Can you use expired Neomycin ear drops? 

Can you use expired Neomycin ear drops?

No, it is not recommended to use expired Neomycin ear drops for an active ear infection. Expired antibiotics have no guarantee regarding their safety and efficacy and should not be considered for symptomatic bacterial infection. 

Although unopened Neomycin ear drops can remain good for 1-2 years during their shelf-life, once they are opened, discard the unused solution within a month or two. 

What are the possible dangers associated with the use of expired Neomycin ear drops? 

Expired Neomycin ear drops are not a good solution for an active bacterial infection as the formulation loses its potency with time. This can result in therapeutic failure and you will not see an improvement in your symptoms. 

Ear infections can be quite painful and they should not be left untreated. Not only this, but several research studies have also reported that the use of expired Neomycin ear drops can result in antibiotic resistance. 

This makes bacteria stop responding to the med even when you start using the unexpired one. This is why you should not opt for expired antibiotics or any other medication for that matter (1). 

What to do if you have used expired Neomycin ear drops? 

If you have accidentally used expired Neomycin ear drops once or twice, it doesn’t matter. However, I would not recommend using them any further. 

It’s best to check the printed expiry date before using Neomycin ear drops if they have been sitting around your shelf for a while. Report to your healthcare provider if your symptoms worsen.

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U.S. Food and Drug Administration. Don’t Be Tempted to Use Expired Medicines [Internet]. Silver Spring (MD): U.S. Food and Drug Administration; 2021 [cited 2022 Oct 24]. Available from: