Can Lactaid cause constipation? (+5 factors)

In this article, we will discuss whether Lactaid can cause constipation or not. we will further look at the factors that may lead to constipation due to Lactaid treatment. Furthermore, we will discover other methods for the intake of lactose products by lactose intolerants.

Can Lactaid cause constipation?

Lactaid may cause constipation. Taking lactase supplements such as Lactase is not commonly associated with causing constipation. However individual patient sensitivity and variation may cause constipation in a few patients taking Lactaid. 

Lactase is an enzyme responsible for the digestion of lactose (milk sugar). The deficiency of lactase enzyme causes lactose intolerance in patients who are given Lactaid supplements to overcome this deficiency (1).

Constipation is commonly referred to as hard and infrequent bowel movements. Constipation is characterized by large and painful stools with fecal incontinence and abdominal pain (2). 

Lactose intolerant patients can take Lactaid supplements to easily digest milk or milk products. Lactaid is a non-prescription and over-the-counter supplement. Without Lactaid supplements, lactose intolerant patients suffer from bloating, gas, and diarrhea upon ingesting milk products. 

What does research suggest?

Research studies suggest that lactose-intolerant patients commonly suffer from constipation, particularly children. About 30% of lactose-intolerant patients have reported constipation (2). 

Lactose is a milk sugar that is present in milk or dairy products. Lactase is an enzyme naturally present to break this milk sugar in D-glucose and D-galactose which are easily absorbed from the intestine (2). 

Lack of lactase is not commonly accompanied by constipation. Similarly, taking Lactaid supplements is also not associated with causing constipation in lactose-intolerant patients unless they have some underlying conditions or are taking concomitant medications. 

How to know if you have lactose intolerance?

Lactose intolerance is commonly characterized by the following symptoms which may last from 30 minutes to 2hours after consuming any dairy product (2,3):

  • Abdominal pain
  • Bloating
  • Flatulence
  • Borborygmus
  • Nausea 
  • Vomiting
  • Constipation (Less frequent)

However, it is important to note that not all lactose-intolerant patients suffer from the same intensity of these side effects. Different patients have different levels of symptom severity based on individual patient variation. 

If you suffer from such symptoms after consuming dairy products then you must consult your healthcare provider. They must perform certain tests to properly diagnose lactose intolerance and once diagnosed they can suggest you take Lactaid supplements. 

What factors can cause constipation while taking Lactaid?

The following factors may contribute to constipation while taking Lactaid:

  • Individual patient variation- Some patients may be more sensitive to Lactaid supplements which may react to them resulting in constipation. 

 

  • Inactive ingredients- The inactive ingredients in Lactaid pills might not suit some patients and result in constipation and abdominal discomfort. 

 

  • Fiber intake- Dietary fiber plays an important role in constipation. Taking Lactaid supplements and having a low daily fiber intake may cause constipation in some patients.

 

  • Hydration- A sufficient amount of water intake is also essential to prevent constipation. To ensure healthy bowel movements along with Lactaid supplements, you must intake plenty amount of fluids. 

 

  • Concomitant medications- Taking concomitant medications such as duloxetine or trazodone, then you must discuss this with your doctor because these medications commonly cause constipation. 

What are the potential side effects of Lactaid? 

Lactaid pills are generally not associated with causing severe side effects. However, the following potential side effects may occur (4):

  • Anaphylaxis
  • Skin rash
  • Hives
  • Hoarseness
  • Chest tightness
  • Difficulty in breathing

If you have an underlying condition or if you are taking concomitant medications along with Lactaid, then talk to your doctor regarding the safety of your health. 

What to do if you suffer from constipation while taking Lactaid?

If you suspect that Lactaid is causing constipation, then you must discontinue its use. You can consult a healthcare professional for a detailed examination and to figure out the exact cause of constipation. 

If constipation is due to Lactaid supplements, then your doctor must discontinue their use and suggest you improve dietary fiber and increase fluid intake in your diet to get rid of constipation. 

Your doctor may also suggest some alternative ways to overcome lactose intolerance such as (5):

  • Probiotics
  • Fermented milk

In my experience

Being a pharmacist, I would advise that if you suffer from constipation while taking Lactaid pills, then talk to your doctor. They must find a middle way between lactose intolerance and digestive comfort relieving constipation. 

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References

1.-

Stourman N, Moore J. Analysis of lactase in lactose intolerance supplements. Biochem Mol Biol Educ. 2018 Nov;46(6):652-662. doi: 10.1002/bmb.21185. PMID: 30462373. https://pubmed.ncbi.nlm.nih.gov/30462373/

2.-

Leszkowicz J, Plata-Nazar K, Szlagatys-Sidorkiewicz A. Can Lactose Intolerance Be a Cause of Constipation? A Narrative Review. Nutrients. 2022 Apr 24;14(9):1785. doi: 10.3390/nu14091785. PMID: 35565753; PMCID: PMC9105309. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105309/

3.-

MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); [updated 2020 Jun 24]. Lactose intolerance [updated 2020 Jun 10; reviewed 2016 Aug 25; cited 2020 Jul 1]; [about 5 p.]. Available from: https://medlineplus.gov/genetics/condition/lactose-intolerance/

4.-

Voisin, M.R., Borici-Mazi, R. Anaphylaxis to supplemental oral lactase enzyme. Allergy Asthma Clin Immunol 12, 66 (2016). https://doi.org/10.1186/s13223-016-0171-8

5.-

Ibrahim SA, Gyawali R, Awaisheh SS, et al. Fermented foods and probiotics: An approach to lactose intolerance. Journal of Dairy Research. 2021;88(3):357-365.  https://www.cambridge.org/core/journals/journal-of-dairy-research/article/fermented-foods-and-probiotics-an-approach-to-lactose-intolerance/