Science and Technology.
Professional Experience:
Mr Ivan joined PHARMBIOTRAC as a research fellow/scientist during his master of science tenure. He contributed to the development of most of the phytopharmaceutical products in the project. Furthermore, he participated in carrying out the pharmacological activities of the developed products in laboratory animals such as mice and rats in order to develop proper doses hence leading to pre-clinical studies.
With the above relevant research experience, Ivan started to work with the University of Leipzig on collaborative projects with Mbarara University to develop the chemistry of Ugandan Medicinal plants and their pharmacological activities. This was coupled with several consultative positions by different German NGOs. Mr. Kahwa is also a supporting in the teaching and learning at the Departments of Pharmacy and Pharmaceutical Sciences, Faculty of Medicine, Mbarara University of Science and Technology.
With the increase in antimicrobial resistance globally, Ivan retooled his thinking towards developing new naturally derived antibiotic regimens from Ugandan propolis with the assistance of nanotechnology to improve their delivery to microbial cells. Kahwa has also published over 28 articles in peer-reviewed journals and he is currently reviewing for many journals.
Education:
2023-2027: PhD in Pharmaceutical Sciences (ongoing) with a focus on Pharmaceutical Microbiology and Nanobiology at Mbarara University of Science and Technology.
2022: 2Msc. in Pharmacognosy and Natural Medicine Science at Mbarara University of Science and Technology.
2018: Bachelor of Science (Chemistry) at Mbarara University of Science and Technology.
Publications:
▪ Iqbal, S., Jabeen, F., Kahwa, I., & Omara, T. 2023. Suberosin Alleviates Thiazolidinedione-Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4-LPCAT3 and PI3K-AKT Signaling Pathways. Cardiovascular Toxicology. https://doi.org/10.1007/s12012-023-09804-7
▪ Gupta, A. K., Yadav, R., Sharma, S., Sawale, J., & Kahwa, I. 2023. Anti-ageing Activity and Antioxidant Activity of Methanol Extracts of Leaves and Flowers of Salvia officinalis and Rosmarinus officinalis. Journal of Young Pharmacists, 15(3), 448–455. https://doi.org/10.5530/jyp.2023.15.60
▪ Tolo, C.U., Kahwa, I., Nuwagira, U., Weisheit, A. and Ikiriza, H., 2023. Medicinal plants used in treatment of various diseases in the Rwenzori Region, Western Uganda. Ethnobotany Research and Applications, 25, pp.1-16.
https://ethnobotanyjournal.org/index.php/era/article/view/4683
▪ Kahwa, I., Ajayi, C.O., Yadav, R., Chauhan, N.S., Shah, K., Abdelgadir, A.A., Shegena, E.A., Daniel, S., Omara, T., Asiimwe, J.B. and Ikiriza, H., 2023. Pharmacognostic and phytochemical studies as an invaluable approach for correct identification of medicinal plants: The case of Artemisia vulgaris L. substituted for Artemisia annua L. in Western Uganda. TMR Integr Med, 7, p.e23004.
https://doi.org/10.53388/TMRIM202307004
▪ Nalimu, F., Oloro, J., Kahwa, I. and Ogwang, P.E., 2021. Review on the phytochemistry and toxicological profiles of Aloe vera and Aloe ferox. Future Journal of Pharmaceutical Sciences, 7, pp.1-21.
https://doi.org/10.1186/s43094-021-00296-2
▪ Elamin, O.H.S., Ali, M.A., Elgezuli, I.A.A., Bashir, M.A. and Kahwa, I., 2021. Diagnosis of pre-and post-treatment of echinococcus granulosus with counter current immune electrophoresis and bacterial co-agglutination. Journal of Microbiology and Infectious Diseases, 11(02), pp.88-94.
https://doi.org/10.5799/jmid.951600
Published book Chapter
▪ Kahwa, I., Ayesiga, I., Nakalema, S., Alinaiswe, R., Mbabazi, R. and Iqbal, S., 2023. Natural products in the management of onchocerciasis. In Natural Products in Vector-Borne Disease Management (pp. 63-80). Academic Press. Book Chapter.
https://doi.org/10.1016/B978-0-323-91942-5.00012-4
Submitted manuscripts Under Review:
▪ Comparison of the Wound Healing Activity of the Leaf and Leaf Ash Extracts of Vernonia amygdalina in Rats. Journal name: Clinical Phytoscience
▪ Ethnobotanical Survey of Medicinal plants used in the management of cancer in Uganda. Journal name: Journal of Herbal Medicine
▪ Ethnobotanical survey and phytochemical screening of medicinal plants used in treatment of epilepsy by PROMETRA-Uganda Traditional Health Practitioners in Mpigi District, Uganda. Journal name: Journal of Ethnopharmacology
Submitted book chapters under review
1.Book title: Algae as a Natural Solution for Water-Food-Energy Nexus, Section 4: Microalgae and cyanobacteria for food applications, Chapter 4.6: Safety, toxicological and allergenic aspects of using algae for food. Authors: Christine Kyarimpa, Tom Omute, Caroline K. Nakiguli, Alice V. Khanakwa4, Christopher Angiro, Ivan Kahwa, Fortunate Ahumuza, Timothy Omara*. Publisher: Springer Nature Singapore Pte Ltd. 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore.
2.Book title: Nutraceuticals Inspiring the Contemporary Therapy for Lifestyle Diseases. Chapter: Nutraceutical applications of Seaweeds and their Phytocompounds in Nutrition and Treatment of Diseases. Authors: Ivan Kahwa, Timothy Omara , Innocent Ayesiga , Gael Noel Neh Neba Ambe , Zehbanaz Javidbhai Panwala , Rachel Mbabazi , Shabnoor Iqbal , Christine Kyarimpa , Christine Betty Nagawa , Kamal Shah ,Nagendra Singh Chauhan* Publisher: CRC Press
You can view my works on the following professional sites:
Research Gate: https://www.researchgate.net/profile/Ivan-Kahwa
Google Scholar: https://scholar.google.com/citations?user=tOwrvqoAAAAJ&hl=en
ORCID: https://orcid.org/0000-0002-6440-3437
Linkedin: https://de.linkedin.com/in/ivan-kahwa-865450159
This article will explore the potential harm of Paxil to dogs, outlining how it can be detrimental. It will also cover the signs of toxicity, emphasising the prompt action after ingestion.
Can Paxil hurt a dog?
Yes, Paxil can hurt dogs if ingested. Pets especially dogs have adverse reactions to human medications due to differences in metabolism and tolerance levels. If a dog ingests Paxil, immediate veterinary attention is crucial to prevent potential complications and ensure the best possible care for the pet’s well-being (1).
What signs indicate Paxil toxicity in dogs?
Paxil toxicity in dogs can manifest through a range of symptoms. Gastrointestinal distress, including vomiting and diarrhoea, might occur initially indicating the body’s attempt to expel the toxic substance. These signs often indicate an overdose or adverse reaction to Paxil (2).
Dogs may also exhibit an increased heart rate, agitation, and restlessness. Tremors or muscle twitching could become noticeable, along with dilated pupils and changes in body temperature presenting as fever. In severe cases, the dog might display seizures or collapse.
These symptoms collectively indicate a toxic reaction to Paxil, highlighting the urgency for immediate veterinary attention. Recognizing these signs promptly becomes crucial for pet owners as early intervention significantly improves the chances of successful treatment and recovery for dogs affected by Paxil toxicity.
What to do if your dog consumes Paxil?
If your dog has ingested Paxil, taking immediate action is crucial for their well-being. Contact your veterinarian or an emergency veterinary clinic without delay or you can take these immediate steps (3):
Do Not Induce Vomiting
Unless specifically instructed by a veteran, refrain from inducing vomiting in your dog. It is essential to seek professional guidance before attempting any home remedy to ensure the best course of action for your dog’s health.
Avoid Home Remedies
Refrain from administering any home remedy without veterinary advice, as these could potentially worsen the situation for your dog. Some well-intended remedies might not be suitable for your pet’s condition and certain medications interact negatively with Paxil.
Monitor Your Dog
Keep a close eye on your dog’s behaviour and physical condition after ingesting Paxil. Watch for any unusual symptoms such as vomiting, diarrhoea, changes in breathing, agitation tremors, or unusual lethargy. Note the time of ingestion and any observable changes to provide crucial information to the veterinarian.
What veterinary treatments are administered for Paxil poisoning in dogs?
The overdose of Paxil creates poisoning in humans as well as dogs. Therefore, immediate veterinary interventions tailored to address the specific effects after toxic exposure are very important. Here are some methods (4):
Decontamination
The vet may initiate decontamination by inducing vomiting Vomiting aims to expel any remaining Paxil from the stomach if the ingestion occurred recently. Activated charcoal helps absorb toxins, preventing their further absorption into the bloodstream.
Supportive Care
Intravenous fluids are often administered to maintain hydration and aid in flushing out the toxins. Monitoring irregulating vital signs such as temperature, heart rate, and blood pressure are essential components of supportive care to stabilize the dog’s condition.
Monitoring and Observation
Continuous monitoring is crucial to detect and manage any emerging complication or adverse reaction resulting from Paxil poisoning. Observation of changes in behaviour, neurological symptoms, or organs of this dysfunction is essential.
Symptoms Management
To address specific symptoms triggered by Paxil toxicity, the veterinarian may provide medications to manage seizures, tremors, elevated heart rate, or other observable signs (5).
Professional Oversight
Close supervision by veterinary professionals ensures comprehensive care, quick intervention in case of complication, and ongoing adjustment to the treatment plan based on the dog’s response to therapy.
In my experience, recognizing signs of Paxil toxicity in dogs, understanding urgent post-ingestion steps, and grasping the importance of vet care for Paxil poisoning are crucial for keeping our pets safe and healthy.
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References
1.-
Schillace BL. Kimberly K. Emmons, Black Dogs and Blue Words: Depression and Gender in the Age of Self-Care: Rutgers University Press, New Brunswick, NJ, 2009, 232 pp. Available from: https://link.springer.com/article/10.1007/s11013-011-9223-1
2.-
Pros P. Dog anxiety medication. Available from: https://doganxiety.com/dog-anxiety-medication/
3.-
Wismer TA. Antidepressant drug overdoses in dogs. Veterinary Medicine. 2000 Jul 1;95:520-5.Available from:https://www.researchgate.net/profile/Tina-Wismer/publication/237718271_Antidepressant_overdoses_in_dogs/links/00b495395fb9c3b948000000/Antidepressant-overdoses-in-dogs.pdf
4.-
Simpson BS, Papich MG. Pharmacologic management in veterinary behavioral medicine. Veterinary Clinics: Small Animal Practice. 2003 Mar 1;33(2):365-404.Available from:https://www.vetsmall.theclinics.com/article/S0195-5616(02)00130-4/abstract
5.-
Harder B. Pushing Pills.Available from: https://link.springer.com/article/10.1007/s11013-011-9223-1
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